All Outputs (85)

Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial (2024)
Journal Article
Kendrick, T., Stuart, B., Bowers, H., Haji Sadeghi, M., Page, H., Dowrick, C., Moore, M., Gabbay, M., Leydon, G. M., Yao, G. L., Little, P., Griffiths, G., Lewis, G., May, C., Moncrieff, J., Johnson, C. F., Macleod, U., Gilbody, S., Dewar-Haggart, R., Williams, S., …Geraghty, A. W. (2024). Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial. Jama Network Open, 7(6), Article e2418383. https://doi.org/10.1001/jamanetworkopen.2024.18383

Importance: There is significant concern regarding increasing long-term antidepressant treatment for depression beyond an evidence-based duration. Objective: To determine whether adding internet and telephone support to a family practitioner review t... Read More about Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial.

Challenges and opportunities for cervical screening in women over the age of 50 years: a qualitative study (2022)
Journal Article
Bravington, A., Chen, H., Dyson, J., Jones, L., Dalgliesh, C., Bryan, A., Patnick, J., & Macleod, U. (2022). Challenges and opportunities for cervical screening in women over the age of 50 years: a qualitative study. The British journal of general practice : the journal of the Royal College of General Practitioners, 72(725), e873-e881. https://doi.org/10.3399/BJGP.2022.0036

BACKGROUND: Cervical cancer is a preventable disease. Cases in women age >50 years are predicted to rise by 60% in the next two decades, yet this group are less likely to attend for screening than younger women. AIM: To seek novel solutions to the ch... Read More about Challenges and opportunities for cervical screening in women over the age of 50 years: a qualitative study.

Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women (2022)
Journal Article
Bravington, A., Chen, H., Dyson, J., Jones, L., Dalgliesh, C., Bryan, A., Patnick, J., & Macleod, U. (2022). Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women. BMC health services research, 22(1), Article 610. https://doi.org/10.1186/s12913-022-07926-2

Background: Previous screening interventions have demonstrated a series of features related to social determinants which have increased uptake in targeted populations, including the assessment of health beliefs and barriers to screening attendance as... Read More about Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women.

A qualitative exploration of women's perspectives and acceptability of including new cancer awareness information in all‐clear breast or cervical screening results (2022)
Journal Article
Bamidele, O. O., Green, T., Tookey, S., Walabyeki, J., & Macleod, U. (2022). A qualitative exploration of women's perspectives and acceptability of including new cancer awareness information in all‐clear breast or cervical screening results. European Journal of Cancer Care, https://doi.org/10.1111/ecc.13574

Objective: This study explored women's perspectives on the acceptability of including new cancer information with an all-clear breast or cervical screening result letter (using ovarian cancer as a case study). Methods: In 2016, six focus group discus... Read More about A qualitative exploration of women's perspectives and acceptability of including new cancer awareness information in all‐clear breast or cervical screening results.

Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis (2022)
Journal Article
Chand, C. P., Greenley, S., Macleod, U., Lind, M., Barton, R., & Kelly, C. (2022). Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2021-003356

Background: Palliative radiotherapy (PRT) is an effective way of reducing symptoms caused by advanced incurable cancer. Several studies have investigated factors that contribute to inequalities in access to PRT; distance to a radiotherapy centre has... Read More about Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis.

The PEOPLE-HULL Study: improving help-seeking for lung symptoms in Hull. Trial registration. (2021)
Data
Mitchell, L., Macleod, U., & Walabyeki, J. (2021). The PEOPLE-HULL Study: improving help-seeking for lung symptoms in Hull. Trial registration. [Data]. https://doi.org/10.1186/ISRCTN28517662

Background and study aims:
More people are diagnosed with and die from lung cancer in Hull than any other place in Yorkshire. The main reason for this is related to lung cancers being diagnosed at a time when they are too advanced to be eligible for... Read More about The PEOPLE-HULL Study: improving help-seeking for lung symptoms in Hull. Trial registration..

A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study (2021)
Journal Article
Clark, J., Amoakwa, E., Wright-Hughes, A., Blenkinsopp, J., Currow, D. C., Meads, D., Farrin, A., Allgar, V., Macleod, U., & Johnson, M. (2021). A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study. PLoS ONE, 16(1), Article e0245647. https://doi.org/10.1371/journal.pone.0245647

Background People with cancer often have unidentified symptoms and social care needs. The Needs Assessment Tool-Cancer (NAT-C) is a validated, structured method of assessing patient/ carer concerns and prompting action, to address unmet need. Aims As... Read More about A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study.

Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care in a targeted population at risk (2020)
Journal Article
Crosbie, P. A., Gabe, R., Simmonds, I., Kennedy, M., Rogerson, S., Ahmed, N., Baldwin, D. R., Booton, R., Cochrane, A., Darby, M., Franks, K., Hinde, S., Janes, S. M., Macleod, U., Messenger, M., Moller, H., Murray, R. L., Neal, R. D., Quaife, S. L., Sculpher, M., …Callister, M. E. (2020). Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care in a targeted population at risk. BMJ open, 10(9), Article e037075. https://doi.org/10.1136/bmjopen-2020-037075

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. INTRODUCTION: Lung cancer is the world's leading cause of cancer death. Low-dose computed tomography (LDCT) screening reduced lung cancer mortality by 20% in the... Read More about Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care in a targeted population at risk.

REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial (2020)
Journal Article
Kendrick, T., Geraghty, A. W., Bowers, H., Stuart, B., Leydon, G., May, C., Yao, G., O'Brien, W., Glowacka, M., Holley, S., Williams, S., Zhu, S., Dewar-Haggart, R., Palmer, B., Bell, M., Collinson, S., Fry, I., Lewis, G., Griffiths, G., Gilbody, S., …Dowrick, C. (2020). REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial. Trials, 21(1), Article 419. https://doi.org/10.1186/s13063-020-04338-7

© 2020 The Author(s). Background: Around one in ten adults take antidepressants for depression in England, and their long-term use is increasing. Some need them to prevent relapse, but 30-50% could possibly stop them without relapsing and avoid adver... Read More about REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial.

'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives (2020)
Journal Article
Howell, D., Hart, R., Smith, A., MacLeod, U., Patmore, R., & Roman, E. (2020). 'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives. BMJ open, 10(2), Article e034244. https://doi.org/10.1136/bmjopen-2019-034244

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. Objectives To explore alignment of experiences before lymphoma and myeloma diagnosis with the appraisal, help seeking and diagnostic intervals in the Model of Pa... Read More about 'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives.

Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014) (2020)
Journal Article
Gadoud, A., Kane, E., Oliver, S. E., Johnson, M. J., MacLeod, U., & Allgar, V. (2020). Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014). BMJ supportive & palliative care, Article 001833. https://doi.org/10.1136/bmjspcare-2019-001833

Objectives While guidelines recommend palliative care in non-cancer conditions, this has not been widely implemented. We examined whether the recording of a palliative care approach and the numbers of hospital deaths for deceased patients with heart... Read More about Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014).

Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS (2019)
Journal Article
Jefferson, L., Atkin, K., Sheridan, R., Oliver, S., Macleod, U., Hall, G., Forbes, S., Green, T., Allgar, V., & Knapp, P. (2019). Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(689), E850-E859. https://doi.org/10.3399/bjgp19X706625

© British Journal of General Practice
Background: The 2-week-wait urgent referral policy in the UK has sought to improve cancer outcomes by accelerating diagnosis and treatment. However, around 5-7% of symptomatic referred patients cancel or do not... Read More about Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS.

Perceived colorectal cancer candidacy and the role of candidacy in colorectal cancer screening (2019)
Journal Article
Bikker, A. P., Macdonald, S., Robb, K. A., Conway, E., Browne, S., Campbell, C., Weller, D., Steele, R., & Macleod, U. (2019). Perceived colorectal cancer candidacy and the role of candidacy in colorectal cancer screening. Health, Risk and Society, 21(7-8), 352-372. https://doi.org/10.1080/13698575.2019.1680816

© 2019 Informa UK Limited, trading as Taylor & Francis Group. Screening is a well-established tool to advance earlier cancer diagnosis. We used Davison’s concept of ‘candidacy’ to explore how individuals draw on collectively constructed images of ‘... Read More about Perceived colorectal cancer candidacy and the role of candidacy in colorectal cancer screening.

Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway (2019)
Journal Article
Sheridan, R., Oliver, S. E., Hall, G., Allgar, V., Melling, P., Bolton, E., Atkin, K., Denton, D., Forbes, S., Green, T., Macleod, U., & Knapp, P. (2019). Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway. Cancer epidemiology, 63, Article 101588. https://doi.org/10.1016/j.canep.2019.101588

© 2019 The Authors Background: The ‘Two Week Wait’ policy aims to ensure patients with suspected cancer are seen within two weeks of referral. However, patient non-attendance can result in this target being missed. This study aimed to identify predic... Read More about Patient non-attendance at urgent referral appointments for suspected cancer and its links to cancer diagnosis and one year mortality: A cohort study of patients referred on the Two Week Wait pathway.

An integrated understanding of the complex drivers of emergency presentations and admissions in cancer patients: qualitative modelling of secondary-care health professionals’ experiences and views (2019)
Journal Article
Chen, H., Walabyeki, J., Johnson, M., Boland, E., Seymour, J., & Macleod, U. (2019). An integrated understanding of the complex drivers of emergency presentations and admissions in cancer patients: qualitative modelling of secondary-care health professionals’ experiences and views. PLoS ONE, 14(5), Article e0216430. https://doi.org/10.1371/journal.pone.0216430

The number of cancer-related emergency presentations and admissions has been steadily increasing in the UK. Drivers of this phenomenon are complex, multifactorial and interlinked. The main objective of this study was to understand the complexity of e... Read More about An integrated understanding of the complex drivers of emergency presentations and admissions in cancer patients: qualitative modelling of secondary-care health professionals’ experiences and views.

Facilitated group work for people with long-term conditions: a systematic review of benefits from studies of group-work interventions (2019)
Journal Article
Jackson, M., Jones, D., Dyson, J., & Macleod, U. (2019). Facilitated group work for people with long-term conditions: a systematic review of benefits from studies of group-work interventions. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(682), E363-E372. https://doi.org/10.3399/bjgp19X702233

Background: About 15.4 million people in the UK live with a long-term condition. Of the health and social care spend, 70% is invested in caring for this population. Evidence suggests that group-work interventions offer patient support, improved outco... Read More about Facilitated group work for people with long-term conditions: a systematic review of benefits from studies of group-work interventions.

Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences (2019)
Journal Article
Howell, D. A., Hart, R. I., Smith, A. G., Roman, E., Macleod, U., & Patmore, R. (2019). Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(679), E134-E145. https://doi.org/10.3399/bjgp19X701009

© British Journal of General Practice. Background Expediting cancer diagnosis is widely perceived as one way to improve patient outcomes. Evidence indicates that lymphoma diagnosis is often delayed, yet understanding of issues influencing this is inc... Read More about Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences.

Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study (2019)
Journal Article
Cunningham, Y., Wyke, S., Blyth, K. G., Rigg, D., Macdonald, S., Macleod, U., Harrow, S., Robb, K. A., & Whitaker, K. L. (2019). Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study. Psycho-oncology, 28(4), 718-725. https://doi.org/10.1002/pon.5005

© 2019 The Authors. Psycho-Oncology Published by John Wiley & Sons Ltd. Objective: The incidence of lung cancer is four times higher in people with chronic obstructive pulmonary disease (COPD) compared with the general population. Promotion of a sh... Read More about Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study.

Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK (2019)
Journal Article
Allgar, V. L., Oliver, S. E., Chen, H., Oviasu, O., Johnson, M. J., & Macleod, U. (2019). Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK. Cancer epidemiology, 59, 37-45. https://doi.org/10.1016/j.canep.2019.01.008

© 2019 Elsevier Ltd Background: England has significantly higher mortality risks due to Head and Neck Cancer (HNC) compared with other European countries. Early diagnosis is important as it is likely to increase early-stage diagnosis and improve surv... Read More about Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK.

Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal? (2019)
Journal Article
Macdonald, S., Conway, E., Bikker, A., Browne, S., Robb, K., Campbell, C., Steele, R. J., Weller, D., & Macleod, U. (2019). Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?. Social science & medicine, 223, 31-39. https://doi.org/10.1016/j.socscimed.2018.12.034

© 2019 Elsevier Ltd Though new or altered bodily sensations are a common occurrence they rarely transition to biomedically defined symptoms. When they do, sensations are subject to an appraisal process that can culminate in help-seeking. The transiti... Read More about Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?.