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Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials (2011)
Journal Article
Shahin, Y., Khan, J. A., Samuel, N., & Chetter, I. (2011). Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials. Atherosclerosis, 216(1), 7-16. https://doi.org/10.1016/j.atherosclerosis.2011.02.044

ObjectiveSeveral studies have assessed the effect of angiotensin converting enzyme inhibitors (ACEIs) on endothelial dysfunction as measured by brachial flow-mediated vasodilatation (FMD). We conducted a meta-analysis to investigate this effect in co... Read More about Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials.

Randomized clinical trial of endovenous laser ablation compared with conventional surgery for great saphenous varicose veins (2011)
Journal Article
Carradice, D., Mekako, A. I., Mazari, F. A. K., Samuel, N., Hatfield, J., & Chetter, I. C. (2011). Randomized clinical trial of endovenous laser ablation compared with conventional surgery for great saphenous varicose veins. British journal of surgery, 98(4), 501-510. https://doi.org/10.1002/bjs.7394

Background: Endovenous laser ablation (EVLA) is a popular minimally invasive treatment for varicose veins. Surgical treatment, featuring junctional ligation and inversion stripping, has shown excellent clinical and cost effectiveness. The clinical ef... Read More about Randomized clinical trial of endovenous laser ablation compared with conventional surgery for great saphenous varicose veins.

Ultrasound evaluation of carotid body tumours (2011)
Journal Article
Samuel, N., Smith, G., Wolstenhulme, S., & Chetter, I. (2011). Ultrasound evaluation of carotid body tumours. Ultrasound, 19(1), 26-30. https://doi.org/10.1258/ult.2010.010037

Carotid body tumour (CBT) is a rare neoplasm that usually presents as an asymptomatic slow-growing neck mass at the carotid bifurcation. Due to these benign attributes, CBTs often go undiagnosed for a few years before a lateral neck mass becomes clin... Read More about Ultrasound evaluation of carotid body tumours.

Do angiotensin converting enzyme inhibitors improve walking distance in patients with symptomatic lower limb arterial disease? A systematic review and meta-analysis of randomised controlled trials (2010)
Journal Article
Shahin, Y., Mazari, F., & Chetter, I. (2011). Do angiotensin converting enzyme inhibitors improve walking distance in patients with symptomatic lower limb arterial disease? A systematic review and meta-analysis of randomised controlled trials. International journal of surgery, 9(3), 209-213. https://doi.org/10.1016/j.ijsu.2010.12.006

Background
Several studies have reported the clinical effects of long-term treatment with cardioprotective medications in patients with lower limb peripheral arterial disease (PAD) in terms of reducing cardiovascular morbidity and mortality. A numbe... Read More about Do angiotensin converting enzyme inhibitors improve walking distance in patients with symptomatic lower limb arterial disease? A systematic review and meta-analysis of randomised controlled trials.

Recognition of inflammatory aneurysms in abdominal aortic aneurysm screening and surveillance (2010)
Journal Article
Smith, G. E., Samuel, N., Wolstenholme, S., Akomolafe, A. B., & Chetter, I. C. (2010). Recognition of inflammatory aneurysms in abdominal aortic aneurysm screening and surveillance. Ultrasound, 18(4), 186-190. https://doi.org/10.1258/ult.2010.010035

Inflammatory abdominal aortic aneurysms (IAAAs) account for 3-10% of all abdominal aortic aneurysms and are characterized by a thickened aneurysmal wall, with extensive fibrosis and adhesions. Ultrasound remains the investigation of choice for diagno... Read More about Recognition of inflammatory aneurysms in abdominal aortic aneurysm screening and surveillance.

Statins and ischaemia reperfusion injury: a molecular biological review (2010)
Journal Article
N.A. Abdul Rahman, M., & C. Chetter, I. (2010). Statins and ischaemia reperfusion injury: a molecular biological review. Current Vascular Pharmacology, 8(6), 831-835. https://doi.org/10.2174/157016110793563780

The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its choleste... Read More about Statins and ischaemia reperfusion injury: a molecular biological review.

A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal ao (2010)
Journal Article
Rahman, M. A., Khan, J. A., Mazari, F. A. K., Mockford, K., McCollum, P. T., & Chetter, I. (2011). A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal ao. Annals of vascular surgery, 25(1), 32-38. https://doi.org/10.1016/j.avsg.2010.06.006

BackgroundA double-blind, randomized controlled trial was carried out to study the effects of statins on matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in areas of peak and low abdominal aortic aneurysm (A... Read More about A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal ao.

Computerized dynamic posturography in the objective assessment of balance in patients with intermittent claudication (2010)
Journal Article
Mockford, K. A., Mazari, F. A. K., Jordan, A. R., Vanicek, N., Chetter, I. C., & Coughlin, P. A. (2011). Computerized dynamic posturography in the objective assessment of balance in patients with intermittent claudication. Annals of vascular surgery, 25(2), 182-190. https://doi.org/10.1016/j.avsg.2010.07.021

One-third of all elderly patients fall each year and impaired balance has been recognized as a specific risk factor. Intermittent claudication is common among the elderly population, affecting approximately 5% of the population over the age of 50. Th... Read More about Computerized dynamic posturography in the objective assessment of balance in patients with intermittent claudication.

