Enhanced bioavailability of eicosapentaenoic acid from fish oil after encapsulation within plant spore exines as microcapsules
Wakil, Ammar; Mackenzie, Grahame; Diego-Taboada, Alberto; Bell, J. Gordon; Atkin, Stephen L.
Alberto Diego-Taboada A.D.Taboada@hull.ac.uk
J. Gordon Bell
Stephen L. Atkin
Benefits of eicosapentaenoic acid (EPA) can be enhanced by raising their bioavailability through microencapsulation. Pollen can be emptied to form hollow shells, known as exines, and then used to encapsulate material, such as oils in a dry powder form. Six healthy volunteers ingested 4.6 g of fish oil containing 20% EPA in the form of ethyl ester first alone and then as 1:1 microencapsulated powder of exines and fish oil. Serum bioavailability of EPA was measured by area under curve (AUC(0-24)). The mean AUC(0-24) of EPA from ethyl ester with exine (M = 19.7, SD = 4.3) was significantly higher than ethyl ester without exines (M = 2, SD = 1.4, p < 0.01).The bioavailability of EPA is enhanced by encapsulation by pollen exines.
|Journal Article Type||Article|
|Publication Date||Jul 1, 2010|
|Peer Reviewed||Peer Reviewed|
|APA6 Citation||Wakil, A., Mackenzie, G., Diego-Taboada, A., Bell, J. G., & Atkin, S. L. (2010). Enhanced bioavailability of eicosapentaenoic acid from fish oil after encapsulation within plant spore exines as microcapsules. Lipids, 45(7), 645-649. doi:10.1007/s11745-010-3427-y|
|Keywords||Exines; Microencapsulation; Eicosapentaenoic acid; Bioavailability microspheres|