All Outputs (139)

International variation in dialysis discontinuation in patients with advanced kidney disease (2020)
Journal Article
Jassal, S. V., Larkina, M., Jager, K. J., Murtagh, F. E., O’Hare, A. M., Hanafusa, N., Morgenstern, H., Port, F. K., McCullough, K., Pisoni, R., Tentori, F., Perlman, R., & Swartz, R. D. (2020). International variation in dialysis discontinuation in patients with advanced kidney disease. Canadian Medical Association Journal, 192(35), E995-E1002. https://doi.org/10.1503/cmaj.191631

BACKGROUND: Decisions about dialysis for advanced kidney disease are often strongly shaped by sociocultural and system-level factors rather than the priorities and values of individual patients. We examined international variation in the uptake of co... Read More about International variation in dialysis discontinuation in patients with advanced kidney disease.

Health of mothers of children with a life-limiting condition: a protocol for comparative cohort study using the Clinical Practice Research Datalink (2020)
Journal Article
Fraser, L. K., Murtagh, F. E., Sheldon, T., Gilbody, S., & Hewitt, C. (2020). Health of mothers of children with a life-limiting condition: a protocol for comparative cohort study using the Clinical Practice Research Datalink. BMJ open, 10(7), Article e034024. https://doi.org/10.1136/bmjopen-2019-034024

INTRODUCTION: There are now nearly 50 000 children with a life-limiting or life-threatening condition in the UK. These include conditions where there is no reasonable hope of cure and from which they will die, as well as conditions for which curative... Read More about Health of mothers of children with a life-limiting condition: a protocol for comparative cohort study using the Clinical Practice Research Datalink.

The development and cognitive testing of the positive outcomes HIV PROM: A brief novel patient-reported outcome measure for adults living with HIV (2020)
Journal Article
Bristowe, K., Murtagh, F. E., Clift, P., James, R., Josh, J., Platt, M., Whetham, J., Nixon, E., Post, F. A., McQuillan, K., Cheallaigh, C. N., Kall, M., Anderson, J., Sullivan, A. K., & Harding, R. (2020). The development and cognitive testing of the positive outcomes HIV PROM: A brief novel patient-reported outcome measure for adults living with HIV. Health and quality of life outcomes, 18(1), Article 214. https://doi.org/10.1186/s12955-020-01462-5

© 2020 The Author(s). Background: People living with HIV experience burdensome multidimensional symptoms and concerns requiring person-centred care. Routine use of patient reported outcome measures can improve outcomes. There is no brief patient repo... Read More about The development and cognitive testing of the positive outcomes HIV PROM: A brief novel patient-reported outcome measure for adults living with HIV.

Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study (2020)
Journal Article
Baddeley, E., Bravington, A., Johnson, M., Currow, D., Murtagh, F. E., Boland, E., Obita, G., Nelson, A., Seddon, K., Oliver, A., Noble, S., & Boland, J. (2020). Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study. BMJ open, 10(6), Article 039154. https://doi.org/10.1136/bmjopen-2020-039154

INTRODUCTION: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.

Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care (2020)
Journal Article
ElMokhallalati, Y., Bradley, S. H., Chapman, E., Ziegler, L., Murtagh, F. E., Johnson, M. J., & Bennett, M. I. (2020). Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care. Palliative medicine, 34(8), 989-1005. https://doi.org/10.1177/0269216320929552

Background Despite increasing evidence of the benefits of early access to palliative care, many patients do not receive palliative care in a timely manner. A systematic approach in primary care can facilitate earlier identification of patients with... Read More about Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care.

Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care (2020)
Journal Article
Shah, K. K., Murtagh, F. E., McGeechan, K., Crail, S. M., Burns, A., & Morton, R. L. (2020). Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care. BMC Nephrology, 21(1), 160. https://doi.org/10.1186/s12882-020-01830-9

BACKGROUND: To measure health-related and care-related quality of life among informal caregivers of older people with end-stage kidney disease (ESKD), and to determine the association between caregiver quality of life and care recipient's treatment t... Read More about Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care.

Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach (2020)
Journal Article
Yorganci, E., Evans, C. J., Johnson, H., Barclay, S., Murtagh, F. E., Yi, D., Gao, W., Pickles, A., & Koffman, J. (2020). Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach. Palliative medicine, https://doi.org/10.1177/0269216320905064

Background Evaluations of complex interventions compared to usual care provided in palliative care are increasing. Not describing usual care may affect the interpretation of an intervention’s effectiveness, yet how it can be described remains unclear... Read More about Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach.

Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study (2020)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E., Downing, J., Powell, R. A., Abas, M., Lohfeld, L., Ali, Z., Atieno, M., Haufiku, D., Guma, S., Luyirika, E. B., Mwangi-Powell, F. N., Higginson, I. J., & Harding, R. (2020). Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study. Palliative medicine, 34(3), 319-335. https://doi.org/10.1177/0269216319900137

© The Author(s) 2020. Background: Paediatric life-limiting and life-threatening conditions (life-limiting conditions) place significant strain on children, families and health systems. Given high service use among this population, it is essential tha... Read More about Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study.

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries (2020)
Journal Article
Van Biesen, W., Jha, V., Abu-Alfa, A. K., Andreoli, S. P., Ashuntantang, G., Bernieh, B., …Garcia Garcia, G. (2020). Considerations on equity in management of end-stage kidney disease in low- and middle-income countries. Kidney International Supplements, 10(1), e63-e71. https://doi.org/10.1016/j.kisu.2019.11.004

Achievement of equity in health requires development of a health system in which everyone has a fair opportunity to attain their full health potential. The current, large country-level variation in the reported incidence and prevalence of treated end... Read More about Considerations on equity in management of end-stage kidney disease in low- and middle-income countries.

Supportive care for end-stage kidney disease: an integral part of kidney services across a range of income settings around the world (2020)
Journal Article
Hole, B., Hemmelgarn, B., Brown, E., Brown, M., McCulloch, M. I., Zuniga, C., Andreoli, S. P., Blake, P. G., Couchoud, C., Cueto-Manzano, A. M., Dreyer, G., Garcia Garcia, G., Jager, K. J., McKnight, M., Morton, R. L., Murtagh, F. E., Naicker, S., Obrador, G. T., Perl, J., Rahman, M., …Caskey, F. J. (2020). Supportive care for end-stage kidney disease: an integral part of kidney services across a range of income settings around the world. Kidney International Supplements, 10(1), e86-e94. https://doi.org/10.1016/j.kisu.2019.11.008

© 2020 International Society of Nephrology A key component of treatment for all people with advanced kidney disease is supportive care, which aims to improve quality of life and can be provided alongside therapies intended to prolong life, such as di... Read More about Supportive care for end-stage kidney disease: an integral part of kidney services across a range of income settings around the world.

Towards person-centered quality care for children with life-limiting and life-threatening illness: self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study (2019)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E. M., Downing, J., Powell, R. A., Abas, M., Ali, L. L. Z., Atieno, M., Haufiku, D., Guma, S., Luyirika, E. B. K., Mwangi-Powell, F. N., Higginson, I. J., Harding, R., & Murtagh, F. (in press). Towards person-centered quality care for children with life-limiting and life-threatening illness: self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study. Palliative medicine,

Abstract Background: Paediatric life-limiting and life-threatening conditionslife-limiting conditions place significant strain on children, families and health systems. Given high service use among this population, it is essential that care address... Read More about Towards person-centered quality care for children with life-limiting and life-threatening illness: self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study.

The effects of opioids on cognition in older adults with cancer and chronic non-cancer pain: A systematic review (2019)
Journal Article
Pask, S., Dell’Olio, M., Murtagh, F. E., & Boland, J. W. (2020). The effects of opioids on cognition in older adults with cancer and chronic non-cancer pain: A systematic review. Journal of pain and symptom management, 59(4), 871-893. https://doi.org/10.1016/j.jpainsymman.2019.10.022

Context Opioids are prescribed to manage moderate to severe pain and can be used with older adults; however, they may lead to several adverse effects, including cognitive impairment. Objective To identify, appraise and synthesise evidence on i)... Read More about The effects of opioids on cognition in older adults with cancer and chronic non-cancer pain: A systematic review.

