The Curious Case of Cough in Interstitial Lung Diseases
(2022)
Journal Article
van Manen, M. J., & Hart, S. P. (2022). The Curious Case of Cough in Interstitial Lung Diseases. Chest, 162(3), 501-502. https://doi.org/10.1016/j.chest.2022.04.139
All Outputs (766)
Inflammatory Markers in Non-Obese Women with Polycystic Ovary Syndrome Are Not Elevated and Show No Correlation with Vitamin D Metabolites (2022)
Journal Article
Moin, A. S. M., Sathyapalan, T., Atkin, S. L., & Butler, A. E. (2022). Inflammatory Markers in Non-Obese Women with Polycystic Ovary Syndrome Are Not Elevated and Show No Correlation with Vitamin D Metabolites. Nutrients, 14(17), Article 3540. https://doi.org/10.3390/nu14173540INTRODUCTION: Chronic low-grade inflammation is a characteristic of women with polycystic ovary syndrome (PCOS), although this may be obesity-driven rather than an intrinsic facet of PCOS; furthermore, vitamin D deficiency, another common feature of... Read More about Inflammatory Markers in Non-Obese Women with Polycystic Ovary Syndrome Are Not Elevated and Show No Correlation with Vitamin D Metabolites.
Time in range following flash glucose monitoring: Relationship with glycaemic control, diabetes-related distress and resource utilisation in the Association of British Clinical Diabetologists national audit (2022)
Journal Article
Deshmukh, H., Wilmot, E., Pieri, B., Choudhary, P., Shah, N., Gregory, R., …Sathyapalan, T. (2022). Time in range following flash glucose monitoring: Relationship with glycaemic control, diabetes-related distress and resource utilisation in the Association of British Clinical Diabetologists national audit. Diabetic medicine, Article e14942. https://doi.org/10.1111/dme.14942Aims: The aim of this study was to understand the relationship between time in range (TIR) achieved using the isCGM with changes in glycaemic control, diabetes-related distress (DRD) and resource utilisation in people living with diabetes. Methods: C... Read More about Time in range following flash glucose monitoring: Relationship with glycaemic control, diabetes-related distress and resource utilisation in the Association of British Clinical Diabetologists national audit.
Spore exines increase vitamin D clinical bioavailability by mucoadhesion and bile triggered release (2022)
Journal Article
Diego-Taboada, A., Sathyapalan, T., Courts, F., Lorch, M., Almutairi, F., Burke, B. P., …Mackenzie, G. (2022). Spore exines increase vitamin D clinical bioavailability by mucoadhesion and bile triggered release. Journal of controlled release : official journal of the Controlled Release Society, 350, 244-255. https://doi.org/10.1016/j.jconrel.2022.08.017Sporopollenin exine capsules (SpECs) are microcapsules derived from the outer shells (exines) of plant spore and pollen grains. This work reports the first clinical study on healthy volunteers to show enhanced bioavailability of vitamin D encapsulate... Read More about Spore exines increase vitamin D clinical bioavailability by mucoadhesion and bile triggered release.
Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings (2022)
Journal Article
Hutchinson, A., Allgar, V., Cohen, J., Currow, D. C., Griffin, S., Hart, S., …Johnson, M. J. (2022). Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings. ERJ Open Research, 8(4), Article 00257-2022. https://doi.org/10.1183/23120541.00257-2022Introduction: One-fifth of emergency department presentations by ambulance are due to acute-on-chronic breathlessness. We explored the feasibility of an evaluation-phase, cluster randomised controlled trial (cRCT) of the effectiveness and cost-effect... Read More about Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings.
Impaired awareness of hypoglycaemia: Prevalence and associated factors before and after FreeStyle Libre use in the Association of British Clinical Diabetologists audit (2022)
Journal Article
Pieri, B., Deshmukh, H., Wilmot, E. G., Choudhary, P., Shah, N., Gregory, R., …Sathyapalan, T. (2023). Impaired awareness of hypoglycaemia: Prevalence and associated factors before and after FreeStyle Libre use in the Association of British Clinical Diabetologists audit. Diabetes, Obesity and Metabolism, 25(1), 302-305. https://doi.org/10.1111/dom.14841
MiRNA and associated inflammatory changes from baseline to hypoglycemia in type 2 diabetes (2022)
Journal Article
Ramanjaneya, M., Priyanka, R., Bensila, M., Jerobin, J., Pawar, K., Sathyapalan, T., …Butler, A. E. (2022). MiRNA and associated inflammatory changes from baseline to hypoglycemia in type 2 diabetes. Frontiers in endocrinology, 13, Article 917041. https://doi.org/10.3389/fendo.2022.917041Objective: Hypoglycemia in type 2 diabetes (T2D) increases morbidity and mortality but the underlying physiological response is still not fully understood, though physiological changes are still apparent 24 hours after the event. Small noncoding micr... Read More about MiRNA and associated inflammatory changes from baseline to hypoglycemia in type 2 diabetes.
