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Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study

Zhu, Jingmin; Li, Jiana; Chapman, Emma C.; Shi, Huahong; Ciocan, Corina M.; Chen, Kai; Shi, Xiaodong; Zhou, Jun Liang; Sun, Peiying; Zheng, Yueyao; Rotchell, Jeanette M.

Authors

Jingmin Zhu

Jiana Li

Emma C. Chapman

Huahong Shi

Corina M. Ciocan

Kai Chen

Xiaodong Shi

Jun Liang Zhou

Peiying Sun

Yueyao Zheng



Abstract

This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36ng/L, < LOD-3.88ng/g wet weight of tissue for BPA) relative to worldwide freshwater environments, but high oocyte follicle atresia incidences (up to 26.6%) occurred at selected sites. Expression of estrogen-responsive ER2 was significantly increased in males relative to females at sites with high atresia incidences in females. A second estrogen-responsive gene, V9, was significantly increased at two sites in April in females relative to males; the opposite was true for the remaining two sites. Apoptosis-specific genes (Bcl-2, fas) showed elevated expression in males relative to females at the site with the highest atresia incidence. These results provide coastal estrogen levels and the utility of several estrogen-specific molecular-level markers for marine mussels.

Citation

Zhu, J., Li, J., Chapman, E. C., Shi, H., Ciocan, C. M., Chen, K., …Rotchell, J. M. (in press). Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study. Bulletin of Environmental Contamination and Toxicology, https://doi.org/10.1007/s00128-022-03461-2

Journal Article Type Article
Acceptance Date Jan 11, 2022
Online Publication Date Jan 24, 2022
Deposit Date Jan 12, 2022
Publicly Available Date Oct 27, 2022
Journal Bulletin of Environmental Contamination and Toxicology
Print ISSN 0007-4861
Electronic ISSN 1432-0800
Publisher Springer (part of Springer Nature)
Peer Reviewed Peer Reviewed
DOI https://doi.org/10.1007/s00128-022-03461-2
Keywords Mytilus; Estrogen; Atresia; Apoptosis
Public URL https://hull-repository.worktribe.com/output/3910318

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Copyright Statement
© The Author(s) 2022.
Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.



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