What are the main symptoms and concerns reported by patients with advanced chronic heart failure?—a secondary analysis of the Palliative care Outcome Scale (POS) and Integrated Palliative care Outcome Scale (IPOS) (2019)
Journal Article
Oriani, A., Guo, P., Gadoud, A., Dunleavy, L., Kane, P., & Murtagh, F. E. (2019). What are the main symptoms and concerns reported by patients with advanced chronic heart failure?—a secondary analysis of the Palliative care Outcome Scale (POS) and Integrated Palliative care Outcome Scale (IPOS). Annals of palliative medicine, 8(5), 775-780. https://doi.org/10.21037/apm.2019.08.10

© Annals of Palliative Medicine. All rights reserved. There is a lack of valid disease-specific patient-reported outcome measures (PROMs) for detecting symptoms and concerns in patients with advanced chronic heart failure (CHF). The Palliative care O... Read More about What are the main symptoms and concerns reported by patients with advanced chronic heart failure?—a secondary analysis of the Palliative care Outcome Scale (POS) and Integrated Palliative care Outcome Scale (IPOS).

Managing uncertain recovery for patients nearing the end of life in hospital: a mixed-methods feasibility cluster randomised controlled trial of the AMBER care bundle (2019)
Journal Article
Koffman, J., Yorganci, E., Yi, D., Gao, W., Murtagh, F., Pickles, A., Barclay, S., Johnson, H., Wilson, R., Sampson, L., Droney, J., Farquhar, M., Prevost, T., & Evans, C. J. (2019). Managing uncertain recovery for patients nearing the end of life in hospital: a mixed-methods feasibility cluster randomised controlled trial of the AMBER care bundle. Trials, 20(1), Article 506. https://doi.org/10.1186/s13063-019-3612-0

Background The AMBER (Assessment, Management, Best Practice, Engagement, Recovery Uncertain) care bundle is a complex intervention used in UK hospitals to support patients with uncertain recovery. However, it has yet to be evaluated in a randomised... Read More about Managing uncertain recovery for patients nearing the end of life in hospital: a mixed-methods feasibility cluster randomised controlled trial of the AMBER care bundle.

Establishing key criteria to define and compare models of specialist palliative care: a mixed-methods study using qualitative interviews and Delphi survey (2019)
Journal Article
Firth, A. M., O’Brien, S. M., Guo, P., Seymour, J., Richardson, H., Bridges, C., Hocaoglu, M. B., Grande, G., Dzingina, M., Higginson, I. J., & Murtagh, F. E. (2019). Establishing key criteria to define and compare models of specialist palliative care: a mixed-methods study using qualitative interviews and Delphi survey. Palliative medicine, https://doi.org/10.1177/0269216319858237

Background: Specialist palliative care services have various configurations of staff, processes and interventions, which determine how care is delivered. Currently, there is no consistent way to define and distinguish these different models of care.... Read More about Establishing key criteria to define and compare models of specialist palliative care: a mixed-methods study using qualitative interviews and Delphi survey.

A brief, patient- and proxy-reported outcome measure in advanced illness: Validity, reliability and responsiveness of the Integrated Palliative care Outcome Scale (IPOS) (2019)
Journal Article
Murtagh, F. E., Ramsenthaler, C., Firth, A., Groeneveld, E. I., Lovell, N., Simon, S. T., Denzel, J., Guo, P., Bernhardt, F., Schildmann, E., van Oorschot, B., Hodiamont, F., Streitwieser, S., Higginson, I. J., & Bausewein, C. (in press). A brief, patient- and proxy-reported outcome measure in advanced illness: Validity, reliability and responsiveness of the Integrated Palliative care Outcome Scale (IPOS). Palliative medicine, 026921631985426. https://doi.org/10.1177/0269216319854264

Background: Few measures capture the complex symptoms and concerns of those receiving palliative care. Aim: To validate the Integrated Palliative care Outcome Scale, a measure underpinned by extensive psychometric development, by evaluating its vali... Read More about A brief, patient- and proxy-reported outcome measure in advanced illness: Validity, reliability and responsiveness of the Integrated Palliative care Outcome Scale (IPOS).

