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Effect of spirometry on intra-thoracic pressures

Tiller, Nicholas B.; Simpson, Andrew J.


Nicholas B. Tiller



Due to the high intra-thoracic pressures associated with forced vital capacity manoeuvres, spirometry is contraindicated for vulnerable patients. However, the typical pressure response to spirometry has not been reported. Eight healthy, recreationally-active men performed spirometry while oesophageal pressure was recorded using a latex balloon-tipped catheter.


Peak oesophageal pressure during inspiration was − 47 ± 9 cmH2O (37 ± 10% of maximal inspiratory pressure), while peak oesophageal pressure during forced expiration was 102 ± 34 cmH2O (75 ± 17% of maximal expiratory pressure). The deleterious consequences of spirometry might be associated with intra-thoracic pressures that approach maximal values during forced expiration.


Tiller, N. B., & Simpson, A. J. (2018). Effect of spirometry on intra-thoracic pressures. BMC research notes, 11(1), Article 110.

Journal Article Type Article
Acceptance Date Feb 1, 2018
Online Publication Date Feb 8, 2018
Publication Date Feb 8, 2018
Deposit Date Feb 9, 2018
Publicly Available Date Feb 13, 2018
Journal BMC Research Notes
Print ISSN 1756-0500
Electronic ISSN 1756-0500
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 11
Issue 1
Article Number 110
Keywords General Biochemistry, Genetics and Molecular Biology; General Medicine
Public URL
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