All Outputs (20)

Are profiles of social, cultural, and economic capital related to living well with dementia? Longitudinal findings from the IDEAL programme (2022)
Journal Article
Sabatini, S., Martyr, A., Gamble, L. D., Jones, I. R., Collins, R., Matthews, F. E., …Clare, L. (2023). Are profiles of social, cultural, and economic capital related to living well with dementia? Longitudinal findings from the IDEAL programme. Social science & medicine, 317, Article 115603. https://doi.org/10.1016/j.socscimed.2022.115603

Rationale: Research exploring social, cultural, and economic capital among people with dementia is scarce. Objective: We describe levels of social, cultural, and economic capital in people with dementia at baseline and levels of social and cultural c... Read More about Are profiles of social, cultural, and economic capital related to living well with dementia? Longitudinal findings from the IDEAL programme.

Autism incidence and spatial analysis in more than 7 million pupils in English schools: a retrospective, longitudinal, school registry study (2022)
Journal Article
Roman-Urrestarazu, A., Yang, J. C., van Kessel, R., Warrier, V., Dumas, G., Jongsma, H., …Brayne, C. (2022). Autism incidence and spatial analysis in more than 7 million pupils in English schools: a retrospective, longitudinal, school registry study. The Lancet Child & Adolescent Health, 6(12), 857-868. https://doi.org/10.1016/S2352-4642%2822%2900247-4

Background: Understanding how certain factors affect autism incidence can help to identify inequities in diagnostic access. We aimed to investigate the incidence of autism in England as a function of geography and sociodemographics, examining spatial... Read More about Autism incidence and spatial analysis in more than 7 million pupils in English schools: a retrospective, longitudinal, school registry study.

Impact of COVID-19 policies on perceptions of loneliness in people aged 75 years and over in the cognitive function and aging study (CFAS II) (2022)
Journal Article
Richardson, C. D., Roscoe, H., Green, E., Brooks, R., Barnes, L., Matthews, F. E., & Brayne, C. (2023). Impact of COVID-19 policies on perceptions of loneliness in people aged 75 years and over in the cognitive function and aging study (CFAS II). Journal of the American Geriatrics Society, 71(2), 463-473. https://doi.org/10.1111/jgs.18099

Background: The COVID-19 pandemic and associated social distancing measures have profoundly impacted society and social contact patterns, with older people disproportionately affected. Concerns have been raised about a resulting pandemic of lonelines... Read More about Impact of COVID-19 policies on perceptions of loneliness in people aged 75 years and over in the cognitive function and aging study (CFAS II).

Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis (2022)
Journal Article
Peters, R., Xu, Y., Fitzgerald, O., Aung, H. L., Beckett, N., Bulpitt, C., Chalmers, J., Forette, F., Gong, J., Harris, K., Humburg, P., Matthews, F. E., Staessen, J. A., Thijs, L., Tzourio, C., Warwick, J., Woodward, M., & Anderson, C. S. (2022). Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis. European Heart Journal, 43(48), 4980-4990. https://doi.org/10.1093/eurheartj/ehac584

Aims Observational studies indicate U-shaped associations of blood pressure (BP) and incident dementia in older age, but randomized controlled trials of BP-lowering treatment show mixed results on this outcome in hypertensive patients. A pooled indiv... Read More about Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis.

Longitudinal Predictors of Informant-Rated Involvement of People with Dementia in Everyday Decision-Making: Findings from the IDEAL Program (2022)
Journal Article
Sabatini, S., Martyr, A., Gamble, L. D., Collins, R., Matthews, F. E., Morris, R. G., …Clare, L. (2023). Longitudinal Predictors of Informant-Rated Involvement of People with Dementia in Everyday Decision-Making: Findings from the IDEAL Program. Journal of applied gerontology, 42(2), 290-301. https://doi.org/10.1177/07334648221128558

The extent to which people with dementia are involved in everyday decision-making is unclear. We explored informant-rated involvement of people with dementia in everyday decision-making over 2 years and whether functional, behavioral, and psychologic... Read More about Longitudinal Predictors of Informant-Rated Involvement of People with Dementia in Everyday Decision-Making: Findings from the IDEAL Program.

