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All Outputs (21)

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials (2022)
Journal Article
Dawed, A. Y., Mari, A., Brown, A., McDonald, T. J., Li, L., Wang, S., …Jonsson, A. (2023). Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials. Lancet Diabetes and Endocrinology, 11(1), 33-41. https://doi.org/10.1016/S2213-8587%2822%2900340-0

Background: In the treatment of type 2 diabetes, GLP-1 receptor agonists lower blood glucose concentrations, body weight, and have cardiovascular benefits. The efficacy and side effects of GLP-1 receptor agonists vary between people. Human pharmacoge... Read More about Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials.

Outdoor Microplastic Analysis Using Inlet Filters from an NOx Regulatory Air Quality Monitoring Device (2022)
Journal Article
Jenner, L. C., Kureshi, R. R., White, D., Chapman, E., Sadofsky, L. R., & Rotchell, J. M. (2022). Outdoor Microplastic Analysis Using Inlet Filters from an NOx Regulatory Air Quality Monitoring Device. Atmosphere, 13(12), Article 2017. https://doi.org/10.3390/atmos13122017

Atmospheric microplastics (MPs) are a ubiquitous environmental contaminant of emerging concern. Sampling methods provide information relating to surface area concentration and MP characteristics, without direct comparison with routinely measured stan... Read More about Outdoor Microplastic Analysis Using Inlet Filters from an NOx Regulatory Air Quality Monitoring Device.

Microplastics in the surgical environment (2022)
Journal Article
Field, D. T., Green, J. L., Bennett, R., Jenner, L. C., Sadofsky, L., Chapman, E., …Rotchell, J. M. (2022). Microplastics in the surgical environment. Environment International, 170, Article 107630. https://doi.org/10.1016/j.envint.2022.107630

Atmospheric microplastics (MPs) have been consistently detected within indoor and outdoor air samples. Locations with high human activity are reported to have high MP levels. The aim was to quantify and characterise the MPs present within the surgica... Read More about Microplastics in the surgical environment.

Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills (2022)
Journal Article
White, L. J., Rose, M., Lawson, M., Joyce, D., Smith, A. M., Thomas, G. H., …Pownall, M. E. (2022). Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills. Biology Open, 11(11), Article bio059575. https://doi.org/10.1242/bio.059575

Most fish excrete their nitrogenous waste across the gills as ammonia through the activity of the Rhesus glycoprotein ammonium transporters. In contrast, fish of the subgenus Alcolapia (Oreochromis) are the only vertebrates that survive the extreme c... Read More about Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills.

Sex and gametogenesis stage are strong drivers of gene expression in Mytilus edulis exposed to environmentally relevant plasticiser levels and pH 7.7 (2022)
Journal Article
Mincarelli, L., Chapman, E. C., Rotchell, J. M., Turner, A., & Wollenberg Valero, K. C. (in press). Sex and gametogenesis stage are strong drivers of gene expression in Mytilus edulis exposed to environmentally relevant plasticiser levels and pH 7.7. Environmental science and pollution research, https://doi.org/10.1007/s11356-022-23801-3

Plastic pollution and changes in oceanic pH are both pressing environmental issues. Little emphasis, however, has been placed on the influence of sex and gametogenesis stage when investigating the effects of such stressors. Here, we examined histolog... Read More about Sex and gametogenesis stage are strong drivers of gene expression in Mytilus edulis exposed to environmentally relevant plasticiser levels and pH 7.7.

A novel method for identifying coded tags recorded on aquatic acoustic monitoring systems (2022)
Journal Article
Lowe, C. D., Tregenza, N. J., Allen, C. J., Blow, G. E., Nuuttila, H., Bertelli, C. M., …Clarke, D. R. (2022). A novel method for identifying coded tags recorded on aquatic acoustic monitoring systems. Environmental monitoring and assessment, 194(11), Article 806. https://doi.org/10.1007/s10661-022-10500-2

Aquatic biotelemetry increasingly relies on using acoustic transmitters ('tags') that enable passive detection of tagged animals using fixed or mobile receivers. Both tracking methods are resource-limited, restricting the spatial area in which moveme... Read More about A novel method for identifying coded tags recorded on aquatic acoustic monitoring systems.

