All Outputs (27)

Biomarker Driven Antifungal Stewardship (BioDriveAFS) in acute leukaemia—a multi-centre randomised controlled trial to assess clinical and cost effectiveness: a study protocol for a randomised controlled trial (2024)
Journal Article
Flett, L., Abdelatif, R., Akhtar Baz, S., Brady, S., Corbacho, B., Common, K., Cowling, A., Fairhurst, C., Fitzmaurice, E., Gandhi, S., Hilton, A., Hope, W., Howard, A., Laycock, J., Lillie, P., Mitchell, G., Parker, A., Peel, M., Sheard, L., Sneddon, J., …Barlow, G. (2024). Biomarker Driven Antifungal Stewardship (BioDriveAFS) in acute leukaemia—a multi-centre randomised controlled trial to assess clinical and cost effectiveness: a study protocol for a randomised controlled trial. Trials, 25(1), Article 427. https://doi.org/10.1186/s13063-024-08272-w

BACKGROUND: Acute leukaemias (AL) are life-threatening blood cancers that can be potentially cured with treatment involving myelosuppressive, multiagent, intensive chemotherapy (IC). However, such treatment is associated with a risk of serious infect... Read More about Biomarker Driven Antifungal Stewardship (BioDriveAFS) in acute leukaemia—a multi-centre randomised controlled trial to assess clinical and cost effectiveness: a study protocol for a randomised controlled trial.

What really is nontokenistic fully inclusive patient and public involvement/engagement in research? (2024)
Journal Article
Hilton, A., Megson, M., Aryankhesal, A., Blake, J., Rook, G., Irvine, A., …TIMES programme team. (2024). What really is nontokenistic fully inclusive patient and public involvement/engagement in research?. Health Expectations, 27(2), Article e14012. https://doi.org/10.1111/hex.14012

Patient and public involvement and engagement (PPIE) is critically important in healthcare research. A useful starting point for researchers to understand the scope of PPIE is to review the definition from the National Institute for Health and Care R... Read More about What really is nontokenistic fully inclusive patient and public involvement/engagement in research?.

Exploring the interplay between dementia, multiple health conditions and couplehood: A qualitative evidence review and meta-ethnography (2023)
Journal Article
Dunn, R., Wolverson, E., & Hilton, A. (2024). Exploring the interplay between dementia, multiple health conditions and couplehood: A qualitative evidence review and meta-ethnography. Dementia, 23(1), 41-68. https://doi.org/10.1177/14713012231214017

Background: On average, people with dementia live with 4.6 additional health conditions. Additionally, two thirds of carers of people with dementia are spouses, and are also likely to live with multimorbidity, given that older age is strongly associa... Read More about Exploring the interplay between dementia, multiple health conditions and couplehood: A qualitative evidence review and meta-ethnography.

Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice (2023)
Journal Article
Aryankhesal, A., Blake, J., Wong, G., Megson, M., Briscoe, S., Allan, L., Broomfield, N., Eastwood, Z., Greene, L., Hilton, A., Killett, A., Lazar, A., Litherland, R., Livingston, G., Maidment, I., Reeve, J., Rook, G., Scott, S., Un, J., van Horik, J., & Fox, C. (online). Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice. The British journal of general practice : the journal of the Royal College of General Practitioners, https://doi.org/10.3399/BJGP.2023.0171

Background
Sleep disturbance (SD) is a prevalent condition among people living with dementia (PLwD) or mild cognitive impairment (MCI). Its assessment and management within primary care is complex due to the comorbidities, older age and cognitive im... Read More about Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice.

