Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis

Ravindhran, B; Lathan, R; Staniland, T; Sidapra, M; Carradice, D; Chetter, I; Smith, G; Saxton, J; Pymer, S

Abstract

Background and objectives: The aim of this systematic review is to explore the current evidence surrounding the changes in functional status following open or endovascular abdominal aortic aneurysm (AAA) repair and the role of postoperative exercise-based rehabilitation programmes.
Methods: The proposed study will incorporate two separate systematic reviews within it, one to assess changes in functional status (component 1) and another to consider the role of exercise-based rehabilitation for improving functional status (component 2), both following AAA repair. The Medline, EMBASE and Cochrane CENTRAL databases will be searched using two separate search strategies including the terms “aortic aneurysm”, “functional capacity”, “functional decline” and” exercise therapy”. We plan to include all prospective randomised and non-randomised trials that have considered the impact of AAA repair on functional status and/or the effect of exercise-based rehabilitation following AAA repair. For component 1, the primary outcome will be changes in objective measures of functional capacity or physical function following AAA repair and, for component 2, it will be changes in physical function or functional capacity following exercise-based rehabilitation after AAA repair. The extracted data will include study characteristics – ie, sample size, a description of the intervention and control conditions (where applicable), outcome measures, length of follow-up and main findings related to outcome measures. For both components a narrative synthesis will be produced, supported by a summary table. We intend to conduct quantitative meta-analyses for both components. For each selected outcome we plan to evaluate the certainty of evidence based on the GRADE approach and risk of bias of included studies will be assessed using the Cochrane tool.
Conclusions: Based on a lack of current evidence, we present a protocol for a systematic review to investigate the functional changes associated with open and endovascular AAA repair and the potential value of postoperative exercise rehabilitation.

Citation

Ravindhran, B., Lathan, R., Staniland, T., Sidapra, M., Carradice, D., Chetter, I., Smith, G., Saxton, J., & Pymer, S. (2022). Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis. Journal of Vascular Societies Great Britain and Ireland, 2(1), 41-45. https://doi.org/10.54522/jvsgbi.2022.042

• Journal Article Type: Article
• Acceptance Date: Jul 29, 2022
• Online Publication Date: Nov 21, 2022
• Publication Date: Nov 1, 2022
• Deposit Date: Apr 24, 2023
• Journal: Journal of Vascular Societies Great Britain & Ireland
• Publisher: Vascular Society for Great Britain and Ireland
• Peer Reviewed: Peer Reviewed
• Volume: 2
• Issue: 1
• Pages: 41-45
• DOI: https://doi.org/10.54522/jvsgbi.2022.042
• Keywords: Abdominal aortic aneurysm; Exercise therapy; Function recovery; Postoperative care; Rehabilitation
• Public URL: https://hull-repository.worktribe.com/output/4269681