Toward a decade of ocean science for sustainable development through acoustic animal tracking (2022)
Journal Article
Alós, J., Aarestrup, K., Abecasis, D., Afonso, P., Alonso‐Fernandez, A., Aspillaga, E., …Villegas-Ríos, D. (in press). Toward a decade of ocean science for sustainable development through acoustic animal tracking. Global change biology, https://doi.org/10.1111/gcb.16343

The ocean is a key component of the Earth's dynamics, providing a great variety of ecosystem services to humans. Yet, human activities are globally changing its structure and major components, including marine biodiversity. In this context, the Unite... Read More about Toward a decade of ocean science for sustainable development through acoustic animal tracking.

Spatio-temporal monitoring of lake fish spawning activity using environmental DNA metabarcoding (2022)
Journal Article
Di Muri, C., Lawson Handley, L., Bean, C. W., Benucci, M., Harper, L. R., James, B., …Hänfling, B. (2023). Spatio-temporal monitoring of lake fish spawning activity using environmental DNA metabarcoding. Environmental DNA, 5(5), 849-860. https://doi.org/10.1002/edn3.343

Determining the timing and location of fish reproductive events is crucial for the implementation of correct management and conservation schemes. Conventional methods used to monitor these events are often unable to assess the spawning activity direc... Read More about Spatio-temporal monitoring of lake fish spawning activity using environmental DNA metabarcoding.

How do readers at different career stages approach reading a scientific research paper? A case study in the biological sciences (2022)
Journal Article
Hubbard, K. E., Dunbar, S., Peasland, E. L., Solly, J., & Poon, J. (in press). How do readers at different career stages approach reading a scientific research paper? A case study in the biological sciences. International Journal of Science Education, Part B: Communication and Public Engagement, https://doi.org/10.1080/21548455.2022.2078010

Reading primary research literature is an essential skill for scientists. However, the high complexity of research papers may pose a barrier to the development of scientific literacy. In semi-structured interviews, we explore how 33 biologists includ... Read More about How do readers at different career stages approach reading a scientific research paper? A case study in the biological sciences.

A review of volunteers’ motivations to monitor and control invasive alien species (2022)
Journal Article
Anđelković, A., Lawson Handley, L., Marchante, E., Adriaens, T., Brown, P., Tricarico, E., & Verbrugge, L. (2022). A review of volunteers’ motivations to monitor and control invasive alien species. Neobiota, 73, 153-175. https://doi.org/10.3897/neobiota.73.79636

People make an important contribution to the study and management of biological invasions, as many monitoring and control projects rely heavily on volunteer assistance. Understanding the reasons why people participate in such projects is critical for... Read More about A review of volunteers’ motivations to monitor and control invasive alien species.

The ‘Tea Test’ - A mobile phone based spectrophotometer protocol to introduce biochemical methods independent of the laboratory (2022)
Journal Article
Hubbard, K., Birycka, M., Britton, M., Coates, J., Coxon, I., Jackson, C., …Worsley, B. (in press). The ‘Tea Test’ - A mobile phone based spectrophotometer protocol to introduce biochemical methods independent of the laboratory. Journal of Biological Education, https://doi.org/10.1080/00219266.2022.2072934

Providing hands-on practical education without access to laboratories during the Covid-19 pandemic has required creativity and innovation. In this paper, co-authored by academic staff and students, we describe an at-home mobile phone based ‘spectroph... Read More about The ‘Tea Test’ - A mobile phone based spectrophotometer protocol to introduce biochemical methods independent of the laboratory.

Becoming nose-blind—Climate change impacts on chemical communication (2022)
Journal Article
Roggatz, C. C., Saha, M., Blanchard, S., Schirrmacher, P., Fink, P., Verheggen, F., & Hardege, J. D. (2022). Becoming nose-blind—Climate change impacts on chemical communication. Global change biology, https://doi.org/10.1111/gcb.16209

Chemical communication via infochemicals plays a pivotal role in ecological interactions, allowing organisms to sense their environment, locate predators, food, habitats, or mates. A growing number of studies suggest that climate change-associated st... Read More about Becoming nose-blind—Climate change impacts on chemical communication.

