Ming Liu
Cucurbit[6]uril-based carbon dots for recognizing l-tryptophan and capecitabine
Liu, Ming; Cen, Ran; Lu, Ji Hong; Meng, Tie Hong; Li, Chun Rong; Redshaw, Carl; Prior, Timothy J.; Tao, Zhu; Xiao, Xin
Authors
Ran Cen
Ji Hong Lu
Tie Hong Meng
Chun Rong Li
Professor Carl Redshaw C.Redshaw@hull.ac.uk
Emeritus Professor
Dr Tim Prior T.Prior@hull.ac.uk
Senior Lecturer in Inorganic Chemistry
Zhu Tao
Xin Xiao
Abstract
Fluorescent nitrogen and fluorine doped carbon dots (CDs) were prepared by a hydrothermal method using levofloxacin (LVFX) and cucurbit[6]uril (Q[6]) as the nitrogen and carbon sources, respectively. Decomposition of LVFX occurred at elevated temperature affording N,N′-desethylene levofloxacin hydrochloride (N,N′-DLH). The crystal structure of the resulting inclusion complex N,N′-DLH@Q[6]·[CdCl4]2(H3O)·9H2O was determined, where N,N′-DLH is protonated on each of the terminal nitrogens and the quinone functionality is a quinol which forms an intramolecular hydrogen bond to the carboxylic acid. The synthesized N,N′-DLH containing Q[6]-CDs emitted intense blue fluorescence with high photostability and exhibited stability at high ionic strength. In particular, the original rigid macrocyclic skeletons of these hosts were retained during the fabrication process, which helps in uniquely distinguishing them from other reported CDs. Meanwhile, the performance of the Q[6]-CDs was characterized using fluorescence and NMR spectroscopies. Subsequently, using the obtained Q[6]-CDs, an efficient sensing method for l-tryptophan (l-Trp) and capecitabine (CAP) has been developed based on macrocyclic host-guest chemistry. Under applicable conditions, the detection limits for l-Trp and CAP were calculated to be 5.13 × 10−8 M and 1.48 × 10−8 M, respectively.
Citation
Liu, M., Cen, R., Lu, J. H., Meng, T. H., Li, C. R., Redshaw, C., Prior, T. J., Tao, Z., & Xiao, X. (in press). Cucurbit[6]uril-based carbon dots for recognizing l-tryptophan and capecitabine. Materials Chemistry Frontiers, https://doi.org/10.1039/d2qm00589a
Journal Article Type | Article |
---|---|
Acceptance Date | Aug 17, 2022 |
Online Publication Date | Sep 18, 2022 |
Deposit Date | Sep 6, 2022 |
Publicly Available Date | Sep 8, 2022 |
Journal | Materials Chemistry Frontiers |
Print ISSN | 2052-1537 |
Electronic ISSN | 2052-1537 |
Publisher | Royal Society of Chemistry |
Peer Reviewed | Peer Reviewed |
DOI | https://doi.org/10.1039/d2qm00589a |
Keywords | Materials Chemistry; General Materials Science |
Public URL | https://hull-repository.worktribe.com/output/4067637 |
Files
Published article
(2 Mb)
PDF
Publisher Licence URL
http://creativecommons.org/licenses/by/3.0
Copyright Statement
his article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
You might also like
Co/Mn-based 2D coordination polymers: synthesis, structure and ring opening polymerization
(2023)
Journal Article
A cucurbit[8]uril-based fluorescent probe for the selective detection of pymetrozine
(2023)
Journal Article
Supramolecular Self-assemblies of inverted cucurbit[6]uril with 1,5-pentanediamine
(2023)
Journal Article
Downloadable Citations
About Repository@Hull
Administrator e-mail: repository@hull.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2025
Advanced Search