Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine
Bower, Ruth; Green, Victoria; Kuvshinov, Dmitriy; Crank, Stephen; Stafford, Nicholas; Greenman, John
Professor John Greenman J.Greenman@hull.ac.uk
Professor of Tumour Immunology
The current paper details a succinct characterisation of an in-house designed microfluidic culture device. The maintenance of tissue viability was determined by studying single cells, following dissociation, of head and neck tumour pre and post culture. In addition, irradiation schedules have been elucidated using cell lines for transfer to the on-chip model. This provides a platform for a move towards personalised medicine in which the interrogation of biopsies on-chip will provide an evidence-base for treatment. (Fig 1.).
|Start Date||Oct 9, 2016|
|Publication Date||Jan 1, 2016|
|APA6 Citation||Bower, R., Green, V., Kuvshinov, D., Crank, S., Stafford, N., & Greenman, J. (2016). Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine|