Skip to main content

Research Repository

Advanced Search

Templated mineralization by charge-modified cowpea mosaic virus

Aljabali, Alaa A A; Evans, David J.


Alaa A A Aljabali

David J. Evans


Templated mineralization of virus particles provides routes to narrowly dispersed nanoparticles that are not readily prepared by other means. The templated mineralization of metal or metal oxide on the external surface of wild-type cowpea mosaic virus (CPMV), a plant virus, is facilitated by increasing the external surface negative charge. This is achieved by the chemical modification of surface lysine groups by succinic anhydride. Hence, for example, treatment of charge-modified CPMV succinamate with a 1:2 mixture of iron(II) and iron(III) salts, followed by raising the pH to 10.2, led to the formation of narrowly dispersed, CPMV-templated, magnetite (Fe3O4) nanoparticles.


Aljabali, A. A. A., & Evans, D. J. (2014). Templated mineralization by charge-modified cowpea mosaic virus. In Methods in Molecular Biology; Virus Hybrids as Nanomaterials, 89-95. Humana Press. doi:10.1007/978-1-62703-751-8_6

Online Publication Date Oct 30, 2013
Publication Date Jan 1, 2014
Deposit Date May 23, 2016
Publicly Available Date May 23, 2016
Journal Virus hybrids as nanomaterials
Print ISSN 1064-3745
Electronic ISSN 1940-6029
Publisher Humana Press
Peer Reviewed Not Peer Reviewed
Volume 1108
Pages 89-95
Book Title Methods in Molecular Biology; Virus Hybrids as Nanomaterials
ISBN 9781627037501; 9781627037518
Keywords Nanoparticles, Iron oxide, Magnetite, Cowpea mosaic virus, Templated mineralization
Public URL
Publisher URL The final publication is available at Springer via
Copyright Statement © 2016 the authors


You might also like

Downloadable Citations