All Outputs (701)

The Impact of Previous Surgery and Revisions on Outcome after Major Lower Limb Amputation (2013)
Journal Article
Souroullas, P., Barnes, R., Lane, R. A., & Chetter, I. (2014). The Impact of Previous Surgery and Revisions on Outcome after Major Lower Limb Amputation. Annals of vascular surgery, 28(5), 1166-1171. https://doi.org/10.1016/j.avsg.2013.10.017

IntroductionMorbidity and mortality after lower limb amputation (LLA) remain disappointingly high. This study aimed to assess the impact of previous ipsilateral vascular intervention on outcomes after major LLA.MethodsProspective data were collected... Read More about The Impact of Previous Surgery and Revisions on Outcome after Major Lower Limb Amputation.

Chong Acupuncture Meridian, An Ancient Chinese Description of the Vascular System? (2013)
Presentation / Conference Contribution
Shaw, V. (2013, December). Chong Acupuncture Meridian, An Ancient Chinese Description of the Vascular System?. Presented at Anatomical Society Winter Meeting 2013: Assessment Within Medical Education & Sense Organs, Newcastle upon Tyne, UK

The positioning of the acupuncture points in acupuncture is based upon a particular anatomical map known as the jıng luo經絡(meridian network system) which has no obvious correlate in modern anatomy. The generally accepted scholarly opinion is that t... Read More about Chong Acupuncture Meridian, An Ancient Chinese Description of the Vascular System?.

Glucagon-like peptide-1 analogue, liraglutide, improves liver fibrosis markers in obese women with polycystic ovary syndrome and nonalcoholic fatty liver disease (2013)
Journal Article
Kahal, H., Abouda, G., Rigby, A. S., Coady, A. M., Kilpatrick, E. S., & Atkin, S. L. (2014). Glucagon-like peptide-1 analogue, liraglutide, improves liver fibrosis markers in obese women with polycystic ovary syndrome and nonalcoholic fatty liver disease. Clinical Endocrinology, 81(4), 523-528. https://doi.org/10.1111/cen.12369

© 2013 John Wiley & Sons Ltd. Introduction: Nonalcoholic fatty liver disease (NAFLD) has been linked to polycystic ovary syndrome (PCOS) and carries an increased risk of liver cirrhosis. Procollagen type 3 amino-terminal peptide (PIIINP) is an inde... Read More about Glucagon-like peptide-1 analogue, liraglutide, improves liver fibrosis markers in obese women with polycystic ovary syndrome and nonalcoholic fatty liver disease.

Supervised exercise program improves aerobic fitness in patients awaiting abdominal aortic aneurysm repair (2013)
Journal Article
Barakat, H. M., Shahin, Y., Barnes, R., Gohil, R., Souroullas, P., Khan, J., McCollum, P. T., & Chetter, I. C. (2014). Supervised exercise program improves aerobic fitness in patients awaiting abdominal aortic aneurysm repair. Annals of vascular surgery, 28(1), 74-79. https://doi.org/10.1016/j.avsg.2013.09.001

Background
Aerobic fitness is an important predictor of postoperative outcome in major surgery. In this study, we assess the effects of a period of preoperative exercise on aerobic fitness as measured by cardiopulmonary exercise testing (CPET) in pa... Read More about Supervised exercise program improves aerobic fitness in patients awaiting abdominal aortic aneurysm repair.

Computerized dynamic posturography for postural control assessment in patients with intermittent claudication. (2013)
Journal Article
Vanicek, N., King, S. A., Gohil, R., Chetter, I. C., & Coughlin, P. A. (2013). Computerized dynamic posturography for postural control assessment in patients with intermittent claudication. Journal of Visualized Experiments, Article e51077. https://doi.org/10.3791/51077

Computerized dynamic posturography with the EquiTest is an objective technique for measuring postural strategies under challenging static and dynamic conditions. As part of a diagnostic assessment, the early detection of postural deficits is importan... Read More about Computerized dynamic posturography for postural control assessment in patients with intermittent claudication..

Meta-analysis of angiotensin converting enzyme inhibitors effect on walking ability and ankle brachial pressure index in patients with intermittent claudication (2013)
Journal Article
Shahin, Y., Barnes, R., Barakat, H., & Chetter, I. C. (2013). Meta-analysis of angiotensin converting enzyme inhibitors effect on walking ability and ankle brachial pressure index in patients with intermittent claudication. Atherosclerosis, 231(2), 283-290. https://doi.org/10.1016/j.atherosclerosis.2013.09.037

Objective
The aim of this meta-analysis was to investigate the effect of angiotensin converting enzyme (ACE) inhibitors on maximum walking distance (MWD), pain-free walking distance (PFWD) and ankle brachial pressure index (ABPI) in patients with in... Read More about Meta-analysis of angiotensin converting enzyme inhibitors effect on walking ability and ankle brachial pressure index in patients with intermittent claudication.

A comparison of physical activity correlates across breast, prostate and colorectal cancer survivors in Nova Scotia, Canada (2013)
Journal Article
Forbes, C. C., Blanchard, C. M., Mummery, W. K., & Courneya, K. S. (2014). A comparison of physical activity correlates across breast, prostate and colorectal cancer survivors in Nova Scotia, Canada. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(4), 891-903. https://doi.org/10.1007/s00520-013-2045-7

Purpose: The purpose of this study was to compare the medical, demographic and social cognitive correlates of physical activity (PA) in breast (BCS), prostate (PCS) and colorectal (CRCS) cancer survivors. Methods: A stratified random sample of 2062 B... Read More about A comparison of physical activity correlates across breast, prostate and colorectal cancer survivors in Nova Scotia, Canada.

Insulin resistance and cardiovascular risk marker evaluation in morbid obesity 12 months after bariatric surgery compared to weight-matched controls (2013)
Journal Article
Dawson, A. J., Sathyapalan, T., Sedman, P., Ajjan, R., Kilpatrick, E. S., & Atkin, S. L. (2014). Insulin resistance and cardiovascular risk marker evaluation in morbid obesity 12 months after bariatric surgery compared to weight-matched controls. Obesity Surgery, 24(3), 349-358. https://doi.org/10.1007/s11695-013-1100-2

Background Insulin resistance (IR) after bariatric surgery is significantly lower than controls matched for bodymass index (BMI) and is indistinguishable from lean subjects however it is not known if this is the same for associated cardiovascular ris... Read More about Insulin resistance and cardiovascular risk marker evaluation in morbid obesity 12 months after bariatric surgery compared to weight-matched controls.

Outcomes after open repair of ruptured abdominal aortic aneurysms in octogenarians: a 20-year, single-center experience (2013)
Journal Article
Barakat, H. M., Shahin, Y., Barnes, R., Chetter, I., & McCollum, P. (2014). Outcomes after open repair of ruptured abdominal aortic aneurysms in octogenarians: a 20-year, single-center experience. Annals of vascular surgery, 28(1), 80-86. https://doi.org/10.1016/j.avsg.2013.07.006

Background
The purpose of this study was to evaluate morbidity, mortality, and survival in octogenarians undergoing open repair of ruptured abdominal aortic aneurysms (RAAAs) in comparison to younger patients.MethodsThis investigation was a retrospe... Read More about Outcomes after open repair of ruptured abdominal aortic aneurysms in octogenarians: a 20-year, single-center experience.

Neural responses to facial expressions support the role of the amygdala in processing threat (2013)
Journal Article
Mattavelli, G., Sormaz, M., Flack, T., Asghar, A. U., Fan, S., Frey, J., Manssuer, L., Usten, D., Young, A. W., & Andrews, T. J. (2014). Neural responses to facial expressions support the role of the amygdala in processing threat. Social Cognitive and Affective Neuroscience, 9(11), 1684-1689. https://doi.org/10.1093/scan/nst162

© The Author (2013). Published by Oxford University Press. The amygdala is known to play an important role in the response to facial expressions that convey fear. However, it remains unclear whether the amygdala's response to fear reflects its role i... Read More about Neural responses to facial expressions support the role of the amygdala in processing threat.

Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial (2013)
Journal Article
Courneya, K. S., McKenzie, D. C., Mackey, J. R., Gelmon, K., Friedenreich, C. M., Yasui, Y., Reid, R. D., Cook, D., Jespersen, D., Proulx, C., Dolan, L. B., Forbes, C. C., Wooding, E., Trinh, L., & Segal, R. J. (2013). Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial. JNCI: Journal of the National Cancer Institute, 105(23), 1821-1832. https://doi.org/10.1093/jnci/djt297

Background
Exercise improves physical functioning and symptom management during breast cancer chemotherapy, but the effects of different doses and types of exercise are unknown.

Methods
A multicenter trial in Canada randomized 301 breast cancer pati... Read More about Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial.

Workshop - Developing Clinical Reasoning Skills in Modern Undergraduate Medical Curricula (2013)
Presentation / Conference Contribution
Hammond, A., & Henderson, J. (2013, September). Workshop - Developing Clinical Reasoning Skills in Modern Undergraduate Medical Curricula. Presented at 8th HYMS Education Conference, Bishop Burton, East Yorkshire

Objectives:
Following the workshop participants will be able to
* Recognise opportunities to strengthen the teaching of clinical reasoning within their environment
* Evaluate students’ individual clinical reasoning learning needs
* Discuss curre... Read More about Workshop - Developing Clinical Reasoning Skills in Modern Undergraduate Medical Curricula.

Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen (2013)
Journal Article
Kashuba, E., Eagle, G. L., Bailey, J., Evans, P., Welham, K. J., Allsup, D., & Cawkwell, L. (2013). Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen. Journal of Proteomics, 91, 478-485. https://doi.org/10.1016/j.jprot.2013.08.002

CLL is an incurable disease with variable prognosis. The hyper reactivity of the B-cell receptor (BCR) to unknown antigen ligation plays a pivotal role in CLL-cell survival. We aimed to investigate the BCR signalling pathway using proteomics to ident... Read More about Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen.

Patient satisfaction with participation in a randomized exercise trial: Effects of randomization and a usual care posttrial exercise program (2013)
Journal Article
Courneya, K. S., Forbes, C. C., Trinh, L., Sellar, C. M., Friedenreich, C. M., & Reiman, T. (2013). Patient satisfaction with participation in a randomized exercise trial: Effects of randomization and a usual care posttrial exercise program. Clinical Trials, 10(6), 959-966. https://doi.org/10.1177/1740774513495985

Background
Participation in an exercise trial is a major commitment for cancer survivors, but few exercise trials have evaluated patient satisfaction with trial participation.

Purpose
To examine patient satisfaction with participation in the Healthy... Read More about Patient satisfaction with participation in a randomized exercise trial: Effects of randomization and a usual care posttrial exercise program.

Workshop: Helping undergraduate medical students to improve their clinical reasoning in the direct patient encounter - skills for tutors (2013)
Presentation / Conference Contribution
Hammond, A., & Henderson, J. (2013, July). Workshop: Helping undergraduate medical students to improve their clinical reasoning in the direct patient encounter - skills for tutors. Presented at Association for the Study of Medical Education Annual Scientific Meeting: Changes in healthcare delivery and the effects on medical education, Edinburgh

Workshop Description:
This workshop demonstrates how clinical consultations can be used in a structured way to facilitate student understanding of their own clinical reasoning. Participants will actively explore, analyse and practise some of the sk... Read More about Workshop: Helping undergraduate medical students to improve their clinical reasoning in the direct patient encounter - skills for tutors.

Increased frequency and suppressive activity of CD127low/- regulatory T cells in the peripheral circulation of patients with head and neck squamous cell carcinoma are associated with advanced stage and nodal involvement (2013)
Journal Article
Drennan, S., Stafford, N. D., Greenman, J., & Green, V. (2013). Increased frequency and suppressive activity of CD127low/- regulatory T cells in the peripheral circulation of patients with head and neck squamous cell carcinoma are associated with advanced stage and nodal involvement. Immunology, 140(3), 335-343. https://doi.org/10.1111/imm.12144

The presence of regulatory T (Treg) cells is thought to be an important mechanism by which head and neck squamous cell carcinoma (HNSCC) successfully evades the immune system. Using multicolour flow cytometry, the frequency and functional capacity of... Read More about Increased frequency and suppressive activity of CD127low/- regulatory T cells in the peripheral circulation of patients with head and neck squamous cell carcinoma are associated with advanced stage and nodal involvement.

Glycemic Control in the 12 Months following a Change to SI Hemoglobin A1c Reporting Units (2013)
Journal Article
Rigby, A., Atkin, S., Barth, J. H., & Kilpatrick, E. (2013). Glycemic Control in the 12 Months following a Change to SI Hemoglobin A1c Reporting Units. Clinical Chemistry, 59(10), 1457-1460. https://doi.org/10.1373/clinchem.2013.206334

BACKGROUND Many countries have implemented, or are considering, a change in hemoglobin A1c (Hb A1c) units from traditional percentage values [Diabetes Control and Complications Trial (DCCT)] to the new Système International d'Unités (SI) unit in mill... Read More about Glycemic Control in the 12 Months following a Change to SI Hemoglobin A1c Reporting Units.

Extension MRI is clinically useful in cervical myelopathy (2013)
Journal Article
Bartlett, R. J. V., Rigby, A. S., Joseph, J., Raman, A., Kunnacherry, A., & Hill, C. A. R. (2013). Extension MRI is clinically useful in cervical myelopathy. Neuroradiology, 55(9), 1081-1088. https://doi.org/10.1007/s00234-013-1208-z

Introduction: Cervical spine MRI with the neck in extension has been well described over the last 10 years, but its clinical value remains unknown. Methods: We performed extension imaging in 60 patients in whom the initial neutral study showed border... Read More about Extension MRI is clinically useful in cervical myelopathy.

P33. Optimising student experience: an innovative and integrated tutor support and development programme (2013)
Presentation / Conference Contribution
Hammond, A., & Henderson, J. (2013, May). P33. Optimising student experience: an innovative and integrated tutor support and development programme. Poster presented at Fifth International Clinical Skills Conference: Clinical Skills Education - Building Bridges between Simulation and Practice, Prato, Italy

Background The curriculum of the five year MBBS course at HYMS is integrated and student–centred with regular clinical skills sessions throughout the first two years. The clinical skills tutors are practising clinicians who deliver their teaching rol... Read More about P33. Optimising student experience: an innovative and integrated tutor support and development programme.

P06. Clinical Reasoning in Medicine: Developing Students' metacognitive skills (2013)
Presentation / Conference Contribution
Hammond, A., & Henderson, J. (2013, May). P06. Clinical Reasoning in Medicine: Developing Students' metacognitive skills. Poster presented at 5th International Clinical Skills Conference - Clinical Skills Education: Building Bridges between Simulation and Practice, Prato, Italy

This poster outlines the introduction of formal Clinical Reasoning Skills sessions - initially a Student Selected Component (SSC) - as compulsory sessions in the core second year curriculum.
Observations of 4th and 5th Year students’ performances i... Read More about P06. Clinical Reasoning in Medicine: Developing Students' metacognitive skills.