Comparison of DOPA and DPPA liposome templates for the synthesis of calcium phosphate nanoshells

Yeo, Chiew Hwee; Zein, Sharif Hussein Sharif; Ahmad, Abdul Latif; McPhail, David S.

Abstract

The aim of this paper is to synthesise calcium phosphate (CaP) nanoshells by controlling their particle size and shape using negatively charged liposomes (1,2 dioleoyl-sn-glycero-3 phosphate sodium salt (DOPA) and 1,2-dipalmitoyl-sn- glycero-3-phosphate sodium salt (DPPA)) as a template. The morphology, particle size, size distribution and zeta potential properties of DOPA and DPPA liposome templates were determined. The results showed that both DOPA and DPPA formed spherical nanoshell structures to be used as templates for the synthesis of CaP nanoshells. By using the DOPA template, spherical CaPs structures with a mean particle size of 197.5 ± 5.8 nm were successfully formed. In contrast, needle or irregularly shaped CaP particles were observed when using the DPPA template.

Citation

Yeo, C. H., Zein, S. H. S., Ahmad, A. L., & McPhail, D. S. (2012). Comparison of DOPA and DPPA liposome templates for the synthesis of calcium phosphate nanoshells. Ceramics international, 38(1), 561-570. https://doi.org/10.1016/j.ceramint.2011.07.044

• Journal Article Type: Article
• Acceptance Date: Jul 22, 2011
• Online Publication Date: Jul 29, 2011
• Publication Date: 2012-01
• Deposit Date: Jul 7, 2020
• Journal: Ceramics International
• Print ISSN: 0272-8842
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Issue: 1
• Pages: 561-570
• DOI: https://doi.org/10.1016/j.ceramint.2011.07.044
• Keywords: Calcium phosphates; Nanoshells; Liposomes; Template
• Public URL: https://hull-repository.worktribe.com/output/549906
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S0272884211006833?via%3Dihub