Explaining the deprivation gap in COVID-19 mortality rates: A decomposition analysis of geographical inequalities in England (2022)
Journal Article
Albani, V., Welsh, C. E., Brown, H., Matthews, F. E., & Bambra, C. (2022). Explaining the deprivation gap in COVID-19 mortality rates: A decomposition analysis of geographical inequalities in England. Social science & medicine, 311, Article 115319. https://doi.org/10.1016/j.socscimed.2022.115319

One of the most consistent and worrying features of the COVID-19 pandemic globally has been the disproportionate burden of the epidemic in the most deprived areas. Most of the literature so far though has focused on estimating the extent of these ine... Read More about Explaining the deprivation gap in COVID-19 mortality rates: A decomposition analysis of geographical inequalities in England.

Inequalities in the evolution of the COVID-19 pandemic: an ecological study of inequalities in mortality in the first wave and the effects of the first national lockdown in England (2022)
Journal Article
Welsh, C., Albani, V., Matthews, F., & Bambra, C. (2022). Inequalities in the evolution of the COVID-19 pandemic: an ecological study of inequalities in mortality in the first wave and the effects of the first national lockdown in England. BMJ open, 12(8), Article e058658. https://doi.org/10.1136/bmjopen-2021-058658

Objectives To examine how ecological inequalities in COVID-19 mortality rates evolved in England, and whether the first national lockdown impacted them. This analysis aimed to provide evidence for important lessons to inform public health planning to... Read More about Inequalities in the evolution of the COVID-19 pandemic: an ecological study of inequalities in mortality in the first wave and the effects of the first national lockdown in England.

Profiles of social, cultural, and economic capital as longitudinal predictors of stress, positive experiences of caring, and depression among spousal carers of people with dementia (2022)
Journal Article
Sabatini, S., Martyr, A., Gamble, L. D., Jones, I. R., Collins, R., Matthews, F., …Clare, L. (2023). Profiles of social, cultural, and economic capital as longitudinal predictors of stress, positive experiences of caring, and depression among spousal carers of people with dementia. Aging and Mental Health, 27(7), 1335-1343. https://doi.org/10.1080/13607863.2022.2098920

Objective: We explored (1) social, cultural, and economic capital in spousal carers of people with dementia; (2) profiles of carers with different levels of capital; (3) whether the identified profiles differ in levels of stress and positive experien... Read More about Profiles of social, cultural, and economic capital as longitudinal predictors of stress, positive experiences of caring, and depression among spousal carers of people with dementia.

"Living Well" Trajectories Among Family Caregivers of People With Mild-to-Moderate Dementia in the IDEAL Cohort (2022)
Journal Article
Clare, L., Gamble, L. D. D., Martyr, A., Sabatini, S., Nelis, S. M., Quinn, C., …Matthews, F. E. (2022). "Living Well" Trajectories Among Family Caregivers of People With Mild-to-Moderate Dementia in the IDEAL Cohort. The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences, 77(10), 1852-1863. https://doi.org/10.1093/geronb/gbac090

Objectives: Understanding whether and how caregivers' capability to "live well"changes over time, and the factors associated with change, could help target effective caregiver support. Methods: We analyzed 3 time points (12 months apart) of Improving... Read More about "Living Well" Trajectories Among Family Caregivers of People With Mild-to-Moderate Dementia in the IDEAL Cohort.

Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts (2022)
Journal Article
Nelson, P. T., Brayne, C., Flanagan, M. E., Abner, E. L., Agrawal, S., Attems, J., …Schneider, J. A. (2022). Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts. Acta Neuropathologica, 144(1), 27-44. https://doi.org/10.1007/s00401-022-02444-1

Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) and Alzheimer’s disease neuropathologic change (ADNC) are each associated with substantial cognitive impairment in aging populations. However, the prevalence of LAT... Read More about Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts.

