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Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens (2000)
Journal Article
Nikitenko, L. L., Lloyd, B. H., Rudland, P. S., Fear, S., & Barraclough, R. (2000). Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens. International journal of cancer. Journal international du cancer, 86(2), 219-228. https://doi.org/10.1002/%28SICI%291097-0215%2820000415%2986%3A2%3C219%3A%3AAID-IJC11%3E3.0.CO%3B2-7

Rodent S 100A4 (p9Ka) induces a metastatic phenotype in benign rat mammary tumour cells and cooperates with the neu oncogene to produce metastatic tumours in a transgenic mouse model system. Human S 100A4 possesses similar metastasis-inducing propert... Read More about Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens.

Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cells (2000)
Journal Article
Harley, S. L., Sturge, J., & Powell, J. T. (2000). Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(3), 652-658. https://doi.org/10.1161/01.ATV.20.3.652

It has been reported that fibrinogen may act as a bridging ligand, binding to intercellular adhesion molecule-1 (ICAM-1) on human umbilical vein endothelial cells and to Mac-1 on THP-1 cells (a monocytic cell line) to increase adhesion. In this study... Read More about Regulation by fibrinogen and its products of intercellular adhesion molecule-1 expression in human saphenous vein endothelial cells.

Immunocytochemical and in situ hybridization studies of the distribution of calbindin D(9k) in the bovine placenta throughout pregnancy (1998)
Journal Article
Nikitenko, L., Morgan, G., Kolesnikov, S. I., & Wooding, F. B. (1998). Immunocytochemical and in situ hybridization studies of the distribution of calbindin D(9k) in the bovine placenta throughout pregnancy. Journal of Histochemistry and Cytochemistry, 46(5), 679-688. https://doi.org/10.1177/002215549804600513

The fetus must transport considerable and increasing amounts of calcium across the placental trophoblast epithelium to support growth and development and bone formation. Active calcium transport across epithelia has been shown to correlate with calbi... Read More about Immunocytochemical and in situ hybridization studies of the distribution of calbindin D(9k) in the bovine placenta throughout pregnancy.

The effects of hypo- and hyperglycemia during lipolysis-like conditions on bovine oocyte maturation, subsequent embryo developmental and glucose metabolism
Presentation / Conference Contribution
Sturmey, R., Andries, S., Bols, P., De Bie, J., Desmet, K., Leroy, J., & Marei, W. The effects of hypo- and hyperglycemia during lipolysis-like conditions on bovine oocyte maturation, subsequent embryo developmental and glucose metabolism

Abstract of a conference paper presented at the 31st meeting of the European Embryo Transfer Associaton, 11-12 September 2015, Ghent, Belgium.

Understanding the use of wood-burning stoves in the East Riding - a postnote
Report
Oresanya, T. O., Norfolk, K., Mullen, S., Taylor, J., Durham, G., & Beltran-Alvarez, P. Understanding the use of wood-burning stoves in the East Riding - a postnote. East Riding of Yorkshire Council

Opening paragraph:
Wood-burning is particularly common in the East Riding of Yorkshire. Wood-burning stoves are used by a higher percentage of households in the East Riding, compared to average use in England as a whole.
Wood burning can lead to po... Read More about Understanding the use of wood-burning stoves in the East Riding - a postnote.

Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine
Presentation / Conference Contribution
Bower, R., Green, V., Kuvshinov, D., Crank, S., Stafford, N., & Greenman, J. (2016, October). Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine. Presented at 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland

The current paper details a succinct characterisation of an in-house designed microfluidic culture device. The maintenance of tissue viability was determined by studying single cells, following dissociation, of head and neck tumour pre and post cultu... Read More about Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine.

Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions
Presentation / Conference Contribution
Sturge, J. (2009, May). Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions. Presented at BIT‘s 2nd Annual World Cancer Congess 2009, Beijing

A major clinical complication in patients with advanced prostate cancer is metastasis to bone where osteoblastic and/or osteoclastic activity results in a highly destructive tissue remodelling process.Recent in vivo studies have identified important... Read More about Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions.

Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils
Presentation / Conference Contribution
Juliana, P., Marco, L., Célia, C., Lígia, S., & Pires, I. M. D. S. (2014, July). Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils. Presented at IMMR | International Meeting on Marine Research 2014, Peniche, Portugal

An essential oil (EO) is defined internationally as the product obtained by hydrodistillation, of a plant or some parts of it. They are aromatic oily liquids, volatile, characterized by a strong odour, rarely coloured, and generally with a lower dens... Read More about Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils.

Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability
Presentation / Conference Contribution
Poças, J., Lemos, M., Cabral, C., Cavaleiro, C., Cruz, M., Salgueiro, L., & Pires, I. (2014, August). Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability. Presented at 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Guimarães, Portugal

Ridolfia segetum Moris, commonly known as corn parsley, false fennel, or false caraway, is distributed throughout the Mediterranean region. It belongs to the Apiaceae (carrot or parsley family), which includes well-known aromatic and medicinal plants... Read More about Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability.

Calbindin-D(9κ) protein and mRNA localisation in bovine placenta
Presentation / Conference Contribution
Nikitenko, L., Morgan, G., & Wooding, F. B. Calbindin-D(9κ) protein and mRNA localisation in bovine placenta. Presented at Annual General Meeting of the Anatomical Society of Great Britain and Ireland, 17-19 Dec 1996, St George’s Hospital Medical School, University of London

Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study
Presentation / Conference Contribution
Hillmen, P., Cairns, D. A., Bloor, A. J. C., Allsup, D., Cwynarski, K., Pettitt, A., Paneesha, S., Fox, C. P., Eyre, T. A., Forconi, F., Elmusharaf, N., Kennedy, B., Gribben, J. G., Pemberton, N., Sheehy, O., Preston, G., Schuh, A., Howard, D., Hockaday, A., Jackson, S., …Munir, T. Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study. Presented at 65th ASH Annual Meeting and Exposition, San Diego, CA

Introduction: Ibrutinib (I), an irreversible Btk inhibitor, and venetoclax (V), a Bcl-2 inhibitor, improve CLL outcomes in trials compared to chemoimmunotherapy. I and V target two key pathophysiological pathways in CLL and should be synergistic. Thi... Read More about Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study.

Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict <0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial
Presentation / Conference Contribution
Rawstron, A., Webster, N., Dalal, S., de Tute, R. M., Bell, S., Cairns, D. A., Girvan, S., Greatorex, N., Hockaday, A., Jackson, S., Phillips, D., Stones, D., Allsup, D., Bloor, A. J. C., Sarma, A., Varghese, A. M., Munir, T., & Hillmen, P. Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict <0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial. Presented at 65th ASH Annual Meeting and Exposition, San Diego, CA

Molecular Analysis at Relapse of Patients Treated on the Ibrutinib and Rituximab Arm of the National Multi-Centre Phase III FLAIR Study in Previously Untreated CLL Patients
Presentation / Conference Contribution
Sarma, A., Evans, C., Dalal, S., Webster, N., Rawstron, A., Shingles, J., Newton, D., Cairns, D. A., Glover, P., Grand, T., Warren, H., Bell, S., Girvan, S., Greatorex, N., Hockaday, A., Jackson, S., Phillips, D., Stones, D., Allsup, D., Bloor, A. J. C., …Hillmen, P. Molecular Analysis at Relapse of Patients Treated on the Ibrutinib and Rituximab Arm of the National Multi-Centre Phase III FLAIR Study in Previously Untreated CLL Patients. Presented at 65th ASH Annual Meeting And Exposition, San Diego, CA