Endothelin receptor antagonists and scleroderma related digital ulcers
(2013)
Journal Article
Lee, W. Y., Faruqi, S., & Morice, A. H. (2013). Endothelin receptor antagonists and scleroderma related digital ulcers. Acta Reumatologica Portuguesa, 38(1), 58-59
All Outputs (204)
Management of patients with chronic cough using a clinical protocol: A prospective observational study (2013)
Journal Article
Ojoo, O. C., Everett, C. F., Mulrennan, S. A., Faruqi, S., Kastelik, J. A., & Morice, A. H. (2013). Management of patients with chronic cough using a clinical protocol: A prospective observational study. Cough, 9(1), Article 2. https://doi.org/10.1186/1745-9974-9-2Background and aims: Chronic cough is a common symptom the aetiology of which can be challenging to diagnose. Diagnostic protocols for chronic cough have required the use of specialist investigations which are not always easily available. We wanted t... Read More about Management of patients with chronic cough using a clinical protocol: A prospective observational study.
Novel antitussive strategies (2012)
Journal Article
Morjaria, J. B., Dickinson, R. S., & Morice, A. H. (2013). Novel antitussive strategies. Drug Discovery Today, 18(7-8), 380-388. https://doi.org/10.1016/j.drudis.2012.11.004Acute and chronic cough represent one of the most common symptoms of medical importance but effective pharmacotherapy is, to all intents and purposes, absent. Numerous initiatives targeting the recently discovered tussive pathways are in progress. He... Read More about Novel antitussive strategies.
Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis (2012)
Journal Article
Fahim, A., Crooks, M., Wilmot, R., Campbell, A. P., Morice, A., & Hart, S. (2012). Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis. Respirology : official journal of the Asian Pacific Society of Respirology, 17(8), 1247-1252. https://doi.org/10.1111/j.1440-1843.2012.02231.xBackground and objective: Idiopathic pulmonary fibrosis (IPF) is the commonest idiopathic interstitial pneumonia and carries a poor prognosis. Epidemiological evidence suggests that patients with IPF have an increased risk of developing lung cancer.... Read More about Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis.
Chronic cough and obstructive sleep apnoea: Reflux-associated cough hypersensitivity? (2012)
Journal Article
Faruqi, S., Fahim, A., & Morice, A. H. (2012). Chronic cough and obstructive sleep apnoea: Reflux-associated cough hypersensitivity?. European respiratory journal, 40(4), 1049-1050. https://doi.org/10.1183/09031936.00025012
Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology (2012)
Journal Article
Pathmanathan, S., Morjaria, J. B., Morice, A. H., & Jackson, W. (2012). Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology. Cough, 8(1), Article 6. https://doi.org/10.1186/1745-9974-8-6Chronic cough is a common symptom carrying significant morbidity which can occur as a result of oesophageal dysmotility. Here we report 2 patients with musculoskeletal disease presenting with chronic cough to our tertiary cough clinic. Prior to refer... Read More about Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology.
A case of cough and breathlessness (2012)
Journal Article
Esterbrook, G., Molyneux, I., Clark, A. L., & Morice, A. H. (2013). A case of cough and breathlessness. Thorax, 68(3), 302-304. https://doi.org/10.1136/thoraxjnl-2012-202494
Neurological conditions presenting as airway reflux cough (2012)
Journal Article
Karur, P. S., Morjaria, J. B., Wright, C., & Morice, A. H. (2012). Neurological conditions presenting as airway reflux cough. European Respiratory Review, 21(125), 257-259. https://doi.org/10.1183/09059180.00000212
Fundoplication in chronic intractable cough (2012)
Journal Article
Faruqi, S., Sedman, P., Jackson, W., Molyneux, I., & Morice, A. H. (2012). Fundoplication in chronic intractable cough. Cough, 8(1), Article 3. https://doi.org/10.1186/1745-9974-8-3Background: Airway reflux is a common cause of chronic cough and this is often refractory to medical therapy. Surgery in the form of Nissen fundoplication has been highly successful in the treatment of the classic reflux symptoms of heartburn and dys... Read More about Fundoplication in chronic intractable cough.
Comparison of the effect of high-dose inhaled budesonide and fluticasone on adrenal function in patients with severe chronic obstructive pulmonary disease (2012)
Journal Article
Fahim, A., Faruqi, S., Wright, C. E., Kastelik, J. A., & Morice, A. H. (2012). Comparison of the effect of high-dose inhaled budesonide and fluticasone on adrenal function in patients with severe chronic obstructive pulmonary disease. Annals of Thoracic Medicine, 7(3), 140-144. https://doi.org/10.4103/1817-1737.98846Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of respiratory-related morbidity and mortality. Inhaled steroids are frequently used in patients with moderate to severe disease and may lead to adrenal suppression. Object... Read More about Comparison of the effect of high-dose inhaled budesonide and fluticasone on adrenal function in patients with severe chronic obstructive pulmonary disease.
