Colloid particle formulations for antimicrobial applications

Halbus, Ahmed F.; Horozov, Tommy S.; Paunov, Vesselin N.

Abstract

Colloidal particles are being extensively studied in various antimicrobial applications due to their small size to volume ratio and ability to exhibit a wide spectrum of antibacterial, antifungal, antialgal and antiviral action. The present review focuses on various nanoparticles (NPs) of inorganic, organic and hybrid materials, and discusses some of the methods for their preparation as well as mechanisms of their antimicrobial action. We consider the antimicrobial applications of metal oxide nanoparticles (ZnO, MgO, CuO, Cu2O, Al2O3, TiO2, CeO2 and Y2O3), metal nanoparticles (NPs), such as copper, silver and gold, metal hydroxide NPs such as Mg(OH)2 as well as hybrid NPs made from biodegradable materials, such as chitosan, lignin and dextran, loaded with other antimicrobial agents. Recent developments for targeted delivery of antimicrobials by using colloid antibodies for microbial cell shape and surface recognition are also discussed. We also consider recent advances in the functionalization of nanoparticles and their potential antimicrobial applications as a viable alternative of conventional antibiotics and antiseptic agents which can help to tackle antimicrobial resistance. The review also covers the recently developed environmentally benign NPs (EbNPs) as a “safer-by-design” green chemistry solution of the post use fate of antimicrobial nanomaterials.

Citation

Halbus, A. F., Horozov, T. S., & Paunov, V. N. (2017). Colloid particle formulations for antimicrobial applications. Advances in Colloid and Interface Science, 249, 134-148. https://doi.org/10.1016/j.cis.2017.05.012

• Journal Article Type: Article
• Acceptance Date: May 10, 2017
• Online Publication Date: May 12, 2017
• Publication Date: 2017-11
• Deposit Date: May 18, 2017
• Publicly Available Date: Nov 29, 2018
• Journal: Advances in colloid and interface science
• Print ISSN: 0001-8686
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 249
• Pages: 134-148
• DOI: https://doi.org/10.1016/j.cis.2017.05.012
• Keywords: Antimicrobials; Nanoparticles; Antimicrobial resistance; Metal oxide nanoparticles; Environmentally benign nanoparticles; Colloid antibodies
• Public URL: https://hull-repository.worktribe.com/output/450693
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0001868617300064
• Contract Date: May 18, 2017