Skip to main content

Enhanced bioavailability of eicosapentaenoic acid from fish oil after encapsulation within plant spore exines as microcapsules

Wakil, Ammar; Mackenzie, Grahame; Diego-Taboada, Alberto; Bell, J. Gordon; Atkin, Stephen L.

Authors

Ammar Wakil

Grahame Mackenzie

Alberto Diego-Taboada A.D.Taboada@hull.ac.uk

J. Gordon Bell

Stephen L. Atkin



Abstract

Benefits of eicosapentaenoic acid (EPA) can be enhanced by raising their bioavailability through microencapsulation. Pollen can be emptied to form hollow shells, known as exines, and then used to encapsulate material, such as oils in a dry powder form. Six healthy volunteers ingested 4.6 g of fish oil containing 20% EPA in the form of ethyl ester first alone and then as 1:1 microencapsulated powder of exines and fish oil. Serum bioavailability of EPA was measured by area under curve (AUC(0-24)). The mean AUC(0-24) of EPA from ethyl ester with exine (M = 19.7, SD = 4.3) was significantly higher than ethyl ester without exines (M = 2, SD = 1.4, p < 0.01).The bioavailability of EPA is enhanced by encapsulation by pollen exines.

Journal Article Type Article
Publication Date Jul 1, 2010
Journal LIPIDS
Print ISSN 0024-4201
Electronic ISSN 1558-9307
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 45
Issue 7
Pages 645-649
APA6 Citation Wakil, A., Mackenzie, G., Diego-Taboada, A., Bell, J. G., & Atkin, S. L. (2010). Enhanced bioavailability of eicosapentaenoic acid from fish oil after encapsulation within plant spore exines as microcapsules. Lipids, 45(7), 645-649. doi:10.1007/s11745-010-3427-y
DOI https://doi.org/10.1007/s11745-010-3427-y
Keywords Exines; Microencapsulation; Eicosapentaenoic acid; Bioavailability microspheres
;