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A systematic review of muscle morphology and function in intermittent claudication (2017)
Journal Article
Harwood, A. E., King, S., Totty, J., Smith, G. E., Vanicek, N., & Chetter, I. C. (2017). A systematic review of muscle morphology and function in intermittent claudication. Journal of vascular surgery, 66(4), 1241-1257. https://doi.org/10.1016/j.jvs.2017.05.106

Objective Intermittent claudication (IC) is frequently associated with deterioration in walking capacity and physical function, and it can often result in an impairment in balance. Whereas supervised exercise is recommended by the National Institute... Read More about A systematic review of muscle morphology and function in intermittent claudication.

MicroRNA-31 regulates chemosensitivity in malignant pleural mesothelioma (2017)
Journal Article
Moody, H. L., Lind, M. J., & Maher, S. G. (2017). MicroRNA-31 regulates chemosensitivity in malignant pleural mesothelioma. Molecular Therapy - Nucleic Acids, 8(15 September 2017), 317-329. https://doi.org/10.1016/j.omtn.2017.07.001

Malignant pleural mesothelioma (MPM) is associated with an extremely poor prognosis, and most patients initially are or rapidly become unresponsive to platinum-based chemotherapy. MicroRNA-31 (miR-31) is encoded on a genomic fragile site, 9p21.3, whi... Read More about MicroRNA-31 regulates chemosensitivity in malignant pleural mesothelioma.

Theobromine for the treatment of persistent cough: A randomised, multicentre, double-blind, placebo-controlled clinical trial (2017)
Journal Article
Morice, A. H., McGarvey, L., Pavord, I. D., Higgins, B., Chung, K. F., & Birring, S. S. (2017). Theobromine for the treatment of persistent cough: A randomised, multicentre, double-blind, placebo-controlled clinical trial. Journal of thoracic disease, 9(7), 1864-1872. https://doi.org/10.21037/jtd.2017.06.18

© Journal of Thoracic Disease. Background: To investigate the effect of BC1036 on health-related quality of life (QOL) in subjects with persistent cough. The secondary objective was to investigate the effect of BC1036 on subjective cough severity. Me... Read More about Theobromine for the treatment of persistent cough: A randomised, multicentre, double-blind, placebo-controlled clinical trial.

The emerging role of the eosinophil and its measurement in chronic cough (2017)
Journal Article
Sadeghi, M. H., & Morice, A. H. (2017). The emerging role of the eosinophil and its measurement in chronic cough. Open Respiratory Medicine Journal, 11, 17-30. https://doi.org/10.2174/1874306401711010017

© 2017 Sadeghi & Morice. Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastrooesophageal reflux disease (GORD), and upper airways disease, the inflammatory mechanisms underlying these condi... Read More about The emerging role of the eosinophil and its measurement in chronic cough.

Deoxynivalenol biomarkers in the urine of UK vegetarians (2017)
Journal Article
Wells, L., Hardie, L., Williams, C., White, K., Liu, Y., De Santis, B., Debegnach, F., Moretti, G., Greetham, S., Brera, C., Papageorgiou, M., Thatcher, N. J., Rigby, A., Atkin, S. L., & Sathyapalan, T. (2017). Deoxynivalenol biomarkers in the urine of UK vegetarians. Toxins, 9(7), 196. https://doi.org/10.3390/toxins9070196

Deoxynivalenol (DON) is produced by Fusarium graminearum and is one of the most commonly occurring trichothecenes. Vegetarians are alleged to be a high-risk group for DON exposure due to high intakes of cereals susceptible to the growth of the mycoto... Read More about Deoxynivalenol biomarkers in the urine of UK vegetarians.

Salivary testosterone measurement in women with and without polycystic ovary syndrome (2017)
Journal Article
Sathyapalan, T., Al-Qaissi, A., Kilpatrick, E. S., Dargham, S. R., Adaway, J., Keevil, B., & Atkin, S. L. (2017). Salivary testosterone measurement in women with and without polycystic ovary syndrome. Scientific reports, 7(1), Article ARTN 3589. https://doi.org/10.1038/s41598-017-03945-w

Clinical and/or biochemical hyperandrogenism is one of the diagnostic criteria for PCOS. An evaluation of the role of salivary testosterone (salT) and androstenedione (salA) for the diagnosis of PCOS was undertaken in a cross sectional study involvin... Read More about Salivary testosterone measurement in women with and without polycystic ovary syndrome.

Androsterone glucuronide to dehydroepiandrosterone sulphate ratio is discriminatory for obese Caucasian women with polycystic ovary syndrome (2017)
Journal Article
Cho, L. W., Sathyapalan, T., Kilpatrick, E. S., Keevil, B. G., Miller, A. G., Coady, A. M., Ahmed, L., & Atkin, S. L. (2017). Androsterone glucuronide to dehydroepiandrosterone sulphate ratio is discriminatory for obese Caucasian women with polycystic ovary syndrome. BMC Endocrine Disorders, 17(1), Article 26. https://doi.org/10.1186/s12902-017-0177-3

BACKGROUND: Androsterone glucuronide (ADTG) concentrations have been suggested as a marker of the effects of androgens at the target tissue level. As the mechanism for hyperandrogenemia in obese and nonobese polycystic ovary syndrome (PCOS) may diffe... Read More about Androsterone glucuronide to dehydroepiandrosterone sulphate ratio is discriminatory for obese Caucasian women with polycystic ovary syndrome.

Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery (2017)
Journal Article
Carradice, D., Chetter, I. C., Totty, J. P., Wallace, T., Bua, N., Pan, D., & Smith, G. E. (2017). Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery. Annals of vascular surgery, 44, 387-392. https://doi.org/10.1016/j.avsg.2017.03.198

© 2017 Elsevier Inc. Background Dressings coated with dialkylcarbamoyl chloride (DACC) are highly hydrophobic and irreversibly bind multiple types of bacteria, trapping them in the dressing and reducing the number of organisms at the wound surface. W... Read More about Dialkylcarbamoyl Chloride Dressings in the Prevention of Surgical Site Infections after Nonimplant Vascular Surgery.

Cough hypersensitivity syndrome: A few more steps forward (2017)
Journal Article
Song, W. J., & Morice, A. H. (2017). Cough hypersensitivity syndrome: A few more steps forward. Allergy Asthma and Immunology Research, 9(5), 394-402. https://doi.org/10.4168/aair.2017.9.5.394

© The Korean Academy of Asthma, Allergy and Clinical Immunology. Cough reflex is a vital protective mechanism against aspiration, but when dysregulated, it can become hypersensitive. In fact, chronic cough is a significant medical problem with a high... Read More about Cough hypersensitivity syndrome: A few more steps forward.

Quality of life in patients with intermittent claudication (2017)
Journal Article
Harwood, A. E., Totty, J. P., Broadbent, E., Smith, G. E., & Chetter, I. C. (2017). Quality of life in patients with intermittent claudication. Gefässchirurgie, 22(3), 159-164. https://doi.org/10.1007/s00772-017-0269-4

© 2017, The Author(s). Background: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients. The QoL is therefore often regarded... Read More about Quality of life in patients with intermittent claudication.

Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study (2017)
Journal Article
Sathyapalan, T., Javed, Z., Rigby, A. S., Kilpatrick, E. S., & Atkin, S. L. (2017). Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study. Journal of the Endocrine Society, 1(5), 423-430. https://doi.org/10.1210/js.2016-1068

© 2017 Endocrine Society. Background: Soy protein with isoflavones appears to have an adverse effect on thyroid function, but it is not known whether it is the protein or isoflavone component that is deleterious. The effect of isoflavone-free soy on... Read More about Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study.

A new way to look at acute cough in the pharmacy (2017)
Journal Article
Morice, A. H. (2017). A new way to look at acute cough in the pharmacy. Pharmaceutical Journal, 9(4), https://doi.org/10.1211/CP.2017.20202484

© 2017 Royal Pharmaceutical Society. All rights reserved. Cough is the most common symptom for which people seek medical advice, and patients with cough frequently present to community pharmacy. Cough can be either acute or chronic. Acute cough, defi... Read More about A new way to look at acute cough in the pharmacy.

Point prevalence and epidemiological characteristics of chronic cough in the general adult population: The Korean National Health and Nutrition Examination Survey 2010-2012 (2017)
Journal Article
Kang, M. G., Song, W. J., Kim, H. J., Won, H. K., Sohn, K. H., Kang, S. Y., Jo, E. J., Kim, M. H., Kim, S. H., Kim, S. H., Park, H. W., Chang, Y. S., Lee, B. J., Morice, A. H., & Cho, S. H. (2017). Point prevalence and epidemiological characteristics of chronic cough in the general adult population: The Korean National Health and Nutrition Examination Survey 2010-2012. Medicine, 96(13), Article e6486. https://doi.org/10.1097/MD.0000000000006486

© 2017 the Author(s). Cough is frequently self-limiting, but may persist longer in certain individuals. Most of previous studies on the epidemiology of chronic cough have only measured period prevalence, and thus have afforded limited information on... Read More about Point prevalence and epidemiological characteristics of chronic cough in the general adult population: The Korean National Health and Nutrition Examination Survey 2010-2012.

Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation (2017)
Journal Article
Crooks, M. G., den Brinker, A., Hayman, Y., Williamson, J. D., Innes, A., Wright, C. E., Hill, P., & Morice, A. H. (2017). Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation. Lung, 195(3), 289-294. https://doi.org/10.1007/s00408-017-9996-2

Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases during acute exacerbations (AE-COPD), representing a possible metric of clinical deteriorat... Read More about Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation.

British Lung Foundation/United Kingdom primary immunodeficiency network consensus statement on the definition, diagnosis, and management of granulomatous-lymphocytic interstitial lung disease in common variable immunodeficiency disorders (2017)
Journal Article
Hurst, J. R., Verma, N., Lowe, D., Baxendale, H. E., Jolles, S., Kelleher, P., Longhurst, H. J., Patel, S. Y., Renzoni, E. A., Sander, C. R., Avery, G. R., Babar, J. L., Buckland, M. S., Burns, S., Egner, W., Gompels, M. M., Gordins, P., Haddock, J. A., Hart, S. P., Hayman, G. R., …Condliffe, A. M. (2017). British Lung Foundation/United Kingdom primary immunodeficiency network consensus statement on the definition, diagnosis, and management of granulomatous-lymphocytic interstitial lung disease in common variable immunodeficiency disorders. The journal of allergy and clinical immunology. In practice, 5(4), 938-945. https://doi.org/10.1016/j.jaip.2017.01.021

A proportion of people living with common variable immunodeficiency disorders develop granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a consensus statement on the definition, diagnosis, and management of GLILD. All UK... Read More about British Lung Foundation/United Kingdom primary immunodeficiency network consensus statement on the definition, diagnosis, and management of granulomatous-lymphocytic interstitial lung disease in common variable immunodeficiency disorders.

Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease (2017)
Presentation / Conference Contribution
Mazari, F. A., Khan, J. A., Samuel, N., Smith, G., Carradice, D., McCollum, P., & Chetter, I. Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease

Background: To compare the long-term outcomes of angioplasty (PTA), supervised exercise (SEP) and combined treatment (PTA+SEP) in patients with intermittent claudication (IC) due to femoropopliteal disease. Methods: Patients recruited to PTA, SEP and... Read More about Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease.