Sajjad Chamani
Modulatory properties of curcumin in cancer: A narrative review on the role of interferons
Chamani, Sajjad; Moossavi, Maryam; Naghizadeh, Ali; Abbasifard, Mitra; Kesharwani, Prashant; Sathyapalan, Thozhukat; Sahebkar, Amirhossein
Authors
Maryam Moossavi
Ali Naghizadeh
Mitra Abbasifard
Prashant Kesharwani
Professor Thozhukat Sathyapalan T.Sathyapalan@hull.ac.uk
Professor of Diabetes, Endocrinology and Metabolism
Amirhossein Sahebkar
Abstract
The immune network is an effective network of cell types and chemical compounds established to maintain the body's homeostasis from foreign threats and to prevent the risk of a wide range of diseases; hence, its proper functioning and balance are essential. A dysfunctional immune system can contribute to various disorders, including cancer. Therefore, there has been considerable interest in molecules that can modulate the immune network. Curcumin, the active ingredient of turmeric, is one of these herbal remedies with many beneficial effects, including modulation of immunity. Curcumin is beneficial in managing various chronic inflammatory conditions, improving brain function, lowering cardiovascular disease risk, prevention and management of dementia, and prevention of aging. Several clinical studies have supported this evidence, suggesting curcumin to have an immunomodulatory and anti-inflammatory function; nevertheless, its mechanism of action is still not clear. In the current review, we aim to explore the modulatory function of curcumin through interferons in cancers.
Citation
Chamani, S., Moossavi, M., Naghizadeh, A., Abbasifard, M., Kesharwani, P., Sathyapalan, T., & Sahebkar, A. (in press). Modulatory properties of curcumin in cancer: A narrative review on the role of interferons. Phytotherapy Research, https://doi.org/10.1002/ptr.7734
| Journal Article Type | Review |
|---|---|
| Acceptance Date | Jan 10, 2023 |
| Online Publication Date | Feb 6, 2023 |
| Deposit Date | Feb 18, 2023 |
| Publicly Available Date | Feb 7, 2024 |
| Journal | Phytotherapy Research |
| Print ISSN | 0951-418X |
| Electronic ISSN | 1099-1573 |
| Publisher | Wiley |
| Peer Reviewed | Peer Reviewed |
| DOI | https://doi.org/10.1002/ptr.7734 |
| Keywords | Cancer; Curcumin; Immunomodulation; Turmeric |
| Public URL | https://hull-repository.worktribe.com/output/4202284 |
Files
This file is under embargo until Feb 7, 2024 due to copyright reasons.
Contact T.Sathyapalan@hull.ac.uk to request a copy for personal use.
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