Liquid viruses by nanoscale engineering of capsid surfaces

Patil, Avinash J.; McGrath, Nina; Elaine Barclay, J.; Evans, David J.; Cölfen, Helmut; Manners, Ian; Perriman, Adam W.; Mann, Stephen

Abstract

Surface engineering of plant virus capsids via cationization and stoichiometric coupling of a polymer surfactant coronal layer produces a highly concentrated, solvent-free liquid virus at 28 °C. These ionic bionanoconstructs are viscoelastic, retain plant infectivity and can be dispersed in a range of organic solvents for aerosol delivery.

Citation

Patil, A. J., McGrath, N., Elaine Barclay, J., Evans, D. J., Cölfen, H., Manners, I., Perriman, A. W., & Mann, S. (2012). Liquid viruses by nanoscale engineering of capsid surfaces. Advanced materials, 24(33), 4557-4563. https://doi.org/10.1002/adma.201201032

• Journal Article Type: Article
• Acceptance Date: Jun 1, 2012
• Online Publication Date: Jul 16, 2012
• Publication Date: Aug 28, 2012
• Deposit Date: Nov 13, 2014
• Journal: Advanced Materials
• Print ISSN: 0935-9648
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 24
• Issue: 33
• Pages: 4557-4563
• DOI: https://doi.org/10.1002/adma.201201032
• Keywords: Mechanical Engineering; General Materials Science; Mechanics of Materials
• Public URL: https://hull-repository.worktribe.com/output/466861
• Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201201032
• Contract Date: Nov 23, 2017