Soy isoflavones improve cardiovascular disease risk markers in women during 1 the early menopause 2 1

Sathyapalan, Thozhukat; Aye, Myint; Rigby, Alan S; Thatcher, Natalie J; Dargham, Soha R; Kilpatrick, Eric S; Atkin, Stephen L

doi:10.1016/j.numecd.2018.03.007

Foundations of respiratory medicine (2018)
Book
(2018). S. Hart, & M. Greenstone (Eds.), Foundations of respiratory medicine. Cham: Springer. https://doi.org/10.1007/978-3-319-94127-1

This book meets the need for a resource that covers the core knowledge required to pass the SCE exam, which includes the broad field of respiratory medicine. This book is also highly applicable to core medical trainees sitting their MRCP examinations... Read More about Foundations of respiratory medicine.

Occurrence of deoxynivalenol in an elderly cohort in the UK: a biomonitoring approach (2018)
Journal Article
Papageorgiou, M., Wells, L., Williams, C., White, K. L., De Santis, B., Liu, Y., …Sathyapalan, T. (2018). Occurrence of deoxynivalenol in an elderly cohort in the UK: a biomonitoring approach. Food Additives and Contaminants: Part A: Chemistry, Analysis, Control, Exposure and Risk Assessment, 35(10), 2032-2044. https://doi.org/10.1080/19440049.2018.1508890

Deoxynivalenol (DON) is a Fusarium toxin, to which humans are frequently exposed via diet. Although the elderly are speculated to be sensitive to the toxic effects of DON as a result of age-related conditions, disease and altered DON metabolism, ther... Read More about Occurrence of deoxynivalenol in an elderly cohort in the UK: a biomonitoring approach.

The impact of heart failure and chronic obstructive pulmonary disease on mortality in patients presenting with breathlessness (2018)
Journal Article
Cuthbert, J. J., Kearsley, J. W., Kazmi, S., Kallvikbakka-Bennett, A., Weston, J., Davis, J., …Clark, A. L. (2019). The impact of heart failure and chronic obstructive pulmonary disease on mortality in patients presenting with breathlessness. Clinical Research in Cardiology, 108(2), 185–193. https://doi.org/10.1007/s00392-018-1342-z

© 2018, The Author(s). Background: Differentiating heart failure from chronic obstructive pulmonary disease (COPD) in a patient presenting with breathlessness is difficult but may have implications for outcome. We investigated the prognostic impact o... Read More about The impact of heart failure and chronic obstructive pulmonary disease on mortality in patients presenting with breathlessness.

Successful treatment of resistant Burkholderia multivorans infection in a patient with cystic fibrosis using ceftazidime/avibactam plus aztreonam (2018)
Journal Article
Barlow, G., & Morice, A. (2018). Successful treatment of resistant Burkholderia multivorans infection in a patient with cystic fibrosis using ceftazidime/avibactam plus aztreonam. The journal of antimicrobial chemotherapy, 73(8), 2270-2271. https://doi.org/10.1093/jac/dky136

CAMERA - complete assessment of elderly patients with cancer: A non-randomised feasibility study (2018)
Journal Article
Jackson, G., Gabe, R., Johnson, M., Date, K., Harman, D., Maraveyas, A., …Lind, M. J. (2019). CAMERA - complete assessment of elderly patients with cancer: A non-randomised feasibility study. Journal of Geriatric Oncology, 10(1), 175-177. https://doi.org/10.1016/j.jgo.2018.07.005

One of the primary risk factors in the development of cancer is older age. The demographic shift to an ageing population has given rise to an increased number of older patients with cancer. The extreme heterogeneity within this population renders app... Read More about CAMERA - complete assessment of elderly patients with cancer: A non-randomised feasibility study.

Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters (2018)
Journal Article
Heffernan, A., Cunningham, T., Drage, D., Aylward, L., Thompson, K., Vijayasarathy, S., …Sathyapalan, T. (2018). Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters. International Journal of Hygiene and Environmental Health, 221(7), 1068-1075. https://doi.org/10.1016/j.ijheh.2018.07.009

© 2018 Women with polycystic ovarian syndrome (PCOS) undergoing treatment for infertility could be a sensitive subpopulation for endocrine effects of exposure to perfluorinated alkyl acids (PFAAs), persistent organic pollutants with potential endocri... Read More about Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters.