Characteristics of people living with undiagnosed dementia: findings from the CFAS Wales study (2022)
Journal Article
Gamble, L. D., Matthews, F. E., Jones, I. R., Hillman, A. E., Woods, B., Macleod, C. A., …Clare, L. (2022). Characteristics of people living with undiagnosed dementia: findings from the CFAS Wales study. BMC Geriatrics, 22(1), Article 409. https://doi.org/10.1186/s12877-022-03086-4

Background: Many people living with dementia remain undiagnosed, with diagnosis usually occurring long after signs and symptoms are present. A timely diagnosis is important for the wellbeing of the person living with dementia and the family, allowing... Read More about Characteristics of people living with undiagnosed dementia: findings from the CFAS Wales study.

Predictors of Awareness of Functional Ability in People with Dementia: The Contribution of Personality, Cognition, and Neuropsychiatric Symptoms - Findings from the IDEAL Program (2022)
Journal Article
Martyr, A., Gamble, L. D., Nelis, S. M., Collins, R., Alexander, C. M., Morris, R. G., …Clare, L. (2022). Predictors of Awareness of Functional Ability in People with Dementia: The Contribution of Personality, Cognition, and Neuropsychiatric Symptoms - Findings from the IDEAL Program. Dementia and Geriatric Cognitive Disorders, 51(3), 221-232. https://doi.org/10.1159/000524607

Introduction: Discrepancy scores reflecting the difference between parallel ratings made by people living with dementia (PwD) in the mild-to-moderate stages and by their informants provide a way to investigate awareness of functional ability in relat... Read More about Predictors of Awareness of Functional Ability in People with Dementia: The Contribution of Personality, Cognition, and Neuropsychiatric Symptoms - Findings from the IDEAL Program.

The availability of local primary care services, satisfaction with health services and self-rated health in older English adults: A population-based study (2022)
Journal Article
Wu, Y. T., Prina, M., & Matthews, F. (2022). The availability of local primary care services, satisfaction with health services and self-rated health in older English adults: A population-based study. Preventive Medicine Reports, 27, Article 101786. https://doi.org/10.1016/j.pmedr.2022.101786

Primary care services can play an important role in addressing health inequalities and challenges of population ageing. The aim of this study is to investigate whether the availability of local primary care services can support satisfaction with heal... Read More about The availability of local primary care services, satisfaction with health services and self-rated health in older English adults: A population-based study.

Measuring older people’s socioeconomic position: a scoping review of studies of self-rated health, health service and social care use (2022)
Journal Article
Spiers, G. F., Liddle, J. E., Stow, D., Searle, B., Whitehead, I. O., Kingston, A., …Hanratty, B. (2022). Measuring older people’s socioeconomic position: a scoping review of studies of self-rated health, health service and social care use. Journal of Epidemiology and Community Health, 76(6), 572-579. https://doi.org/10.1136/jech-2021-218265

Background The challenges of measuring socioeconomic position in older populations were first set out two decades ago. However, the question of how best to measure older people’s socioeconomic position remains pertinent as populations age and health... Read More about Measuring older people’s socioeconomic position: a scoping review of studies of self-rated health, health service and social care use.

Minimal Impact of COVID-19 Pandemic on the Mental Health and Wellbeing of People Living With Dementia: Analysis of Matched Longitudinal Data From the IDEAL Study (2022)
Journal Article
Sabatini, S., Bennett, H. Q., Martyr, A., Collins, R., Gamble, L. D., Matthews, F. E., …Clare, L. (2022). Minimal Impact of COVID-19 Pandemic on the Mental Health and Wellbeing of People Living With Dementia: Analysis of Matched Longitudinal Data From the IDEAL Study. Frontiers in Psychiatry, 13, Article 849808. https://doi.org/10.3389/fpsyt.2022.849808

Objective: Research suggests a decline in the mental health and wellbeing of people with dementia (PwD) during the COVID-19 pandemic; however few studies have compared data collected pre-pandemic and during the pandemic. Moreover, none have compared... Read More about Minimal Impact of COVID-19 Pandemic on the Mental Health and Wellbeing of People Living With Dementia: Analysis of Matched Longitudinal Data From the IDEAL Study.

A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies (2022)
Journal Article
Bennett, H. Q., Kingston, A., Lourida, I., Robinson, L., Corner, L., Brayne, C., …Jagger, C. (2022). A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies. PLoS Medicine, 19(3), Article e1003936. https://doi.org/10.1371/journal.pmed.1003936

Background Previous research has examined the improvements in healthy years if different health conditions are eliminated, but often with cross-sectional data, or for a limited number of conditions. We used longitudinal data to estimate disability-fr... Read More about A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies.

Longitudinal Trajectories of Quality of Life among People with Mild-To-Moderate Dementia: A Latent Growth Model Approach with IDEAL Cohort Study Data (2022)
Journal Article
Clare, L., Gamble, L. D., Martyr, A., Sabatini, S., Nelis, S. M., Quinn, C., …Matthews, F. E. (2022). Longitudinal Trajectories of Quality of Life among People with Mild-To-Moderate Dementia: A Latent Growth Model Approach with IDEAL Cohort Study Data. The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences, 77(6), 1037-1050. https://doi.org/10.1093/geronb/gbac022

Objectives: We aimed to examine change over time in self-rated quality of life (QoL) in people with mild-To-moderate dementia and identify subgroups with distinct QoL trajectories. Methods: We used data from people with mild-To-moderate dementia foll... Read More about Longitudinal Trajectories of Quality of Life among People with Mild-To-Moderate Dementia: A Latent Growth Model Approach with IDEAL Cohort Study Data.

A Comparison of Well-Being of Carers of People with Dementia and Their Ability to Manage Before and During the COVID-19 Pandemic: Findings from the IDEAL Study (2022)
Journal Article
Gamble, L. D., Parker, S., Quinn, C., Bennett, H. Q., Martyr, A., Sabatini, S., Pentecost, C., Collins, R., Dawson, E., Hunt, A., Allan, L., Burns, A., Litherland, R., Victor, C., Matthews, F. E., & Clare, L. (2022). A Comparison of Well-Being of Carers of People with Dementia and Their Ability to Manage Before and During the COVID-19 Pandemic: Findings from the IDEAL Study. Journal of Alzheimer's Disease, 88(2), 679-692. https://doi.org/10.3233/JAD-220221

Background: Social restriction measures imposed to curb the spread of COVID-19 in the United Kingdom impacted on carers of people with dementia, limiting access to support services and increasing perceived burden of caring. Few studies have compared... Read More about A Comparison of Well-Being of Carers of People with Dementia and Their Ability to Manage Before and During the COVID-19 Pandemic: Findings from the IDEAL Study.

The Use and Costs of Paid and Unpaid Care for People with Dementia: Longitudinal Findings from the IDEAL Cohort (2022)
Journal Article
Henderson, C., Knapp, M., Martyr, A., Gamble, L. D., Nelis, S. M., Quinn, C., …Clare, L. (2022). The Use and Costs of Paid and Unpaid Care for People with Dementia: Longitudinal Findings from the IDEAL Cohort. Journal of Alzheimer's Disease, 86(1), 135-153. https://doi.org/10.3233/JAD-215117

Background: The drivers of costs of care for people with dementia are not well understood and little is known on the costs of care for those with rarer dementias. Objective: To characterize use and costs of paid and unpaid care over time in a cohort... Read More about The Use and Costs of Paid and Unpaid Care for People with Dementia: Longitudinal Findings from the IDEAL Cohort.

Impact of COVID-19 on 'Living Well' with Mild-to-Moderate Dementia in the Community: Findings from the IDEAL Cohort (2022)
Journal Article
Clare, L., Martyr, A., Gamble, L. D., Pentecost, C., Collins, R., Dawson, E., …Victor, C. (2022). Impact of COVID-19 on 'Living Well' with Mild-to-Moderate Dementia in the Community: Findings from the IDEAL Cohort. Journal of Alzheimer's Disease, 85(2), 921-936. https://doi.org/10.3233/JAD-215095

Background: Negative impacts of the COVID-19 pandemic on people with dementia have been widely-documented, but most studies have relied on carer reports and few have compared responses to information collected before the pandemic. Objective: We aimed... Read More about Impact of COVID-19 on 'Living Well' with Mild-to-Moderate Dementia in the Community: Findings from the IDEAL Cohort.