Diagnostic accuracy of telemedicine for detection of surgical site infection: a systematic review and meta-analysis (2022)
Journal Article
Lathan, R., Sidapra, M., Yiasemidou, M., Long, J., Totty, J., Smith, G., & Chetter, I. (2022). Diagnostic accuracy of telemedicine for detection of surgical site infection: a systematic review and meta-analysis. npj Digital Medicine, 5(1), Article 108. https://doi.org/10.1038/s41746-022-00655-0The Sars-CoV-2 pandemic catalysed integration of telemedicine worldwide. This systematic review assesses it’s accuracy for diagnosis of Surgical Site Infection (SSI). Databases were searched for telemedicine and wound infection studies. All types of... Read More about Diagnostic accuracy of telemedicine for detection of surgical site infection: a systematic review and meta-analysis.
Ethnic disparities in people accessing FreeStyle Libre in the UK: insights from the Association of British Clinical Diabetologists audit (2022)
Journal Article
Deshmukh, H., Adeleke, K. A., Wilmot, E., Shah, N., Patmore, J., Walton, C., Ryder, R. E. J., & Sathyapalan, T. (2022). Ethnic disparities in people accessing FreeStyle Libre in the UK: insights from the Association of British Clinical Diabetologists audit. Future Healthcare Journal, 9(Suppl 2), 11-11. https://doi.org/10.7861/fhj.9-2-s11
The Translational Role of miRNA in Polycystic Ovary Syndrome: From Bench to Bedside—A Systematic Literature Review (2022)
Journal Article
Vitale, S. G., Fulghesu, A. M., Mikuš, M., Watrowski, R., D’Alterio, M. N., Lin, L. T., …Angioni, S. (2022). The Translational Role of miRNA in Polycystic Ovary Syndrome: From Bench to Bedside—A Systematic Literature Review. Biomedicines, 10(8), Article 1816. https://doi.org/10.3390/biomedicines10081816MicroRNAs (miRNAs) are small, non-coding RNAs that are essential for the regulation of post-transcriptional gene expression during tissue development and differentiation. They are involved in the regulation of manifold metabolic and hormonal processe... Read More about The Translational Role of miRNA in Polycystic Ovary Syndrome: From Bench to Bedside—A Systematic Literature Review.
Improvements in Objective and Subjective Measures of Chronic Cough with Gefapixant: A Pooled Phase 3 Efficacy Analysis of Predefined Subgroups (2022)
Journal Article
Smith, J. A., Birring, S. S., Dicpinigaitis, P. V., McGarvey, L. P., Morice, A. H., Pavord, I. D., …Muccino, D. (2022). Improvements in Objective and Subjective Measures of Chronic Cough with Gefapixant: A Pooled Phase 3 Efficacy Analysis of Predefined Subgroups. Lung, 200(4), 423-429. https://doi.org/10.1007/s00408-022-00553-yIntroduction: In phase 3 trials (COUGH-1/COUGH-2), gefapixant 45 mg twice daily significantly reduced 24-h cough frequency vs placebo in refractory or unexplained chronic cough (RCC or UCC). Methods: Here, the efficacy of gefapixant 45 mg vs placebo... Read More about Improvements in Objective and Subjective Measures of Chronic Cough with Gefapixant: A Pooled Phase 3 Efficacy Analysis of Predefined Subgroups.
Therapeutic effects of statins on osteoarthritis: A review (2022)
Journal Article
Saberianpour, S., Abolbashari, S., Modaghegh, M. H., Karimian, M. S., Eid, A. H., Sathyapalan, T., & Sahebkar, A. (2022). Therapeutic effects of statins on osteoarthritis: A review. Journal of Cellular Biochemistry, 123(8), 1285-1297. https://doi.org/10.1002/jcb.30309Osteoarthritis (OA) is a progressive joint disease. The etiology of OA is considered to be multifactorial. Currently, there is no definitive treatment for OA, and the existing treatments are not very effective. Hypercholesterolemia is considered a no... Read More about Therapeutic effects of statins on osteoarthritis: A review.
Inoperable malignant bowel obstruction: palliative interventions outcomes-mixed-methods systematic review (2022)
Journal Article
Patterson, M., Greenley, S., Ma, Y., Bullock, A., Curry, J., Smithson, J., …Johnson, M. J. (2022). Inoperable malignant bowel obstruction: palliative interventions outcomes-mixed-methods systematic review. BMJ supportive & palliative care, Article 003492. https://doi.org/10.1136/bmjspcare-2021-003492Background: Parenteral nutrition (PN) and palliative venting gastrostomies (PVG) are two interventions used clinically to manage inoperable malignant bowel obstruction (MBO); however, little is known about their role in clinical and quality-of-life o... Read More about Inoperable malignant bowel obstruction: palliative interventions outcomes-mixed-methods systematic review.
