Templated mineralization by charge-modified cowpea mosaic virus

Aljabali, Alaa A A; Evans, David J.

Abstract

Templated mineralization of virus particles provides routes to narrowly dispersed nanoparticles that are not readily prepared by other means. The templated mineralization of metal or metal oxide on the external surface of wild-type cowpea mosaic virus (CPMV), a plant virus, is facilitated by increasing the external surface negative charge. This is achieved by the chemical modification of surface lysine groups by succinic anhydride. Hence, for example, treatment of charge-modified CPMV succinamate with a 1:2 mixture of iron(II) and iron(III) salts, followed by raising the pH to 10.2, led to the formation of narrowly dispersed, CPMV-templated, magnetite (Fe3O4) nanoparticles.

Citation

Aljabali, A. A. A., & Evans, D. J. (2014). Templated mineralization by charge-modified cowpea mosaic virus. In Methods in Molecular Biology; Virus Hybrids as Nanomaterials (89-95). Totowa, NJ: Humana Press. https://doi.org/10.1007/978-1-62703-751-8_6

• Online Publication Date: Oct 30, 2013
• Publication Date: Jan 1, 2014
• Deposit Date: May 23, 2016
• Publicly Available Date: Oct 27, 2022
• Journal: Virus hybrids as nanomaterials
• Print ISSN: 1064-3745
• Electronic ISSN: 1940-6029
• Publisher: Humana Press
• Peer Reviewed: Not Peer Reviewed
• Volume: 1108
• Pages: 89-95
• Book Title: Methods in Molecular Biology; Virus Hybrids as Nanomaterials
• ISBN: 9781627037501; 9781627037518
• DOI: https://doi.org/10.1007/978-1-62703-751-8_6
• Keywords: Nanoparticles, Iron oxide, Magnetite, Cowpea mosaic virus, Templated mineralization
• Public URL: https://hull-repository.worktribe.com/output/438538
• Publisher URL: The final publication is available at Springer via http://dx.doi.org/10.1007/978-1-62703-751-8_6