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The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update (2021)
Journal Article
Navashenaq, J. G., Shabgah, A. G., Hedayati-Moghadam, M., Ariaee, N., Mohammadi, H., Hemmatzadeh, M., …Sahebkar, A. (2021). The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update. Life Sciences, 269, https://doi.org/10.1016/j.lfs.2021.119083

© 2021 Rheumatoid arthritis (RA) is an autoimmune disease that generally affects the joints. In the late stages of the disease, it can be associated with several complications. Although the exact etiology of RA is unknown, various studies have been p... Read More about The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update.

Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis (2021)
Journal Article
Karimi, L., Makvandi, S., Vahedian-Azimi, A., Sathyapalan, T., & Sahebkar, A. (2021). Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis. Journal of Pregnancy, 2021, 1-33. https://doi.org/10.1155/2021/8870129

Background. Based on what is known at this time, pregnant women are at an increased risk of severe illness from COVID-19 compared to nonpregnant women. Additionally, pregnant women with COVID-19 might have an increased risk of adverse pregnancy outco... Read More about Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis.

Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome (2021)
Journal Article
Moin, A. S. M., Sathyapalan, T., Diboun, I., Elrayess, M. A., Butler, A. E., & Atkin, S. L. (in press). Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome. Scientific reports, 11(1), Article 5320. https://doi.org/10.1038/s41598-021-84586-y

© 2021, The Author(s). Polycystic ovary syndrome (PCOS) women have a hypercoagulable state; however, whether this is intrinsically due to PCOS or, alternatively, a consequence of its metabolic complications is unclear. We determined plasma coagulatio... Read More about Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome.

Depression, Anxiety, and Stress Among Patients with COVID-19: A Cross-Sectional Study (2021)
Book Chapter
Moayed, M. S., Vahedian-Azimi, A., Mirmomeni, G., Rahimi-Bashar, F., Goharimoghadam, K., Pourhoseingholi, M. A., …Sahebkar, A. (2021). Depression, Anxiety, and Stress Among Patients with COVID-19: A Cross-Sectional Study. In P. C. Guest (Ed.), Clinical, Biological and Molecular Aspects of COVID-19 (229-236). Cham: Springer. https://doi.org/10.1007/978-3-030-59261-5_19

© 2021, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG. Aim: Patients with confirmed COVID-19 infection can develop several psychological consequences. Epidemiological data on mental health... Read More about Depression, Anxiety, and Stress Among Patients with COVID-19: A Cross-Sectional Study.

The Immune Response and Effectiveness of COVID-19 Therapies (2021)
Book Chapter
Tavasolian, F., Hatam, G. R., Mosawi, S. H., Saadi, M. I., Abdollahi, E., Jamialahmadi, T., …Sahebkar, A. (2021). The Immune Response and Effectiveness of COVID-19 Therapies. In P. C. Guest (Ed.), Clinical, Biological and Molecular Aspects of COVID-19 (115-126). Cham: Springer. https://doi.org/10.1007/978-3-030-59261-5_10

© 2021, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG. Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly pathogenic with r... Read More about The Immune Response and Effectiveness of COVID-19 Therapies.

Impact of the SARS-CoV-2 (COVID-19) crisis on surgical training: Global survey and a proposed framework for recovery (2021)
Journal Article
Wilson, A., Van Cleynenbreugel, B., Wellbelove, Z., Sharma, D., Sultan, J., Sanchez Salas, R., …Chetter, I. (2021). Impact of the SARS-CoV-2 (COVID-19) crisis on surgical training: Global survey and a proposed framework for recovery. BJS Open, 5(2), Article zraa051. https://doi.org/10.1093/bjsopen/zraa051

Background: The SARS-CoV-2 pandemic had a profound impact on surgical services, potentially having a detrimental impact on training opportunities. The aim of this global survey was to assess the impact of the COVID-19 crisis on surgical training and... Read More about Impact of the SARS-CoV-2 (COVID-19) crisis on surgical training: Global survey and a proposed framework for recovery.

Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection? (2021)
Journal Article
Moin, A. S. M., Sathyapalan, T., Butler, A. E., & Atkin, S. L. (2021). Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?. Frontiers in endocrinology, 12, Article 638621. https://doi.org/10.3389/fendo.2021.638621

© Copyright © 2021 Moin, Sathyapalan, Butler and Atkin. Background: Women with polycystic ovary syndrome (PCOS) often have vitamin D deficiency, a known risk factor for severe COVID-19 disease. Alveolar macrophage-derived cytokines contribute to the... Read More about Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?.

Post-COVID-19 Symptom Burden: What is Long-COVID and How Should We Manage It? (2021)
Journal Article
Sykes, D. L., Holdsworth, L., Jawad, N., Gunasekera, P., Morice, A. H., & Crooks, M. G. (2021). Post-COVID-19 Symptom Burden: What is Long-COVID and How Should We Manage It?. Lung, 199(2), 113-119. https://doi.org/10.1007/s00408-021-00423-z

© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature. The enduring impact of COVID-19 on patients has been examined in recent studies, leading to the description of Long-COVID. We report the l... Read More about Post-COVID-19 Symptom Burden: What is Long-COVID and How Should We Manage It?.

Pulmonary fibrosis: Therapeutic and mechanistic insights into the role of phytochemicals (2021)
Journal Article
Hosseini, S. A., Zahedipour, F., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (in press). Pulmonary fibrosis: Therapeutic and mechanistic insights into the role of phytochemicals. BioFactors, https://doi.org/10.1002/biof.1713

Pulmonary fibrosis (PF) is the devastating consequence of various inflammatory diseases of the lung. PF leads to a reduction of lung function, respiratory failure, and death. Several molecular pathways are involved in PF, such as inflammatory cytokin... Read More about Pulmonary fibrosis: Therapeutic and mechanistic insights into the role of phytochemicals.

Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models (2021)
Journal Article
Mohammadi, S., Abdollahi, E., Nezamnia, M., Esmaeili, S. A., Tavasolian, F., Sathyapalan, T., & Sahebkar, A. (2021). Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models. International immunopharmacology, 90, Article 107195. https://doi.org/10.1016/j.intimp.2020.107195

Since half of the genes are inherited from the paternal side, the maternal immune system has to tolerate the presence of foreign paternal antigens. Regulatory T cells facilitate the development and maintenance of peripheral tissue tolerance of the fe... Read More about Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models.

The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence (2021)
Journal Article
Abdalla, M. A., Deshmukh, H., Atkin, S., & Sathyapalan, T. (2021). The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence. Therapeutic Advances in Endocrinology and Metabolism, 12, https://doi.org/10.1177/2042018821989238

© The Author(s), 2021. Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects women of reproductive age. Metabolic consequences associated with PCOS include, but are not limited to, insulin resistance (IR), type 2... Read More about The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence.

Author response to: Comment on: Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): surgery may be the best treatment option (2021)
Journal Article
Guadalajara, H., Muñoz de Nova, J. L., Fernandez Gonzalez, S., Yiasemidou, M., Recarte Rico, M., Juez, L. D., …PIACO Collaboration Group. (2021). Author response to: Comment on: Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): surgery may be the best treatment option. British journal of surgery, 108(1), e42-e43. https://doi.org/10.1093/bjs/znaa022

A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol (2021)
Journal Article
Northgraves, M., Cohen, J., Allgar, V., Currow, D., Hart, S., Hird, K., …Hutchinson, A. (2021). A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol. ERJ Open Research, 7(1), Article 00955-2020. https://doi.org/10.1183/23120541.00955-2020

Introduction: Chronic breathlessness, persistent and disabling despite optimal treatment of underlying causes, is a prevalent and frightening symptom and is associated with many emergency presentations and admission to hospital. Breathlessness manage... Read More about A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol.

