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All Outputs (19)

M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication (2023)
Presentation / Conference Contribution
Moetazedian, A., Candeo, A., Bassi, A., Cox, L. R., Grover, L. M., & Poologasundarampillai, G. (2023, June). M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication. Presented at 2nd International Conference on Medical Devices: Materials, Mechanics and Manufacturing (ICMD3M 2023), Corfu, Greece

Microfluidics market is the fastest growing research area in the world, and they have shown much promise in biofabrication and 3D bioprinting of tissues and organs. However, microfluidics is conventionally produced using drawn-out and expensive litho... Read More about M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication.

Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline (2023)
Journal Article
Moetazedian, A., Candeo, A., Liu, S., Hughes, A., Nasrollahi, V., Saadat, M., …Poologasundarampillai, G. (2023). Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline. Advanced Healthcare Materials, 12(26), Article 2300636. https://doi.org/10.1002/adhm.202300636

Microfluidics have transformed diagnosis and screening in regenerative medicine. Recently, they are showing much promise in biofabrication. However, their adoption is inhibited by costly and drawn-out lithographic processes thus limiting progress. He... Read More about Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline.

Microfluidic-based 3D bioprinting for fabrication of helical fibres (2023)
Presentation / Conference Contribution
Moetazedian, A., Candeo, A., Bassi, A., Grover, L., Cox, L., & Poologasundarampillai, G. (2023, March). Microfluidic-based 3D bioprinting for fabrication of helical fibres. Poster presented at Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2023, Manchester

INTRODUCTION: 3D extrusion-based bioprinting has emerged as a promising technology for development of advanced and viable organs and tissues and functional 3D in vitro disease models [1,2]. However, these developments have failed to recapitulate the... Read More about Microfluidic-based 3D bioprinting for fabrication of helical fibres.

Microfluidic-based 3D bioprinting to fabricate blood vasculature (2023)
Presentation / Conference Contribution
Moetazedian, A., Cox, L., Grover, L., & Poologasundarampillai, G. (2022, June). Microfluidic-based 3D bioprinting to fabricate blood vasculature. Presented at UK Society for Biomaterials 22nd Annual Conference (UKSB 2022), University of Sheffield

Introduction:
The most substantial healthcare challenge facing the UK is the inevitable transition towards ageing population. Organ transplantation as the gold-standard treatment has saved many lives and millions of pounds for the NHS; however, ever... Read More about Microfluidic-based 3D bioprinting to fabricate blood vasculature.

Extra-wide deposition in extrusion additive manufacturing: A new convention for improved interlayer mechanical performance (2022)
Journal Article
Allum, J., Moetazedian, A., Gleadall, A., Mitchell, N., Marinopoulos, T., McAdam, I., …Silberschmidt, V. V. (2023). Extra-wide deposition in extrusion additive manufacturing: A new convention for improved interlayer mechanical performance. Additive Manufacturing, 61, Article 103334. https://doi.org/10.1016/j.addma.2022.103334

Recent studies have contested long-standing assumptions that mechanical anisotropy is caused by weak interlayer bonding and demonstrated that microscale geometry (the groove between extruded filaments) is the major cause of anisotropy in extrusion ad... Read More about Extra-wide deposition in extrusion additive manufacturing: A new convention for improved interlayer mechanical performance.

Investigation on corner precision at different corner angles in material extrusion additive manufacturing: An experimental and computational fluid dynamics analysis (2022)
Presentation / Conference Contribution
Mollah, M. T., Moetazedian, A., Gleadall, A., Yan, J., Alphonso, W. E., Comminal, R., Šeta, B., Lock, T., & Spangenberg, J. (2022, July). Investigation on corner precision at different corner angles in material extrusion additive manufacturing: An experimental and computational fluid dynamics analysis. Presented at 2022 International Solid Freeform Fabrication Symposium, University of Texas at Austin

This paper investigates the influence of different corner angles on microscale geometry in material extrusion additive manufacturing. Polylactic acid (PLA) was 3D-printed with corner angles of 15°, 30°, 45°, 60°, 75°, 90°, and 135° using Bowden and D... Read More about Investigation on corner precision at different corner angles in material extrusion additive manufacturing: An experimental and computational fluid dynamics analysis.

