All Outputs (21)

Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLoS ONE, 19(3 March), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence (2019)
Journal Article
Nickolay, T., Nichols, S., Ingle, L., & Hoye, A. (2020). Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence. Current Cardiology Reviews, 16(3), 212-220. https://doi.org/10.2174/1573403X15666190819144336

Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion. Flow through these channels is driven by a pressure gradient between the donor and the occluded artery. Concomitant with increased collateral flow is an... Read More about Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence.

Multi-disciplinary palliative care is effective in people with symptomatic heart failure: A systematic review and narrative synthesis (2019)
Journal Article
Datla, S., Verberkt, C. A., Hoye, A., Janssen, D. J. A., & Johnson, M. J. (2019). Multi-disciplinary palliative care is effective in people with symptomatic heart failure: A systematic review and narrative synthesis. Palliative medicine, 33(8), 1003-1016. https://doi.org/10.1177/0269216319859148

Background: Despite recommendations, people with heart failure have poor access to palliative care. Aim: To identify the evidence in relation to palliative care for people with symptomatic heart failure. Design: Systematic review and narrative synthe... Read More about Multi-disciplinary palliative care is effective in people with symptomatic heart failure: A systematic review and narrative synthesis.

Acute coronary syndromes, platelets and the endothelium (2019)
Thesis
Rossington, J. A. (2019). Acute coronary syndromes, platelets and the endothelium. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222365

ABSTRACT
Background: Acute coronary syndromes (ACS) are medical emergencies. Platelet and endothelial function are fundamental to the pathophysiology; and implicated in secondary conditions such as no reflow (NR). Guidelines support the administrati... Read More about Acute coronary syndromes, platelets and the endothelium.

Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial (2019)
Journal Article
Zaman, A., de Winter, R. J., Kogame, N., Chang, C. C., Modolo, R., Spitzer, E., Tonino, P., Hofma, S., Zurakowski, A., Smits, P. C., Prokopczuk, J., Moreno, R., Choudhury, A., Petrov, I., Cequier, A., Kukreja, N., Hoye, A., Iniguez, A., Ungi, I., Serra, A., …Serruys, P. W. (2019). Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial. Lancet, 393(10175), 987-997. https://doi.org/10.1016/S0140-6736%2818%2932467-X

Background: Supraflex is a sirolimus-eluting stent with a biodegradable polymer coating and ultra-thin struts. We aimed to compare Supraflex with the standard of care, Xience, an everolimus-eluting stent with a durable polymer coating, regarding clin... Read More about Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial.

Cardiogoniometry compared to fractional flow reserve at identifying physiologically significant coronary stenosis: The Cardioflow Study (2018)
Journal Article
Brown, O. I., Clark, A. L., Chelliah, R., Davison, B. J., Mather, A. N., Cunnington, M. S., John, J., Alahmar, A., Oliver, R., Aznaouridis, K., & Hoye, A. (2018). Cardiogoniometry compared to fractional flow reserve at identifying physiologically significant coronary stenosis: The Cardioflow Study. Cardiovascular Engineering and Technology, 9(3), 439-446. https://doi.org/10.1007/s13239-018-0354-1

Cardiogoniometry (CGM) is method of 3-dimensional electrocardiographic assessment which has been shown to identify patients with angiographically defined, stable coronary artery disease (CAD). However, angiographic evidence of CAD, does not always co... Read More about Cardiogoniometry compared to fractional flow reserve at identifying physiologically significant coronary stenosis: The Cardioflow Study.

The HF-CGM study: An analysis of cardiogoniometric axes in patients with cardiac resynchronization therapy (2017)
Journal Article
Clark, A. L., Hoye, A., Beddoes, G., Nikolaidou, T., & Brown, O. I. (2018). The HF-CGM study: An analysis of cardiogoniometric axes in patients with cardiac resynchronization therapy. IEEE transactions on bio-medical engineering / Bio-medical Engineering Group, 65(8), 1711-1716. https://doi.org/10.1109/TBME.2017.2769060

Goal: The HF-CGM is a proof-of-principle study to investigate whether cardiogoniometry (CGM), a three-dimensional electrocardiographic method, can differentiate between pacing modes in patients with cardiac resynchronization therapy (CRT). Methods: A... Read More about The HF-CGM study: An analysis of cardiogoniometric axes in patients with cardiac resynchronization therapy.

Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction (2017)
Journal Article
Sze, S., Zhang, J., Pellicori, P., Morgan, D., Hoye, A., & Clark, A. L. (2017). Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction. Clinical Research in Cardiology, 106(7), 533-541. https://doi.org/10.1007/s00392-017-1082-5

© 2017, Springer-Verlag Berlin Heidelberg. Background: Frailty and malnutrition are common in patients with heart failure (HF), and are associated with adverse outcomes. We studied the prognostic value of three malnutrition and three frailty indices... Read More about Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction.

Influence of case definition on incidence and outcome of acute coronary syndromes (2016)
Journal Article
Torabi, A., Cleland, J. G. F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Clark, A. L., & Rigby, A. (2016). Influence of case definition on incidence and outcome of acute coronary syndromes. Open heart, 3(2), e000487. https://doi.org/10.1136/openhrt-2016-000487

© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected. We compared case ascertainment rates for ACS and myocardial infar... Read More about Influence of case definition on incidence and outcome of acute coronary syndromes.

Percutaneous device closure of paravalvular leak (2016)
Journal Article
Calvert, P. A., Northridge, D. B., Malik, I. S., Shapiro, L., Ludman, P., Qureshi, S. A., Mullen, M., Henderson, R., Turner, M., Been, M., Walsh, K. P., Casserly, I., Morrison, L., Walker, N. L., Thomson, J., Spence, M. S., Mahadevan, V. S., Hoye, A., Maccarthy, P. A., Daniels, M. J., …Hildick-Smith, D. (2016). Percutaneous device closure of paravalvular leak. Circulation, 134(13), 934-944. https://doi.org/10.1161/CIRCULATIONAHA.116.022684

Background: Paravalvular leak (PVL) occurs in 5% to 17% of patients following surgical valve replacement. Percutaneous device closure represents an alternative to repeat surgery. Methods: All UK and Ireland centers undertaking percutaneous PVL closur... Read More about Percutaneous device closure of paravalvular leak.

Dedicated Bifurcation Stent for the Treatment of Bifurcation Lesions InvolvingLarge Side Branches: Outcomes From the Tryton Confirmatory Study (2016)
Journal Article
Généreux, P., Kumsars, I., Schneider, J. E., Lesiak, M., Redfors, B., Cornelis, K., Selmon, M. R., Dens, J., Hoye, A., Metzger, D. C., Muyldermans, L., Slagboom, T., Francese, D. P., Ayele, G. M., Laak, L. L., Bartorelli, A. L., Cutlip, D. E., Kaplan, A. V., & Leon, M. B. (2016). Dedicated Bifurcation Stent for the Treatment of Bifurcation Lesions InvolvingLarge Side Branches: Outcomes From the Tryton Confirmatory Study. JACC: Cardiovascular Interventions, 9(13), 1338-1346. https://doi.org/10.1016/j.jcin.2016.03.042

Objectives: The aim of this study was to prospectively study and confirm the safety and efficacy of the Tryton Side Branch Stent in the treatment of coronary artery bifurcations involving large side branches (SBs). Background The TRYTON Pivotal rando... Read More about Dedicated Bifurcation Stent for the Treatment of Bifurcation Lesions InvolvingLarge Side Branches: Outcomes From the Tryton Confirmatory Study.

Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization (2016)
Journal Article
Ladwiniec, A., Ettelaie, C., Cunnington, M. S., Rossington, J., Thackray, S., Alamgir, F., & Hoye, A. (2016). Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization. Coronary Artery Disease, 27(4), 287-294. https://doi.org/10.1097/mca.0000000000000360

Objectives: In the presence of a chronically occluded coronary artery, the collateral circulation matures by a process of arteriogenesis; however, there is considerable variation between individuals in the functional capacity of that collateral netwo... Read More about Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization.

