Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol

Prosser, J; Staniland, T; Harwood, AE; Ravindhran, B; McGregor, G; Huang, C; Twiddy, M; Nicholls, AR; Ingle, L; Long, J; Chetter, IC; Pymer, S

Abstract

Introduction: The aim of this systematic review is to consider the evidence base for home-based high intensity interval training (HIIT) in patients with intermittent claudication (IC). Prior knowledge of the evidence base suggests that there may be little research considering HIIT in patients with IC. If so, the evidence base across all cardiovascular diseases will be considered.

Methods: Medline, EMBASE, CINAHL and Cochrane CENTRAL databases will be searched for terms including ‘peripheral arterial disease’, ‘intermittent claudication’, ‘home-based exercise’, ‘high intensity interval training’ and ‘home-based high intensity interval training’. All prospective randomised trials and non-randomised studies considering home-based HIIT in patients with IC will be included. Studies will not be excluded based on the use of a comparator arm, meaning single-arm studies as well as multi-arm trials will also be included. If appropriate, based on the extant literature, a meta-analysis of randomised controlled trials will be conducted. The outcomes of interest will include intervention components, intervention feasibility (based on uptake and completion rates), intervention tolerability (based on compliance and adherence to the intervention), maximum walking distance, pain-free walking distance, quality of life and cardiorespiratory fitness.

Conclusion: This review aims to assess the evidence for home-based HIIT in patients with IC, to establish its feasibility and to inform the refinement of an existing supervised HIIT intervention to allow it to also be delivered remotely. Following this, a pilot randomised controlled trial to compare HIIT versus usual care supervised exercise programmes will be developed. For this, the interventions will be delivered either in person or remotely in real-time, depending on centre availability and patient preference.

Citation

Prosser, J., Staniland, T., Harwood, A., Ravindhran, B., McGregor, G., Huang, C., Twiddy, M., Nicholls, A., Ingle, L., Long, J., Chetter, I., & Pymer, S. (2024). Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol. Journal of Vascular Societies Great Britain and Ireland, 3(3), 155-159. https://doi.org/10.54522/jvsgbi.2024.103

• Journal Article Type: Article
• Acceptance Date: Apr 2, 2024
• Online Publication Date: May 24, 2024
• Publication Date: May 1, 2024
• Deposit Date: Jun 3, 2024
• Journal: Journal of Vascular Societies Great Britain & Ireland
• Publisher: Vascular Society for Great Britain and Ireland
• Peer Reviewed: Peer Reviewed
• Volume: 3
• Issue: 3
• Pages: 155-159
• DOI: https://doi.org/10.54522/jvsgbi.2024.103
• Keywords: High intensity interval training; Home-based exercise; Intermittent claudication; Peripheral arterial disease; Supervised exercise therapy
• Public URL: https://hull-repository.worktribe.com/output/4701204