The “vicious circle” of chronic cough: The patient experience – qualitative synthesis (2023)
Journal Article
Brindle, K., Morice, A., Carter, N., Sykes, D., Zhang, M., & Hilton, A. (2023). The “vicious circle” of chronic cough: The patient experience – qualitative synthesis. ERJ Open Research, 9(3), Article 00094-2023. https://doi.org/10.1183/23120541.00094-2023

Aim The aim of this study was to systematically search and synthesise findings from peer-reviewed qualitative studies describing the experiences of those living with chronic cough. Methods A systematic search was conducted to identify all studies tha... Read More about The “vicious circle” of chronic cough: The patient experience – qualitative synthesis.

Understanding primary care diagnosis and management of sleep disturbance for people with dementia or mild cognitive impairment: a realist review protocol (2022)
Journal Article
Greene, L., Aryankhesal, A., Megson, M., Blake, J., Wong, G., Briscoe, S., Hilton, A., Killett, A., Reeve, J., Allan, L., Ballard, C., Broomfield, N., van Horik, J., Khondoker, M., Lazar, A., Litherland, R., Livingston, G., Maidment, I., Medina-Lara, A., Rook, G., …Fox, C. (2022). Understanding primary care diagnosis and management of sleep disturbance for people with dementia or mild cognitive impairment: a realist review protocol. BMJ open, 12(11), Article e067424. https://doi.org/10.1136/bmjopen-2022-067424

INTRODUCTION: The increasingly ageing population is associated with greater numbers of people living with dementia (PLwD) and mild cognitive impairment (MCI). There are an estimated 55 million PLwD and approximately 6% of people over 60 years of age... Read More about Understanding primary care diagnosis and management of sleep disturbance for people with dementia or mild cognitive impairment: a realist review protocol.

Conceptualising comorbidity and multimorbidity in dementia: A scoping review and syndemic framework (2022)
Journal Article
Dunn, R., Clayton, E., Wolverson, E., & Hilton, A. (2022). Conceptualising comorbidity and multimorbidity in dementia: A scoping review and syndemic framework. Journal of Multimorbidity and Comorbidity, 12, https://doi.org/10.1177/26335565221128432

Background
Older people and people with dementia experience a high prevalence of multiple health conditions. The terms ‘comorbidity’ and ‘multimorbidity’ are often used interchangeably to describe this, however there are key conceptual differences b... Read More about Conceptualising comorbidity and multimorbidity in dementia: A scoping review and syndemic framework.

Prevention of alcohol related harm though preconception care: A scoping review of barriers and enablers (2022)
Journal Article
Smith, L., Hilton, A., Walker, J., Alfred, L., Ahankari, A., & Schölin, L. (2022). Prevention of alcohol related harm though preconception care: A scoping review of barriers and enablers. Dialogues in Health, 1, Article 100040. https://doi.org/10.1016/j.dialog.2022.100040

Objective: To understand the perspectives of healthcare practitioners and women of reproductive age regarding addressing prevention of an alcohol exposed pregnancy before conception. Methods: A scoping review of mixed methods, qualitative and quantit... Read More about Prevention of alcohol related harm though preconception care: A scoping review of barriers and enablers.

Rapid realist review of the role of community pharmacy in the public health response to COVID-19 (2021)
Journal Article
Maidment, I., Young, E., MacPhee, M., Booth, A., Zaman, H., Breen, J., …Wong, G. (2021). Rapid realist review of the role of community pharmacy in the public health response to COVID-19. BMJ open, 11(6), Article e050043. https://doi.org/10.1136/bmjopen-2021-050043

Introduction Community pharmacists and their teams have remained accessible to the public providing essential services despite immense pressures during the COVID-19 pandemic. They have successfully expanded the influenza vaccination programme and are... Read More about Rapid realist review of the role of community pharmacy in the public health response to COVID-19.

Development and validity testing of a type 1 diabetes resource for 10-19-years old adolescents in China (2021)
Journal Article
Zhao, X., Hilton, A., Watson, R., & Chen, Y. (in press). Development and validity testing of a type 1 diabetes resource for 10-19-years old adolescents in China. Journal of Pediatric Nursing, https://doi.org/10.1016/j.pedn.2021.03.029

Purpose: This phase 1 study aimed to develop a Type 1 diabetes (T1DM) educational resource for adolescents (10–19 years) in China, and to test its validity for improving diabetes knowledge, self-efficacy and adherence. Design and methods: This phase... Read More about Development and validity testing of a type 1 diabetes resource for 10-19-years old adolescents in China.

Dignity, well-being and identity: A qualitative study of older people's interpretations of how healthcare workers speak to them (2020)
Journal Article
Draper, P., & Hilton, A. (2021). Dignity, well-being and identity: A qualitative study of older people's interpretations of how healthcare workers speak to them. Nursing older people, 33(1), https://doi.org/10.7748/NOP.2020.E1261

© RCN Publishing Company Limited 2021. Background The initial interaction between an older person and a nurse, and how the older person interprets this interaction, is important and sometimes overlooked. Evidence suggests that the way healthcare work... Read More about Dignity, well-being and identity: A qualitative study of older people's interpretations of how healthcare workers speak to them.

MEDREV (pharmacy-health psychology intervention in people living with dementia with behaviour that challenges): The feasibility of measuring clinical outcomes and costs of the intervention (2020)
Journal Article
Maidment, I. D., Barton, G., Campbell, N., Shaw, R., Seare, N., Fox, C., Iliffe, S., Randle, E., Hilton, A., Brown, G., Barnes, N., Wilcock, J., Gillespie, S., & Damery, S. (2020). MEDREV (pharmacy-health psychology intervention in people living with dementia with behaviour that challenges): The feasibility of measuring clinical outcomes and costs of the intervention. BMC health services research, 20(1), Article 157. https://doi.org/10.1186/s12913-020-5014-0

© 2020 The Author(s). Background: People living with dementia in care homes frequently exhibit "behaviour that challenges". Anti-psychotics are used to treat such behaviour, but are associated with significant morbidity. This study researched the fea... Read More about MEDREV (pharmacy-health psychology intervention in people living with dementia with behaviour that challenges): The feasibility of measuring clinical outcomes and costs of the intervention.

The paramedic experience of the prescribing journey (2019)
Journal Article
Hilton, A., Graham, C. J., Taylor, C., Ali, S. A. R., & Faulkes, E. S. (2019). The paramedic experience of the prescribing journey. Journal of prescribing practice, 1(4), 194-196. https://doi.org/10.12968/jprp.2019.1.4.194

This article gives an overview of the journey of four paramedic advanced practitioners working towards a non-medical prescribing qualification. The legislation was changed in April 2018 to allow advanced paramedics to undertake a suitable validated h... Read More about The paramedic experience of the prescribing journey.

Medication review plus person-centred care: a feasibility study of a pharmacy-health psychology dual intervention to improve care for people living with dementia (2018)
Journal Article
Maidment, I. D., Damery, S., Campbell, N., Seare, N., Fox, C., Iliffe, S., Hilton, A., Brown, G., Barnes, N., Wilcock, J., Randle, E., Gillespie, S., Barton, G., & Shaw, R. (2018). Medication review plus person-centred care: a feasibility study of a pharmacy-health psychology dual intervention to improve care for people living with dementia. BMC Psychiatry, 18(1), Article 340. https://doi.org/10.1186/s12888-018-1907-4

Background
“Behaviour that Challenges” is common in people living with dementia, resident in care homes and historically has been treated with anti-psychotics. However, such usage is associated with 1800 potentially avoidable deaths annually in the U... Read More about Medication review plus person-centred care: a feasibility study of a pharmacy-health psychology dual intervention to improve care for people living with dementia.

The structure of mentors' behaviour in clinical nursing education: Confirmatory factor analysis (2018)
Journal Article
Chen, Y., Watson, R., & Hilton, A. (2018). The structure of mentors' behaviour in clinical nursing education: Confirmatory factor analysis. Nurse education today, 68, 192-197. https://doi.org/10.1016/j.nedt.2018.06.018

Aims: To study if a three-factor structure of mentors' behaviour identified through exploratory factor analysis could be confirmed in a dataset assessing mentors' performance using structural equation modelling. Background: To measure mentor's behavi... Read More about The structure of mentors' behaviour in clinical nursing education: Confirmatory factor analysis.

Exploring the evidence base for how people with dementia and their informal carers manage their medication in the community : a mixed studies review (2017)
Journal Article
Hilton, A., Aston, L., Maidment, I., Moutela, T., & Shaw, R. (2017). Exploring the evidence base for how people with dementia and their informal carers manage their medication in the community : a mixed studies review. BMC Geriatrics, 17(1), Article ARTN 242. https://doi.org/10.1186/s12877-017-0638-6

Background: Little is known about the general medicines management issues for people with dementia living in the community. This review has three aims: firstly to explore and evaluate the international literature on how people with dementia manage me... Read More about Exploring the evidence base for how people with dementia and their informal carers manage their medication in the community : a mixed studies review.

Challenge Demcare: management of challenging behaviour in dementia at home and in care homes – development, evaluation and implementation of an online individualised intervention for care homes; and a cohort study of specialist community mental health care for families (2017)
Journal Article
Moniz-Cook, E., Hart, C., Woods, B., Whitaker, C., James, I., Russell, I., Edwards, R. T., Hilton, A., Orrell, M., Campion, P., Stokes, G., Jones, R. S., Bird, M., Poland, F., & Manthorpe, J. (2017). Challenge Demcare: management of challenging behaviour in dementia at home and in care homes – development, evaluation and implementation of an online individualised intervention for care homes; and a cohort study of specialist community mental health care for families. Programme Grants for Applied Research, 5(15), 1-290. https://doi.org/10.3310/pgfar05150

Background

Dementia with challenging behaviour (CB) causes significant distress for caregivers and the person with dementia. It is associated with breakdown of care at home and disruption in care homes. Challenge Demcare aimed to assist care home... Read More about Challenge Demcare: management of challenging behaviour in dementia at home and in care homes – development, evaluation and implementation of an online individualised intervention for care homes; and a cohort study of specialist community mental health care for families.

A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist (2017)
Journal Article
Maidment, I. D., Aston, L., Moutela, T., Fox, C. G., & Hilton, A. (2017). A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist. Health Expectations, 20(5), 929-942. https://doi.org/10.1111/hex.12534

Background The prevalence of dementia is increasing rapidly. People with dementia may be prescribed complex medication regimens, which may be challenging for them and any carers involved to safely manage. Objective To describe and understand the key... Read More about A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist.

Managing constipation in adults with co-morbidities (2016)
Journal Article
Gardiner, A., & Hilton, A. (2016). Managing constipation in adults with co-morbidities. Independent nurse, 2016(10), 21-25. https://doi.org/10.12968/indn.2016.10.21

Constipation can be described in a number of ways but in general it is related to straining, reduced frequency of defecation and/or a sensation of incomplete bowel emptying. The ability of the bowel to empty is related to the effectiveness of colonic... Read More about Managing constipation in adults with co-morbidities.

Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy-health psychology intervention feasibility study (2016)
Journal Article
Maidment, I. D., Shaw, R. L., Killick, K., Damery, S., Hilton, A., Wilcock, J., Barnes, N., Brown, G., Gillespie, S., Fox, C., Barton, G., Iliffe, S., & Seare, N. (2016). Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy-health psychology intervention feasibility study. BMJ open, 6(3), e010279. https://doi.org/10.1136/bmjopen-2015-010279

Introduction The inappropriate use of antipsychotics in people with dementia for behaviour that challenges is associated with an estimated 1800 deaths annually. However, solely focusing on antipsychotics may transfer prescribing to other equally dang... Read More about Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy-health psychology intervention feasibility study.