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Hidden morbidity: the results of a collaborative community Chronic Obstructive Pulmonary Disease screening initiative (2018)
Journal Article
Crooks, M. G., Thompson, J. L., Cummings, H., Watkins, K., Jackson, N., Platten, S., …Faruqi, S. (2019). Hidden morbidity: the results of a collaborative community Chronic Obstructive Pulmonary Disease screening initiative. Clinical Respiratory Journal, 13(1), 43-49. doi:10.1111/crj.12978

Chronic obstructive pulmonary disease (COPD) often goes unrecognised resulting in people living with the disease without a diagnosis. Screening of asymptomatic individuals is not recommended but case‐finding is encouraged to detect early disease. We... Read More

Agreement between blood draw techniques for assessing platelet activation by flow cytometry (2018)
Journal Article
Welch, E. L., Crooks, M. G., & Hart, S. P. (in press). Agreement between blood draw techniques for assessing platelet activation by flow cytometry. Platelets, 1-5. doi:10.1080/09537104.2018.1535705

It is widely believed that assays of platelet activation are susceptible to preanalytical variables related to blood draw technique. We assessed platelet activation by whole blood flow cytometry and investigated the effects of: (1) drawing blood into... Read More

Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation (2017)
Journal Article
Crooks, M. G., Williamson, J. D., Wright, C. E., Morice, A. H., Crooks, M., Morice, A., …Williamson, J. (2017). Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation. Lung, 195(3), (289-294). doi:10.1007/s00408-017-9996-2. ISSN 0341-2040

Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases during acute exacerbations (AE-COPD), representing a possible metric of clinical deteriorat... Read More

Coagulation and anticoagulation in idiopathic pulmonary fibrosis (2015)
Journal Article
Crooks, M. G., & Hart, S. P. (2015). Coagulation and anticoagulation in idiopathic pulmonary fibrosis. European Respiratory Review, 24(137), (392-399). doi:10.1183/16000617.00008414. ISSN 0905-9180

Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events. Coagulat... Read More

Objective measurement of cough frequency during COPD exacerbation convalescence (2015)
Journal Article
Crooks, M. G., Hayman, Y., Innes, A., Williamson, J., Wright, C. E., & Morice, A. H. (2016). Objective measurement of cough frequency during COPD exacerbation convalescence. Lung, 194(1), (117-120). doi:10.1007/s00408-015-9782-y. ISSN 0341-2040

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Cough and sputum production are associated with adverse outcomes in COPD and are common during COPD exacerbation (AE-COPD). This study of objective co... Read More

Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor (2014)
Journal Article
Crooks, M. G., Naseem, K. M., Morice, A. H., Hart, S. P., Crooks, M., Hart, S., …Fahim, A. (2014). Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor. PloS one, 9(10), (e111347). doi:10.1371/journal.pone.0111347. ISSN 1932-6203

Introduction Idiopathic Pulmonary Fibrosis (IPF) is a progressive, incurable fibrotic interstitial lung disease with a prognosis worse than many cancers. Its pathogenesis is poorly understood. Activated platelets can release pro-fibrotic mediators th... Read More

Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis. (2014)
Journal Article
Crooks, M. G., Morice, A. H., Hart, S. P., Crooks, M., Hart, S., Morice, A., & Fahim, A. (2014). Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis. Lung, 192(2), (277-284). doi:10.1007/s00408-013-9546-5. ISSN 0341-2040

Purpose Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia and its prognosis is poor. Epidemiological evidence suggests an association of IPF with vascular disease and thrombotic tendency, which may be related to... Read More

Idiopathic Pulmonary Fibrosis is Associated with Circulating Antiepithelial Antibodies (2012)
Journal Article
Fahim, A., Chong, M. C., Crooks, M. G., & Hart, S. P. (2012). Idiopathic Pulmonary Fibrosis is Associated with Circulating Antiepithelial Antibodies. Lung, 190(4), 451-458. doi:10.1007/s00408-012-9390-z

PurposeIdiopathic pulmonary fibrosis (IPF) is a restrictive fibrotic lung disease of uncertain etiology. Alveolar epithelial injury may be one of the inciting triggers in the pathogenesis of this disorder. We hypothesized that circulating antibodies... Read More