Which outcome domains are important in palliative care and when? An international expert consensus workshop, using the nominal group technique (2019)
Journal Article
de Wolf-Linder, S., Dawkins, M., Wicks, F., Pask, S., Eagar, K., Evans, C. J., Higginson, I. J., & Murtagh, F. E. (in press). Which outcome domains are important in palliative care and when? An international expert consensus workshop, using the nominal group technique. Palliative medicine, 026921631985415. https://doi.org/10.1177/0269216319854154

© The Author(s) 2019. Background: When capturing patient-level outcomes in palliative care, it is essential to identify which outcome domains are most important and focus efforts to capture these, in order to improve quality of care and minimise coll... Read More about Which outcome domains are important in palliative care and when? An international expert consensus workshop, using the nominal group technique.

Towards person‐centred care for people living with HIV: what core outcomes matter, and how might we assess them? A cross‐national multi‐centre qualitative study with key stakeholders (2019)
Journal Article
Bristowe, K., Clift, P., James, R., Josh, J., Platt, M., Whetham, J., Nixon, E., Post, F. A., McQuillan, K., Ní Cheallaigh, C., Murtagh, F. E., Anderson, J., Sullivan, A. K., & Harding, R. (2019). Towards person‐centred care for people living with HIV: what core outcomes matter, and how might we assess them? A cross‐national multi‐centre qualitative study with key stakeholders. HIV Medicine, 20(8), 542-554. https://doi.org/10.1111/hiv.12758

Objectives People living with HIV (PLWH) have multidimensional concerns requiring person‐centred care. Routine use of patient‐reported outcome measures (PROMs) improves outcomes. No brief PROM currently reflects the breadth of concerns for PLWH. This... Read More about Towards person‐centred care for people living with HIV: what core outcomes matter, and how might we assess them? A cross‐national multi‐centre qualitative study with key stakeholders.

Health-related quality of life and well-being in people over 75 years of age with end-stage kidney disease managed with dialysis or comprehensive conservative care: A cross-sectional study in the UK and Australia (2019)
Journal Article
Shah, K. K., Murtagh, F. E., McGeechan, K., Crail, S., Burns, A., Tran, A. D., & Morton, R. L. (2019). Health-related quality of life and well-being in people over 75 years of age with end-stage kidney disease managed with dialysis or comprehensive conservative care: A cross-sectional study in the UK and Australia. BMJ open, 9(5), Article e027776. https://doi.org/10.1136/bmjopen-2018-027776

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objective To measure health-related quality of life (HRQoL) and well-being in older people with end-stage ki... Read More about Health-related quality of life and well-being in people over 75 years of age with end-stage kidney disease managed with dialysis or comprehensive conservative care: A cross-sectional study in the UK and Australia.

A longitudinal cohort study of symptoms and other concerns among Nigerian people with stages 3–5 chronic kidney diseases: study protocol (2019)
Journal Article
Olagunju, A. T., Fadipe, B., Buraimoh, R. W., Ale, O. K., Umeizudike, T. I., Ogbolu, R. E., Buyinza, N., Bayuo, J., Mutedzi, B., Nkhoma, K., Namisango, E., Bristowe, K., Yi, D., Downing, J., Aina, O. F., Adeyemi, J. D., Murtagh, F. E., & Harding, R. (2019). A longitudinal cohort study of symptoms and other concerns among Nigerian people with stages 3–5 chronic kidney diseases: study protocol. Annals of palliative medicine, 8(2), 190-198. https://doi.org/10.21037/apm.2018.10.03

Background: The burden of symptoms and other concerns in chronic kidney disease (CKD) is known to be high, adversely affecting the quality of life of the growing number of those with this condition in developing countries. In this paper, we describe... Read More about A longitudinal cohort study of symptoms and other concerns among Nigerian people with stages 3–5 chronic kidney diseases: study protocol.