Neurokinin-1 receptor (NK-1R) antagonists: potential targets in the treatment of glioblastoma multiforme (2021)
Journal Article
Afshari, A. R., Motamed-Sanaye, A., Sabri, H., Soltani, A., Karkon-Shayan, S., Radvar, S., …Sahebkar, A. (2021). Neurokinin-1 receptor (NK-1R) antagonists: potential targets in the treatment of glioblastoma multiforme. Current medicinal chemistry, 28(24), 4877-4892. https://doi.org/10.2174/0929867328666210113165805

The current standard of care in glioblastoma multiforme (GBM), as the most morbid brain tumor, is not adequate, despite substantial progress in cancer therapy. Among patients receiving current standard treatments, including surgery, irradiation, and... Read More about Neurokinin-1 receptor (NK-1R) antagonists: potential targets in the treatment of glioblastoma multiforme.

Cardiac Injury in COVID-19: A Systematic Review (2021)
Book Chapter
Moayed, M. S., Rahimi-Bashar, F., Vahedian-Azimi, A., Sathyapalan, T., Guest, P. C., Jamialahmadi, T., & Sahebkar, A. (2021). Cardiac Injury in COVID-19: A Systematic Review. In P. C. Guest (Ed.), Clinical, Biological and Molecular Aspects of COVID-19 (325-333). Cham: Springer. https://doi.org/10.1007/978-3-030-59261-5_29

© 2021, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG. Coronavirus 2019 (COVID-19) is responsible for the current pandemic which has already resulted in considerable mortality worldwide. Th... Read More about Cardiac Injury in COVID-19: A Systematic Review.

Therapeutics for type-2 diabetes mellitus: a glance at the recent inclusions and novel agents under development for use in clinical practice (2021)
Journal Article
Shah, N., Abdalla, M. A., Deshmukh, H., & Sathyapalan, T. (2021). Therapeutics for type-2 diabetes mellitus: a glance at the recent inclusions and novel agents under development for use in clinical practice. Therapeutic Advances in Endocrinology and Metabolism, 12, https://doi.org/10.1177/20420188211042145

Diabetes mellitus (DM) is a chronic, progressive, and multifaceted illness resulting in significant physical and psychological detriment to patients. As of 2019, 463 million people are estimated to be living with DM worldwide, out of which 90% have t... Read More about Therapeutics for type-2 diabetes mellitus: a glance at the recent inclusions and novel agents under development for use in clinical practice.

Natural Insulin Sensitizers for the Management of Diabetes Mellitus: A Review of Possible Molecular Mechanisms (2021)
Book Chapter
Yaribeygi, H., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2021). Natural Insulin Sensitizers for the Management of Diabetes Mellitus: A Review of Possible Molecular Mechanisms. In A. Sahebkar, & T. Sathyapalan (Eds.), Natural Products and Human Diseases (401-410). Cham: Springer. https://doi.org/10.1007/978-3-030-73234-9_26

Diabetes mellitus is a growing health challenge globally which is increasing in epidemic proportion. Naturally occurring pharmacological agents are more likely to provide beneficial therapeutic effects without undesirable side effects compared to the... Read More about Natural Insulin Sensitizers for the Management of Diabetes Mellitus: A Review of Possible Molecular Mechanisms.

siRNA Therapeutics: Future Promise for Neurodegenerative Diseases (2021)
Journal Article
Amiri, A., Barreto, G., Sathyapalan, T., & Sahebkar, A. (2021). siRNA Therapeutics: Future Promise for Neurodegenerative Diseases. Current Neuropharmacology, 19(11), 1896-1911. https://doi.org/10.2174/1570159X19666210402104054

Neurodegenerative diseases (ND), as a group of central nervous system (CNS) disorders, are among the most prominent medical problems of the 21st century. They are often associated with considerable disability, motor dysfunction and dementia and are m... Read More about siRNA Therapeutics: Future Promise for Neurodegenerative Diseases.

Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial (2020)
Journal Article
Yiasemidou, M., Mushtaq, F., Basheer, M., Galli, R., Panagiotou, D., Stock, S., …Miskovic, D. (2021). Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial. BJS Open, 5(2), Article zraa004. https://doi.org/10.1093/bjsopen/zraa004

Background It was hypothesized that preparing for a surgical procedure, taking into account individual patient characteristics, may facilitate the procedure and improve surgical quality. The aim of this study was to compare different case-specific,... Read More about Patient-specific mental rehearsal with three-dimensional models before low anterior resection: randomized clinical trial.