Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study
Zhu, Jingmin; Li, Jiana; Chapman, Emma C.; Shi, Huahong; Ciocan, Corina M.; Chen, Kai; Shi, Xiaodong; Zhou, Jun Liang; Sun, Peiying; Zheng, Yueyao; Rotchell, Jeanette M.
Emma C. Chapman
Corina M. Ciocan
Jun Liang Zhou
Professor Jeanette Rotchell J.Rotchell@hull.ac.uk
Professor and Associate Dean for Research and Enterprise
This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36ng/L, < LOD-3.88ng/g wet weight of tissue for BPA) relative to worldwide freshwater environments, but high oocyte follicle atresia incidences (up to 26.6%) occurred at selected sites. Expression of estrogen-responsive ER2 was significantly increased in males relative to females at sites with high atresia incidences in females. A second estrogen-responsive gene, V9, was significantly increased at two sites in April in females relative to males; the opposite was true for the remaining two sites. Apoptosis-specific genes (Bcl-2, fas) showed elevated expression in males relative to females at the site with the highest atresia incidence. These results provide coastal estrogen levels and the utility of several estrogen-specific molecular-level markers for marine mussels.
Zhu, J., Li, J., Chapman, E. C., Shi, H., Ciocan, C. M., Chen, K., …Rotchell, J. M. (in press). Gonadal atresia, estrogen-responsive, and apoptosis-specific mRNA expression in marine mussels from the East China coast: a preliminary study. Bulletin of Environmental Contamination and Toxicology, https://doi.org/10.1007/s00128-022-03461-2
|Journal Article Type||Article|
|Acceptance Date||Jan 11, 2022|
|Online Publication Date||Jan 24, 2022|
|Deposit Date||Jan 12, 2022|
|Publicly Available Date||Oct 27, 2022|
|Journal||Bulletin of Environmental Contamination and Toxicology|
|Publisher||Springer (part of Springer Nature)|
|Peer Reviewed||Peer Reviewed|
|Keywords||Mytilus; Estrogen; Atresia; Apoptosis|
© The Author(s) 2022.
Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
You might also like
Detection of microplastics in human lung tissue using ?FTIR spectroscopy
Susceptibility of polar cod (Boreogadus saida) to a model carcinogen