Hull early walking aid for rehabilitation of transtibial amputees - randomized controlled trial (HEART) (2010)
Journal Article
Mazari, F. A. K., Mockford, K., Vanicek, N., Barnett, C., Khan, J. A., Brown, B., Smith, L., Polman, R. C., Hancock, A., & Chetter, I. C. (2010). Hull early walking aid for rehabilitation of transtibial amputees - randomized controlled trial (HEART). Journal of vascular surgery, 52(6), 1564-1571. https://doi.org/10.1016/j.jvs.2010.07.006

Purpose: To compare articulated and nonarticulated early walking aids (EWAs) for clinical and quality-of-life outcomes in transtibial amputees. Methods: Patients undergoing lower limb amputation in a tertiary-care vascular surgical unit were screened... Read More about Hull early walking aid for rehabilitation of transtibial amputees - randomized controlled trial (HEART).

Randomized clinical trial of tranexamic acid-free fibrin sealant during vascular surgical procedures (2010)
Journal Article
Chalmers, R. T. A., Darling, R. C., Wingard, J. T., Chetter, I., Cutler, B., Kern, J. A., & Hart, J. C. (2010). Randomized clinical trial of tranexamic acid-free fibrin sealant during vascular surgical procedures. British journal of surgery, 97(12), 1784-1789. https://doi.org/10.1002/bjs.7235

Background: This study evaluated the safety and haemostatic effectiveness of a fibrin sealant (EVICELTM Fibrin Sealant (Human)) during vascular surgery. Methods: This prospective randomized controlled trial compared the haemostatic effectiveness of f... Read More about Randomized clinical trial of tranexamic acid-free fibrin sealant during vascular surgical procedures.

Kinematic adaptations to ischemic pain in claudicants during continuous walking (2010)
Journal Article
Mockford, K. A., Vanicek, N., Jordan, A., Chetter, I. C., & Coughlin, P. A. (2010). Kinematic adaptations to ischemic pain in claudicants during continuous walking. Gait and Posture, 32(3), 395-399. https://doi.org/10.1016/j.gaitpost.2010.06.021

Intermittent claudication has been associated with impaired gait and balance. The study aim was to compare gait adaptations over time between claudicants classified with good versus poor balance. Kinematic data were collected from 24 claudicants duri... Read More about Kinematic adaptations to ischemic pain in claudicants during continuous walking.

Prospective observational study for comparison of use of Short Form-36 dimension scores and patient responses for derivation of preference based Short Form-6D index to calculate of quality adjusted life years (QALYs) for economic analyses in patients with (2010)
Presentation / Conference Contribution
Mazari, F., Abdul Rahman, H., Khan, J., Mockford, K., McCollum, P., & Chetter, I. Prospective observational study for comparison of use of Short Form-36 dimension scores and patient responses for derivation of preference based Short Form-6D index to calculate of quality adjusted life years (QALYs) for economic analyses in patients with

Energy delivery during 810 nm endovenous laser ablation of varicose veins and post-procedural morbidity (2010)
Journal Article
Carradice, D., Mazari, F. A., Mekako, A., Hatfield, J., Allgar, V., & Chetter, I. (2010). Energy delivery during 810 nm endovenous laser ablation of varicose veins and post-procedural morbidity. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 40(3), 393-398. https://doi.org/10.1016/j.ejvs.2010.04.010

Aim: The durability of occlusion post endovenous laser therapy (EVLT) for varicose veins is linked to the magnitude of energy delivered to the vein and consequently increasing amounts of energy are employed. The aim of this study is to establish whet... Read More about Energy delivery during 810 nm endovenous laser ablation of varicose veins and post-procedural morbidity.

Cost utility analysis of a randomised control trial of percutaneous transluminal angioplasty (PTA), supervised exercise programme (SEP) and combined treatment (PTA plus SEP) for patients with intermittent claudication (IC) due to femoropopliteal disease (2010)
Presentation / Conference Contribution
Mazari, F., Abdul Rahman, H., Khan, J., McCollum, P., Gulati, S., Mehta, T., & Chetter, I. Cost utility analysis of a randomised control trial of percutaneous transluminal angioplasty (PTA), supervised exercise programme (SEP) and combined treatment (PTA plus SEP) for patients with intermittent claudication (IC) due to femoropopliteal disease

Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery (2009)
Journal Article
Mekako, A. I., Chetter, I. C., Coughlin, P. A., Hatfield, J., & McCollum, P. T. (2010). Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery. British journal of surgery, 97(1), 29-36. https://doi.org/10.1002/bjs.6849

Background: Wound infection rates of up to 16 per cent are reported following varicose vein surgery and the value of antibiotic prophylaxis in clean surgery remains unclear. Methods: Some 443 patients undergoing varicose vein surgery randomly receive... Read More about Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery.