Skip to main content

Effect of spirometry on intra-thoracic pressures

Tiller, Nicholas B.; Simpson, Andrew J.


Nicholas B. Tiller



Due to the high intra-thoracic pressures associated with forced vital capacity manoeuvres, spirometry is contraindicated for vulnerable patients. However, the typical pressure response to spirometry has not been reported. Eight healthy, recreationally-active men performed spirometry while oesophageal pressure was recorded using a latex balloon-tipped catheter.


Peak oesophageal pressure during inspiration was − 47 ± 9 cmH2O (37 ± 10% of maximal inspiratory pressure), while peak oesophageal pressure during forced expiration was 102 ± 34 cmH2O (75 ± 17% of maximal expiratory pressure). The deleterious consequences of spirometry might be associated with intra-thoracic pressures that approach maximal values during forced expiration.

Journal Article Type Article
Publication Date Feb 8, 2018
Journal BMC Research Notes
Print ISSN 1756-0500
Electronic ISSN 1756-0500
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 11
Issue 1
Article Number 110
APA6 Citation Tiller, N. B., & Simpson, A. J. (2018). Effect of spirometry on intra-thoracic pressures. BMC research notes, 11(1), doi:10.1186/s13104-018-3217-9. ISSN 1756-0500
Keywords General Biochemistry, Genetics and Molecular Biology; General Medicine
Publisher URL
Copyright Statement © The Author(s) 2018


You might also like

Downloadable Citations