Chronic total coronary occlusions, distal collateral supply and implications of recanalisation (2016)
Thesis
Ladwiniec, A. (2016). Chronic total coronary occlusions, distal collateral supply and implications of recanalisation. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218216

The optimal treatment for patients with a chronic total coronary occlusion (CTO) is controversial, both in terms of the decision whether to revascularise and with respect to the physiological effect of recanalisation on revascularisation strategy.... Read More about Chronic total coronary occlusions, distal collateral supply and implications of recanalisation.

Systematic review and meta-analysis of optimal P2Y₁₂ blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome (2016)
Journal Article
Rossington, J. A., Brown, O. I., & Hoye, A. (2016). Systematic review and meta-analysis of optimal P2Y₁₂ blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome. Open heart, 3(1), e000296. https://doi.org/10.1136/openhrt-2015-000296

Background: Patients with diabetes are at increased risk of acute coronary syndromes (ACS) and their mortality and morbidity outcomes are significantly worse following ACS events, independent of other comorbidities. This systematic review sought to e... Read More about Systematic review and meta-analysis of optimal P2Y₁₂ blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome.

Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization (2016)
Journal Article
Ladwiniec, A., Cunnington, M. S., Rossington, J., Thackray, S., Alamgir, F., & Hoye, A. (2016). Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization. Catheterization and Cardiovascular Interventions, 87(6), 1071-1079. https://doi.org/10.1002/ccd.26392

Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel... Read More about Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization.

Medical therapy, percutaneous coronary intervention and prognosis in patients with chronic total occlusions (2015)
Journal Article
Ladwiniec, A., Allgar, V., Thackray, S., Alamgir, F., & Hoye, A. (2015). Medical therapy, percutaneous coronary intervention and prognosis in patients with chronic total occlusions. Heart, 101(23), 1907-1914. https://doi.org/10.1136/heartjnl-2015-308181

Objective There is little published data reporting outcomes for those found to have a chronic total coronary occlusion (CTO) that is electively treated medically versus those treated by percutaneous coronary intervention (PCI). We sought to compare l... Read More about Medical therapy, percutaneous coronary intervention and prognosis in patients with chronic total occlusions.

The haemodynamic effects of collateral donation to a chronic total occlusion : implications for patient management (2015)
Journal Article
Ladwiniec, A., & Hoye, A. (2015). The haemodynamic effects of collateral donation to a chronic total occlusion : implications for patient management. International journal of cardiology, 198, 159-166. https://doi.org/10.1016/j.ijcard.2015.06.174

Physiological lesion assessment in the form of Fractional Flow Reserve (FFR) is now well established for the purpose of guiding multi-vessel revascularization. Chronic total coronary occlusions are frequently associated with multi-vessel disease and... Read More about The haemodynamic effects of collateral donation to a chronic total occlusion : implications for patient management.

Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve (2015)
Journal Article
Ladwiniec, A., Cunnington, M. S., Rossington, J., Mather, A. N., Alahmar, A., Oliver, R. M., Nijjer, S. S., Davies, J. E., Thackray, S., Alamgir, F., & Hoye, A. (2015). Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve. Circulation. Cardiovascular interventions, 8(4), Article UNSP e002219. https://doi.org/10.1161/CIRCINTERVENTIONS.114.002219

Background— The presence of a concomitant chronic total coronary occlusion (CTO) and a large collateral contribution might alter the fractional flow reserve (FFR) of an interrogated vessel, rendering the FFR unreliable at predicting ischemia should t... Read More about Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve.

Clinical indications for intravascular ultrasound imaging (2010)
Journal Article
Bourantas, C. V., Naka, K. K., Garg, S., Thackray, S., Papadopoulos, D., Alamgir, F. M., Hoye, A., & Michalis, L. K. (2010). Clinical indications for intravascular ultrasound imaging. Echocardiography, 27(10), 1282-1290. https://doi.org/10.1111/j.1540-8175.2010.01259.x

Intravascular ultrasound (IVUS) is a catheter-based imaging modality, which provides high resolution cross-sectional images of the coronary arteries. Unlike angiography, which displays only the opacified luminal silhouette, IVUS permits imaging of bo... Read More about Clinical indications for intravascular ultrasound imaging.