Building ADMISSION – A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital

Witham, Miles D; Bartle, Victoria; Bellass, Sue; Bunn, Jonathan G; Cartner, Duncan; Cordell, Heather J; Doal, Rominique; Evison, Felicity; Gallier, Suzy; Harris, Steve; Hillman, Susan J; Holding, Ray; Leroux, Peta; Marshall, Tom; Matthews, Fiona E; Missier, Paolo; Nair, Anand; Osman, Mo; Pearson, Ewan R; Plummer, Chris; Pretorius, Sara; Richardson, Sarah J; Robinson, Sian M; Sapey, Elizabeth; Scharf, Thomas; Shah, Rupal; Shahmandi, Marzieh; Singer, Mervyn; Suklan, Jana; Wason, James MS; Cooper, Rachel; Sayer, Avan A

Abstract

Background
Multiple long-term conditions (MLTCs; commonly referred to as multimorbidity) are highly prevalent among people admitted to hospital and are therefore of critical importance to hospital-based healthcare systems. To date, most research on MLTCs has been conducted in primary care or the general population with comparatively little work undertaken in the hospital setting.
Purpose
To describe the rationale and content of ADMISSION: a four-year UK Research and Innovation and National Institute of Health and Care Research funded interdisciplinary programme that seeks, in partnership with public contributors, to transform care for people living with MLTCs admitted to hospital.
Research design
Based across five UK academic centres, ADMISSION combines expertise in clinical medicine, epidemiology, informatics, computing, biostatistics, social science, genetics and care pathway mapping to examine patterns of conditions, mechanisms, consequences and pathways of care for people with MLTCs admitted to hospital.
Data collection
The programme uses routinely collected electronic health record data from large UK teaching hospitals, population-based cohort data from UK Biobank and routinely collected blood samples from The Scottish Health Research Register and Biobank (SHARE). These approaches are complemented by focused qualitative work exploring the perspectives of healthcare professionals and the lived experience of people with MLTCs admitted to hospital.
Conclusion
ADMISSION will provide the necessary foundations to develop novel ways to prevent and treat MLTCs and their consequences in people admitted to hospital and to improve care systems and the quality of care for this underserved group.

Citation

Witham, M. D., Bartle, V., Bellass, S., Bunn, J. G., Cartner, D., Cordell, H. J., Doal, R., Evison, F., Gallier, S., Harris, S., Hillman, S. J., Holding, R., Leroux, P., Marshall, T., Matthews, F. E., Missier, P., Nair, A., Osman, M., Pearson, E. R., Plummer, C., …Sayer, A. A. (2025). Building ADMISSION – A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital. Journal of Multimorbidity and Comorbidity, 15, https://doi.org/10.1177/26335565251317940

• Journal Article Type: Article
• Acceptance Date: Jan 20, 2025
• Online Publication Date: Feb 1, 2025
• Publication Date: 2025
• Deposit Date: Apr 16, 2025
• Publicly Available Date: Apr 17, 2025
• Journal: Journal of Multimorbidity and Comorbidity
• Print ISSN: 2633-5565
• Electronic ISSN: 2633-5565
• Publisher: SAGE Publications
• Peer Reviewed: Peer Reviewed
• Volume: 15
• DOI: https://doi.org/10.1177/26335565251317940
• Public URL: https://hull-repository.worktribe.com/output/5130860