The long-term impact of glucose monitoring with the FreeStyle Libre on glycaemic control and hypoglycaemia awareness in people with type1 diabetes: Insights from the Association of British Clinical Diabetologists national audit

Shah, Najeeb; Deshmukh, Harshal; Wilmot, Emma G; Patmore, Jane; Christian, Peter; Barnes, Dennis J; Walton, Christopher; Ryder, Robert E J; Sathyapalan, Thozhukat

Abstract

Aims: To investigate the change in glycated haemoglobin (HbA1c), hypoglycaemia awareness and diabetes-related distress in people with type 1 diabetes (T1D) using FreeStyle Libre (FSL) over a 2-year follow-up period. Methods: FSL user data from U.K wide hospitals collected during routine clinical care were analysed. People living with T1D were categorised into four groups based on the duration of follow-up. Group I (< 1 year, n = 6940), group II (1 to 1.5 years, n = 662), group III (1.5 to 2 years, n = 385), and group IV (> 2 years, n = 642). The t-test was used to compare the baseline and follow-up HbA1c, GOLD score (a measure of hypoglycaemia awareness) and diabetes-related distress scale (DDS score) (quality of life measure). Results: The study consisted of 16,834 people, with follow-up data available for 8,629 participants. The change in HbA1c, GOLD and DDS score from baseline within the follow-up sub-groups (group I vs group II vs group III vs group IV) was HbA1c (−6 vs −6 vs −4 vs −4 mmol/mol; p < 0.001) (−0.55 vs −0.55 vs −0.37 vs −0.37 %), GOLD score (−0.31 vs −0.45 vs −0.26 vs −0.42; p < 0.0001 group I, II, IV and p 0.07 group III), and DDS score(−0.59 vs −0.58 vs −0.63 vs −0.50; p < 0.001), respectively. Conclusions: In people with T1D, FSL use resulted in a sustained improvement in HbA1c, hypoglycaemia awareness and diabetes-related distress for over two years.

Citation

Shah, N., Deshmukh, H., Wilmot, E. G., Patmore, J., Christian, P., Barnes, D. J., Walton, C., Ryder, R. E. J., & Sathyapalan, T. (2023). The long-term impact of glucose monitoring with the FreeStyle Libre on glycaemic control and hypoglycaemia awareness in people with type1 diabetes: Insights from the Association of British Clinical Diabetologists national audit. Diabetic medicine, 40(6), Article e15070. https://doi.org/10.1111/dme.15070

• Journal Article Type: Article
• Acceptance Date: Feb 11, 2023
• Online Publication Date: Feb 16, 2023
• Publication Date: Jun 1, 2023
• Deposit Date: Oct 25, 2023
• Publicly Available Date: Mar 20, 2024
• Journal: Diabetic Medicine
• Electronic ISSN: 1464-5491
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 40
• Issue: 6
• Article Number: e15070
• DOI: https://doi.org/10.1111/dme.15070
• Keywords: Diabetes-related distress; FreeStyle libre monitoring; Glycaemic control; Hypoglycaemia awareness; Type 1 diabetes
• Public URL: https://hull-repository.worktribe.com/output/4423956