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Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial

Reid, Marie; Hammersley, Richard; Duffy, Maresa; Ballantyne, Carrie


Professor Marie Reid
Professor/ Director of MSc Clinical Applications of Psychology/ Athena Swan lead for Psychology

Richard Hammersley

Maresa Duffy

Carrie Ballantyne


To investigate whether obese women can compensate for sucrose added to the diet when it is given blind, rather than gaining weight or exhibiting dysfunctional regulation of intake, in the present study, forty-one healthy obese (BMI 30–35 kg/m2) women (age 20–50 years), not currently dieting, were randomly assigned to consume sucrose (n 20) or aspartame (n 21) drinks over 4 weeks in a parallel single-blind design. Over the 4 weeks, one group consumed 4 × 250 ml sucrose drinks (total 1800 kJ/d) and the other group consumed 4 × 250 ml aspartame drinks. During the baseline week and experimental weeks, body weight and other biometric data were measured and steps per day, food intake using 7 d unweighed food diaries, and mood using ten- or seven-point Likert scales four times a day were recorded. At the end of the experiment, the participants weighed 1·72 (se 0·47) kg less than the value predicted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) model; the predicted body weight accounted for 94·3 % of the variance in the observed body weight and experimental group accounted for a further 1·1 % of the variance in the observed body weight, showing that women consuming sucrose drinks gained significantly less weight than predicted. The reported daily energy intake did not increase significantly, and sucrose supplements significantly reduced the reported voluntary sugar, starch and fat intake compared with aspartame. There were no effects on appetite or mood. Over 4 weeks, as part of everyday eating, sucrose given blind in soft drinks was partially compensated for by obese women, as in previous experiments with healthy and overweight participants.


Reid, M., Hammersley, R., Duffy, M., & Ballantyne, C. (2014). Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial. British Journal of Nutrition, 111(3), 563-570 .

Journal Article Type Article
Acceptance Date Jul 15, 2013
Online Publication Date Oct 25, 2013
Publication Date Feb 14, 2014
Deposit Date Nov 13, 2014
Publicly Available Date Nov 13, 2014
Journal British journal of nutrition
Print ISSN 1475-2662
Electronic ISSN 1475-2662
Publisher Cambridge University Press (CUP)
Peer Reviewed Peer Reviewed
Volume 111
Issue 3
Pages 563-570
Keywords Nutrition and Dietetics; Medicine (miscellaneous)
Public URL
Publisher URL
Additional Information This is a copy on an article first published in: British journal of nutrition, 2013, v.111, issue 3


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The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike licence <>

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