Hydrolytic degradation of polylactide in extrusion additive manufacturing (2022)
Thesis
Moetazedian, A. Hydrolytic degradation of polylactide in extrusion additive manufacturing. (Thesis). Loughborough University. https://hull-repository.worktribe.com/output/4864755

The combined use of material extrusion additive manufacturing (MEAM) and biodegradable polymers such as polylactide (PLA) is one of the most versatile and valuable manufacturing strategies for biomedical applications. MEAM enables rapid production of... Read More about Hydrolytic degradation of polylactide in extrusion additive manufacturing.

CONVEX microfluidic devices: a new microscale agile manufacturing pipeline for material extrusion additive manufacturing (2022)
Preprint / Working Paper
Moetazedian, A., Nasrollahi, V., Candeo, A., Cox, L., Grover, L., & Poologasundarampillai, G. CONVEX microfluidic devices: a new microscale agile manufacturing pipeline for material extrusion additive manufacturing

This study is the first to report the fabrication of complex microfluidic devices based on CONtinuously Varied EXtrusion (CONVEX) of extruded filament in material extrusion additive manufacturing (MEAM). A range of complex geometries and channel widt... Read More about CONVEX microfluidic devices: a new microscale agile manufacturing pipeline for material extrusion additive manufacturing.

Fracture mechanisms of additively manufactured polylactide: Effect of in vitro hydrolytic degradation (2022)
Journal Article
Moetazedian, A., Gleadall, A., & V Silberschmidt, V. (2022). Fracture mechanisms of additively manufactured polylactide: Effect of in vitro hydrolytic degradation. Engineering Fracture Mechanics, 269, Article 108572. https://doi.org/10.1016/j.engfracmech.2022.108572

This is the first study considering the effect of in vitro hydrolytic degradation at 37 °C on fracture mechanism of the most important aspect of additive manufacturing – the interface between layers. Specimens were tested transversely (failure betwee... Read More about Fracture mechanisms of additively manufactured polylactide: Effect of in vitro hydrolytic degradation.

Bulk-Material Bond Strength Exists in Extrusion Additive Manufacturing for a Wide Range of Temperatures, Speeds, and Layer Times (2021)
Journal Article
Moetazedian, A., Allum, J., Gleadall, A., & Silberschmidt, V. V. (2023). Bulk-Material Bond Strength Exists in Extrusion Additive Manufacturing for a Wide Range of Temperatures, Speeds, and Layer Times. 3D Printing and Additive Manufacturing, 10(3), 514-523. https://doi.org/10.1089/3dp.2021.0112

Do extrusion temperature, printing speed, and layer time affect mechanical performance of interlayer bonds in material extrusion additive manufacturing (MEAM)? The question is one of the main challenges in 3D printing of polymers. This article aims t... Read More about Bulk-Material Bond Strength Exists in Extrusion Additive Manufacturing for a Wide Range of Temperatures, Speeds, and Layer Times.

Discussion on the microscale geometry as the dominant factor for strength anisotropy in material extrusion additive manufacturing (2021)
Journal Article
Allum, J., Moetazedian, A., Gleadall, A., & Silberschmidt, V. V. (2021). Discussion on the microscale geometry as the dominant factor for strength anisotropy in material extrusion additive manufacturing. Additive Manufacturing, 48 part A, Article 102390. https://doi.org/10.1016/j.addma.2021.102390

This paper presents a discussion and interpretation of the findings in the review paper “Fused filament fabrication of polymer materials: A review of interlayer bond” by Xia Gao, Shunxin Qi, Xiao Kuang, Yunlan Su, Jing Li, Dujin Wang [Additive Manufa... Read More about Discussion on the microscale geometry as the dominant factor for strength anisotropy in material extrusion additive manufacturing.

MaTrEx AM: A new hybrid additive manufacturing process to selectively control mechanical properties (2021)
Journal Article
Moetazedian, A., Allum, J., Gleadall, A., Mele, E., & Silberschmidt, V. V. (2021). MaTrEx AM: A new hybrid additive manufacturing process to selectively control mechanical properties. Additive Manufacturing, 47, Article 102337. https://doi.org/10.1016/j.addma.2021.102337

This study is the first to demonstrate how mechanical and geometrical properties of polylactide (PLA) and acrylonitrile butadiene styrene (ABS) additively manufactured with material extrusion can be selectively tailored using a newly devised treatmen... Read More about MaTrEx AM: A new hybrid additive manufacturing process to selectively control mechanical properties.