Research priorities in diabetic foot disease (2022)
Journal Article
Collings, R., Shalhoub, J., Atkin, L., Game, F., Hitchman, L., Long, J., …Russell, D. (2022). Research priorities in diabetic foot disease. Journal of Vascular Societies Great Britain and Ireland, 1(4), 124-129. https://doi.org/10.54522/jvsgbi.2022.031Introduction: Diabetic foot disease is a life-changing event for patients and is associated with high burdens to society in terms of cost, mortality and morbidity. The Vascular Society Diabetic Foot Specialist Interest Group (VSDFSIG), in association... Read More about Research priorities in diabetic foot disease.
The Effect of Probiotic and Synbiotic Consumption on the Most Prevalent Chemotherapy-related Complications: A Systematic Review of Current Literature (2022)
Journal Article
Arab, A., Karimi, E., Bagherniya, M., Sathyapalan, T., & Sahebkar, A. (2022). The Effect of Probiotic and Synbiotic Consumption on the Most Prevalent Chemotherapy-related Complications: A Systematic Review of Current Literature. Current medicinal chemistry, 29(33), 5462-5473. https://doi.org/10.2174/0929867329666220415114343Background: To date, many investigations have employed pro-/synbiotic to examine their effects on chemotherapy-related side effects; nevertheless, their findings are inconclu-sive. To address this issue, we carried out a systematic review to explore... Read More about The Effect of Probiotic and Synbiotic Consumption on the Most Prevalent Chemotherapy-related Complications: A Systematic Review of Current Literature.
A survey of surgical site infection prevention practice in UK vascular surgery (2022)
Journal Article
lathan, R., yiasemidou, M., long, J., Mohamed, A., hitchman, L., smith, G., & Chetter, I. (2022). A survey of surgical site infection prevention practice in UK vascular surgery. Journal of Vascular Societies Great Britain and Ireland, 1(4), 117-123. https://doi.org/10.54522/jvsgbi.2022.030Background: Surgical site infections (SSI) have a significant impact on morbidity and mortality within vascular surgery. Despite the publication of several guidelines, there is a lack of consensus regarding the most effective perioperative practice t... Read More about A survey of surgical site infection prevention practice in UK vascular surgery.
Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial (2022)
Journal Article
Birkett, S., Sinclair, J., Seed, S., Pymer, S., Caldow, E., Ingle, L., Harwood, A., & Egun, A. (2022). Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial. Therapeutic Advances in Cardiovascular Disease, 16, https://doi.org/10.1177/17539447221108817Background: Peripheral artery disease affects over 236 million people globally and the classic symptom is intermittent claudication (IC) which is associated with reduction in physical activity. The evidence that supervised exercise programmes (SEPs)... Read More about Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial.
Phytochemicals as Modulators of Paraoxonase‐1 in Health and Diseases (2022)
Journal Article
Arab, Z. N., Khayatan, D., Razavi, S. M., Zare, K., Kheradkhah, E., Momtaz, S., …Sahebkar, A. (2022). Phytochemicals as Modulators of Paraoxonase‐1 in Health and Diseases. Antioxidants, 11(7), Article 1273. https://doi.org/10.3390/antiox11071273Chronic diseases such as cardiovascular disease (CVD), atherosclerosis, chronic liver disease, and neurodegenerative diseases are major causes of mortality. These diseases have gained much attention due to their complications, and therefore novel app... Read More about Phytochemicals as Modulators of Paraoxonase‐1 in Health and Diseases.
Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure (2022)
Journal Article
Kazmi, S., Kambhampati, C., Cleland, J., Cuthbert, J., Kazmi, K. S., Pellicori, P., …Clark, A. L. (2022). Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure. ESC Heart Failure, https://doi.org/10.1002/ehf2.14028Aims: Risk changes with the progression of disease and the impact of treatment. We developed a dynamic risk stratification Markov chain model using artificial intelligence in patients with chronic heart failure (CHF). Methods and results: We describe... Read More about Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure.
The impact of COVID19 on the presentation, diagnosis and management of cutaneous melanoma and squamous cell carcinoma in a single tertiary referral centre (2022)
Journal Article
McClean, A., Matteucci, P., & Totty, J. (in press). The impact of COVID19 on the presentation, diagnosis and management of cutaneous melanoma and squamous cell carcinoma in a single tertiary referral centre. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, https://doi.org/10.1016/j.bjps.2022.06.062The SARS-CoV-2 pandemic has had a substantial impact on the provision of surgical services worldwide1. In the United Kingdom, staff redeployment and reduced staffing due to infection and self-isolation has reduced the availability of clinic slots and... Read More about The impact of COVID19 on the presentation, diagnosis and management of cutaneous melanoma and squamous cell carcinoma in a single tertiary referral centre.