After repair of tracheo-oesophageal atresia (2012)
Journal Article
Love, C., & Morice, A. H. (2012). After repair of tracheo-oesophageal atresia. BMJ, 344(7865), Article e3517. https://doi.org/10.1136/bmj.e3517
Telemonitoring, COPD and cough counting (2012)
Journal Article
Junais, A., Innes, A., Morice, A. H., Barrett, D. I., & Stephenson, G. (2012). Telemonitoring, COPD and cough counting. Journal of telemedicine and telecare, 18(5), 301-302. https://doi.org/10.1258/jtt.2012.120102
Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial (2012)
Journal Article
Parry, G. D., Cooper, C. L., Moore, J. M., Yadegarfar, G., Campbell, M. J., Esmonde, L., Morice, A. H., & Hutchcroft, B. J. (2012). Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial. Respiratory medicine, 106(6), 802-810. https://doi.org/10.1016/j.rmed.2012.02.006Background: High levels of asthma-related fear and panic exacerbate asthma symptoms and complicate the management of asthma. Asthma-specific fear may be reduced by a cognitive behavioural intervention. We aimed to test if there is a reduction in asth... Read More about Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial.
Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts (2012)
Journal Article
Sadofsky, L. R., Ramachandran, R., Crow, C., Cowen, M., Compton, S. J., & Morice, A. H. (2012). Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts. Experimental Lung Research, 38(2), 75-81. https://doi.org/10.3109/01902148.2011.644027Lung fibroblasts are involved in interstitial lung disease, chronic asthma, and chronic obstructive pulmonary disease (COPD). The expanded fibroblast population in airway disease leads to airway remodeling and contributes to the inflammatory process... Read More about Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts.
Cough hypersensitivity syndrome is an important clinical concept: A pro/con debate (2011)
Journal Article
Morice, A. H., McGarvey, L. P., & Dicpinigaitis, P. V. (2012). Cough hypersensitivity syndrome is an important clinical concept: A pro/con debate. Lung, 190(1), 3-9. https://doi.org/10.1007/s00408-011-9351-yThe major etiologies of chronic cough are generally accepted to consist of upper airway cough syndrome (formerly postnasal drip syndrome), eosinophilic airway inflammation (asthma, nonasthmatic eosinophilic bronchitis), and gastroesophageal reflux di... Read More about Cough hypersensitivity syndrome is an important clinical concept: A pro/con debate.
Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study (2011)
Journal Article
Faruqi, S., Molyneux, I. D., Fathi, H., Wright, C., Thompson, R., & Morice, A. H. (2011). Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study. Respirology : official journal of the Asian Pacific Society of Respirology, 16(7), 1150-1156. https://doi.org/10.1111/j.1440-1843.2011.02014.xBackground and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication. Esomeprazole is a proton pump inhibitor licensed for the lon... Read More about Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study.
Bronchoconstriction and airway remodeling [2] (2011)
Journal Article
Morjaria, J., Hart, S., & Morice, A. H. (2011). Bronchoconstriction and airway remodeling [2]. New England Journal of Medicine, 365(12), 1156-1157. https://doi.org/10.1056/NEJMc1107353
Palmitoylation of human proteinase-activated receptor-2 differentially regulates receptor-triggered ERK1/2 activation, calcium signalling and endocytosis (2011)
Journal Article
Botham, A., Guo, X., Xiao, Y. P., Morice, A. H., Compton, S., & Sadofsky, L. R. (2011). Palmitoylation of human proteinase-activated receptor-2 differentially regulates receptor-triggered ERK1/2 activation, calcium signalling and endocytosis. Biochemical Journal, 438(2), 359-367. https://doi.org/10.1042/BJ20101958hPAR2 (human proteinase-activated receptor-2) is a member of the novel family of proteolytically activated GPCRs (G-protein-coupled receptors) termed PARs (proteinase-activated receptors). Previous pharmacological studies have found that activation o... Read More about Palmitoylation of human proteinase-activated receptor-2 differentially regulates receptor-triggered ERK1/2 activation, calcium signalling and endocytosis.
Gastro-oesophageal reflux, eosinophilic airway inflammation and chronic cough (2011)
Journal Article
Pacheco, A., Faro, V., Cobeta, I., Royuela, A., Molyneux, I., & Morice, A. H. (2011). Gastro-oesophageal reflux, eosinophilic airway inflammation and chronic cough. Respirology : official journal of the Asian Pacific Society of Respirology, 16(6), 994-999. https://doi.org/10.1111/j.1440-1843.2011.02010.xBackground and objective: Patients with eosinophilic airway inflammation (EAI) often show a therapeutic response to corticosteroids. Non-invasive methods of diagnosing EAI are potentially useful in guiding therapy, particularly in conditions such as... Read More about Gastro-oesophageal reflux, eosinophilic airway inflammation and chronic cough.
Effect of bitter tastants on human bronchi (2011)
Journal Article
Morice, A. H., Bennett, R. T., Chaudhry, M. A., Cowen, M. E., Griffin, S. C., & Loubani, M. (2011). Effect of bitter tastants on human bronchi. Nature Medicine, 17(7), 775. https://doi.org/10.1038/nm0711-775