Diet of Mesozoic toothed birds (Longipterygidae) inferred from quantitative analysis of extant avian diet proxies (2022)
Journal Article
Miller, C., Pittman, M., Wang, X., Zheng, X., & Bright, J. A. (2022). Diet of Mesozoic toothed birds (Longipterygidae) inferred from quantitative analysis of extant avian diet proxies. BMC biology, 20(1), Article 101. https://doi.org/10.1186/s12915-022-01294-3

Background: Birds are key indicator species in extant ecosystems, and thus we would expect extinct birds to provide insights into the nature of ancient ecosystems. However, many aspects of extinct bird ecology, particularly their diet, remain obscure... Read More about Diet of Mesozoic toothed birds (Longipterygidae) inferred from quantitative analysis of extant avian diet proxies.

Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera (2022)
Journal Article
Clark, B., Elkin, J., Marconi, A., Turner, G. F., Smith, A. M., Joyce, D., …Santos, M. E. (2022). Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera. Royal Society Open Science, 9(4), Article 220077. https://doi.org/10.1098/rsos.220077

Identifying genetic loci underlying trait variation provides insights into the mechanisms of diversification, but demonstrating causality and characterizing the role of genetic loci requires testing candidate gene function, often in non-model species... Read More about Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera.

Detection of microplastics in human lung tissue using μFTIR spectroscopy (2022)
Journal Article
Jenner, L. C., Rotchell, J. M., Bennett, R. T., Cowen, M., Tentzeris, V., & Sadofsky, L. (2022). Detection of microplastics in human lung tissue using μFTIR spectroscopy. The Science of the total environment, 831, Article 154907. https://doi.org/10.1016/j.scitotenv.2022.154907

Airborne microplastics (MPs) have been sampled globally, and their concentration is known to increase in areas of high human population and activity, especially indoors. Respiratory symptoms and disease following exposure to occupational levels of MP... Read More about Detection of microplastics in human lung tissue using μFTIR spectroscopy.

Global biogeographic patterns of avian morphological diversity (2022)
Journal Article
Hughes, E. C., Edwards, D. P., Bright, J. A., Capp, E. J., Cooney, C. R., Varley, Z. K., & Thomas, G. H. (2022). Global biogeographic patterns of avian morphological diversity. Ecology letters, 25(3), 598-610. https://doi.org/10.1111/ele.13905

Understanding the biogeographical patterns, and evolutionary and environmental drivers, underpinning morphological diversity are key for determining its origins and conservation. Using a comprehensive set of continuous morphological traits extracted... Read More about Global biogeographic patterns of avian morphological diversity.

Outdoor atmospheric microplastics within the Humber region (United Kingdom): Quantification and chemical characterisation of deposited particles present (2022)
Journal Article
Jenner, L., Sadofsky, L., Danopoulos, E., Chapman, E., White, D., Jenkins, R., & Rotchell, J. M. (2022). Outdoor atmospheric microplastics within the Humber region (United Kingdom): Quantification and chemical characterisation of deposited particles present. Atmosphere, 13(2), Article 265. https://doi.org/10.3390/atmos13020265

Atmospheric microplastics (MPs) have been consistently captured within air samples on a global scale. Locations with high human activity are reported to have high MP levels. An urban sampling site in the Humber region (U.K.) has been sampled over a 1... Read More about Outdoor atmospheric microplastics within the Humber region (United Kingdom): Quantification and chemical characterisation of deposited particles present.

Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study (2022)
Journal Article
Zhu, J., Li, J., Chapman, E. C., Shi, H., Ciocan, C. M., Chen, K., …Rotchell, J. M. (in press). Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study. Bulletin of Environmental Contamination and Toxicology, https://doi.org/10.1007/s00128-022-03461-2

This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36ng/... Read More about Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study.

Individual movement variation in upstream-migrating sea lamprey Petromyzon marinus in a highly fragmented river (2022)
Journal Article
Davies, P., Britton, J. R., Nunn, A. D., Dodd, J. R., Bainger, C., Velterop, R., & Bolland, J. D. (in press). Individual movement variation in upstream-migrating sea lamprey Petromyzon marinus in a highly fragmented river. Freshwater biology, https://doi.org/10.1111/fwb.13869

Anthropogenic reductions in riverine connectivity can severely impede the migrations of anadromous species. In fragmented rivers, successful migrations depend on the ability of migrants to negotiate barriers or locate alternative passage routes. Howe... Read More about Individual movement variation in upstream-migrating sea lamprey Petromyzon marinus in a highly fragmented river.