Damage in extrusion additive manufactured biomedical polymer: Effects of testing direction and environment during cyclic loading (2021)
Journal Article
Moetazedian, A., Gleadall, A., Mele, E., & Silberschmidt, V. V. (2021). Damage in extrusion additive manufactured biomedical polymer: Effects of testing direction and environment during cyclic loading. Journal of the mechanical behavior of biomedical materials, 118, Article 104397. https://doi.org/10.1016/j.jmbbm.2021.104397

Although biodegradable polymers were widely researched, this is the first study considering the effect of combined testing environments and cyclic loading on the most important aspect related to additive manufacturing: the interfacial bond between de... Read More about Damage in extrusion additive manufactured biomedical polymer: Effects of testing direction and environment during cyclic loading.

Mechanical performance of 3D printed polylactide during degradation (2020)
Journal Article
Moetazedian, A., Gleadall, A., Han, X., Ekinci, A., Mele, E., & Silberschmidt, V. V. (2021). Mechanical performance of 3D printed polylactide during degradation. Additive Manufacturing, 38, Article 101764. https://doi.org/10.1016/j.addma.2020.101764

Although widely-used biodegradable polymers have been extensively studied for conventional manufacturing processes, this is the first study considering the effect of interfacial bonds between extruded filaments – the most important aspect related to... Read More about Mechanical performance of 3D printed polylactide during degradation.

Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading (2020)
Presentation / Conference Contribution
Moetazedian, A., Gleadall, A., Mele, E., & Silberschmidt, V. V. (2020, June). Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading. Presented at 1st Virtual European Conference on Fracture, Online

With a general cautious attitude regarding the anisotropic properties of upright 3D-printed parts, there is a lack of fundamental understanding of behavior of 3D-printed polymers under cyclic loading condition, which is more representative of real-li... Read More about Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading.

CONVEX (CONtinuously Varied EXtrusion): A new scale of design for additive manufacturing (2020)
Journal Article
Moetazedian, A., Budisuharto, A. S., Silberschmidt, V. V., & Gleadall, A. (2021). CONVEX (CONtinuously Varied EXtrusion): A new scale of design for additive manufacturing. Additive Manufacturing, 37, Article 101576. https://doi.org/10.1016/j.addma.2020.101576

This study introduces a new microscale design approach, CONVEX, based on the idea of CONtinuously Varying EXtrusion widths of deposited filaments in material extrusion additive manufacturing (MEAM). The CONVEX design approach breaks free from the tra... Read More about CONVEX (CONtinuously Varied EXtrusion): A new scale of design for additive manufacturing.

Interlayer bonding has bulk-material strength in extrusion additive manufacturing: New understanding of anisotropy (2020)
Journal Article
Allum, J., Moetazedian, A., Gleadall, A., & Silberschmidt, V. V. (2020). Interlayer bonding has bulk-material strength in extrusion additive manufacturing: New understanding of anisotropy. Additive Manufacturing, 34, Article 101297. https://doi.org/10.1016/j.addma.2020.101297

This study demonstrates that the interface between layers in 3D-printed polylactide has strength of the bulk filament. Specially designed 3D-printed tensile specimens were developed to test mechanical properties in the direction of the extruded filam... Read More about Interlayer bonding has bulk-material strength in extrusion additive manufacturing: New understanding of anisotropy.

Effect of environment on mechanical properties of 3D printed polylactide for biomedical applications (2019)
Journal Article
Moetazedian, A., Gleadall, A., Han, X., & Silberschmidt, V. V. (2020). Effect of environment on mechanical properties of 3D printed polylactide for biomedical applications. Journal of the mechanical behavior of biomedical materials, 102, Article 103510. https://doi.org/10.1016/j.jmbbm.2019.103510

In this study, the importance of the testing environment for correct assessment of tensile strength of polylactide (PLA) is investigated. A novel design of tensile specimen was developed to test the anisotropic mechanical properties of additively man... Read More about Effect of environment on mechanical properties of 3D printed polylactide for biomedical applications.