Statins and ischaemia reperfusion injury: a molecular biological review

N.A. Abdul Rahman, M.; C. Chetter, Ian

Abstract

The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the effect of ischaemia reperfusion injury. This review considers the biomolecular processes that may lead to this beneficial effect.

Citation

N.A. Abdul Rahman, M., & C. Chetter, I. (2010). Statins and ischaemia reperfusion injury: a molecular biological review. Current Vascular Pharmacology, 8(6), 831-835. https://doi.org/10.2174/157016110793563780

• Journal Article Type: Article
• Acceptance Date: Dec 31, 2010
• Publication Date: Nov 1, 2010
• Journal: Current Vascular Pharmacology
• Print ISSN: 1570-1611
• Publisher: Bentham Science Publishers
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 6
• Pages: 831-835
• DOI: https://doi.org/10.2174/157016110793563780
• Keywords: Pharmacology; Cardiology and Cardiovascular Medicine
• Public URL: https://hull-repository.worktribe.com/output/432608