Anti reflux surgery (2018)
Book Chapter
Rai, Z., Morice, A. H., & Sedman, P. (2018). Anti reflux surgery. In A. H. Morice, & P. W. Dettmar (Eds.), Reflux Aspiration and Lung Disease (357-363). Cham: Springer. https://doi.org/10.1007/978-3-319-90525-9_28

Surgery may be necessary to control gross reflux disease, particularly when anatomical abnormalities underlie the pathophysiology. Treatment is generally less successful when directed at isolated airway reflux and aspiration since the refluxate consi... Read More about Anti reflux surgery.

Diagnostic confusion through the ages (2018)
Book Chapter
Morice, A. H. (2018). Diagnostic confusion through the ages. In A. H. Morice, & P. W. Dettmar (Eds.), Reflux Aspiration and Lung Disease (3-8). Cham: Springer. https://doi.org/10.1007/978-3-319-90525-9_1

XII AIST 2018 Conference: "the thousand faces of cough: Clinical and therapeutic updates" (2018)
Journal Article
Zanasi, A., Morselli-Labate, A. M., Mazzolini, M., Mastroroberto, M., Dal Negro, R. W., Poliacek, I., …Tursi, F. (2018). XII AIST 2018 Conference: "the thousand faces of cough: Clinical and therapeutic updates". Multidisciplinary Respiratory Medicine, 13(1), Article 17. https://doi.org/10.1186/s40248-018-0130-y

© 2018 The Author(s). This paper summarizes the presentations submitted for publication of the 12th AIST National Congress (Associazione Italiana Studio Tosse/Italian Association for Cough Study) entitled "The thousand facets of cough. A clinical and... Read More about XII AIST 2018 Conference: "the thousand faces of cough: Clinical and therapeutic updates".

Low serum chloride in patients with chronic heart failure: clinical associations and prognostic significance (2018)
Journal Article
Cuthbert, J. J., Pellicori, P., Rigby, A., Pan, D., Kazmi, S., Shah, P., & Clark, A. L. (2018). Low serum chloride in patients with chronic heart failure: clinical associations and prognostic significance. European journal of heart failure, 20(10), 1426-1435. https://doi.org/10.1002/ejhf.1247

© 2018 The Authors. European Journal of Heart Failure © 2018 European Society of Cardiology Background: Low serum chloride is common in patients with chronic heart failure (CHF) and is associated with worse outcomes. We investigated the clinical and... Read More about Low serum chloride in patients with chronic heart failure: clinical associations and prognostic significance.

Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure (2018)
Journal Article
Zhang, J., Pellicori, P., Pan, D., Dierckx, R., Clark, A. L., & Cleland, J. (2018). Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure. International journal of cardiology, 269, 196-200. https://doi.org/10.1016/j.ijcard.2018.06.070

Background Prognostic models for patients with chronic heart failure are generally based on a single assessment but treatment is often given with the intention of changing risk; re- evaluation of risk is an important aspect of care. The prognostic va... Read More about Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure.

Investigation of pituitary disease (2018)
Book Chapter
Sathyapalan, T., & Atkin, S. L. (2018). Investigation of pituitary disease. In J. Watkinson, & R. Clarke (Eds.), Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, vol.1 (915-921). (8th ed.). Boca Raton, Fla.: CRC Press. https://doi.org/10.1201/9780203731031

The close relationship between the upper respiratory tract (nose and paranasal sinuses) and the lower respiratory tract (tracheobronchial tree) is something that is manifestly observed by all practising rhinologists. There is strong epidemiological e... Read More about Investigation of pituitary disease.

Clinical evaluation of hypercalcaemia (2018)
Book Chapter
Aye, M., & Sathyapalan, T. (2018). Clinical evaluation of hypercalcaemia. In J. Watkinson, & R. Clarke (Eds.), Scott-Brown's Otorhinolaryngology and Head and Neck Surgery Volume 1: Basic Sciences, Endocrine Surgery, Rhinology (827-832). (8th ed.). Boca Raton, Fla.: CRC Press. https://doi.org/10.1201/9780203731031

Improved physiology and metabolic flux after Roux-en-Y gastric bypass is associated with temporal changes in the circulating microRNAome: A longitudinal study in humans (2018)
Journal Article
Alkandari, A., Ashrafian, H., Sathyapalan, T., Sedman, P., Darzi, A., Holmes, E., …Gooderham, N. J. (2018). Improved physiology and metabolic flux after Roux-en-Y gastric bypass is associated with temporal changes in the circulating microRNAome: A longitudinal study in humans. BMC obesity, 5(1), Article 20. https://doi.org/10.1186/s40608-018-0199-z

Background The global pandemic of obesity and the metabolic syndrome are leading causes of mortality and morbidity. Bariatric surgery leads to sustained weight loss and improves obesity-associated morbidity including remission of type 2 diabetes. Mic... Read More about Improved physiology and metabolic flux after Roux-en-Y gastric bypass is associated with temporal changes in the circulating microRNAome: A longitudinal study in humans.

Comparison of an oral factor xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism: Results of a randomized trial (SELECT-D) (2018)
Journal Article
Young, A. M., Marshall, A., Thirlwall, J., Chapman, O., Lokare, A., Hill, C., …Levine, M. (2018). Comparison of an oral factor xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism: Results of a randomized trial (SELECT-D). Journal of Clinical Oncology, 36(20), 2017-2023. https://doi.org/10.1200/JCO.2018.78.8034

© 2018 by American Society of Clinical Oncology. Purpose Venous thromboembolism (VTE) is common in patients with cancer. Long-term daily subcutaneous low molecular weight heparin has been standard treatment for such patients. The purpose of this stud... Read More about Comparison of an oral factor xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism: Results of a randomized trial (SELECT-D).

Photograph-based telemedicine: a promising tool for postoperative wound assessment in the diagnosis or exclusion of surgical site infection (2018)
Presentation / Conference
Totty, J. P., Harwood, A. E., Wallace, T., Smith, G. E., & Chetter, I. C. (2018, May). Photograph-based telemedicine: a promising tool for postoperative wound assessment in the diagnosis or exclusion of surgical site infection. Paper presented at EWMA 2018 Krakow: New frontiers in wound management, Krakow Poland

Platelet function following induced hypoglycaemia in type 2 diabetes (2018)
Journal Article
Kahal, H., Aburima, A., Spurgeon, B., Wraith, K. S., Rigby, A. S., Sathyapalan, T., …Atkin, S. L. (2018). Platelet function following induced hypoglycaemia in type 2 diabetes. Diabetes & metabolism, 44(5), 431-436. https://doi.org/10.1016/j.diabet.2018.04.004

Aim Strict glycaemic control has been associated with an increased mortality rate in subjects with type 2 diabetes (T2DM). Here we examined platelet function immediately and 24 hours following induced hypoglycaemia in people with type 2 diabetes comp... Read More about Platelet function following induced hypoglycaemia in type 2 diabetes.

Adjustment of the GRACE score by 2-hour post-load glucose improves prediction of long-term major adverse cardiac events in acute coronary syndrome in patients without known diabetes (2018)
Journal Article
George, A., John, J., Sathyapalan, T., & Chattopadhyay, S. (2018). Adjustment of the GRACE score by 2-hour post-load glucose improves prediction of long-term major adverse cardiac events in acute coronary syndrome in patients without known diabetes. European Heart Journal, 39(29), 2740-2745. https://doi.org/10.1093/eurheartj/ehy233

Aims Global Registry of Acute Coronary Events (GRACE) risk score (GRS), a powerful predictor of prognosis after ACE, does not include a glucometabolic measure. We investigate whether 2 hour post-load plasma glucose (2h-PG) could improve GRS based pro... Read More about Adjustment of the GRACE score by 2-hour post-load glucose improves prediction of long-term major adverse cardiac events in acute coronary syndrome in patients without known diabetes.

Soy isoflavones improve cardiovascular disease risk markers in women during the early menopause (2018)
Journal Article
Sathyapalan, T., Aye, M., Rigby, A. S., Thatcher, N. J., Dargham, S. R., Kilpatrick, E. S., & Atkin, S. L. (2018). Soy isoflavones improve cardiovascular disease risk markers in women during the early menopause. Nutrition, metabolism, and cardiovascular diseases : NMCD, 28(7), 691-697. https://doi.org/10.1016/j.numecd.2018.03.007

© 2018 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University Background: Hormone replacement thera... Read More about Soy isoflavones improve cardiovascular disease risk markers in women during the early menopause.

Soy isoflavones improve cardiovascular disease risk markers in women during 1 the early menopause 2 1 (2018)
Journal Article
Sathyapalan, T., Aye, M., Rigby, A. S., Thatcher, N. J., Dargham, S. R., Kilpatrick, E. S., & Atkin, S. L. (2018). Soy isoflavones improve cardiovascular disease risk markers in women during 1 the early menopause 2 1. Nutrition, metabolism, and cardiovascular diseases : NMCD, 28(7), 691-697. https://doi.org/10.1016/j.numecd.2018.03.007

Background Hormone replacement therapy may be beneficial for cardiovascular disease risk (CVR) in post-menopausal women. Soy isoflavones may act as selective estrogen receptor modulators. The aim of this study was to evaluate whether soy isoflavones... Read More about Soy isoflavones improve cardiovascular disease risk markers in women during 1 the early menopause 2 1.

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