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All Outputs (677)

Abstract B001: Calcitonin receptor-like receptor agonists induce p44/42 MAPK phosphorylation in VEGF-A-stimulated human blood endothelial cells after bevacizumab treatment (2023)
Presentation / Conference Contribution
Morfitt, M. A., Greenman, J., Maraveyas, A., & Nikitenko, L. L. (2023). Abstract B001: Calcitonin receptor-like receptor agonists induce p44/42 MAPK phosphorylation in VEGF-A-stimulated human blood endothelial cells after bevacizumab treatment. Cancer Research, 83(16_Supplement), B001-B001. https://doi.org/10.1158/1538-7445.kidney23-b001

Introduction. Clear cell renal cell carcinoma (ccRCC) is a highly vascularized and clinically aggressive cancer. In the UK, there are around 9000 diagnoses and 3000 deaths annually. Targeted therapies that inhibit angiogenic regulators, such as bevac... Read More about Abstract B001: Calcitonin receptor-like receptor agonists induce p44/42 MAPK phosphorylation in VEGF-A-stimulated human blood endothelial cells after bevacizumab treatment.

Co-locating universal welfare advice in health settings for mothers and their families (2023)
Thesis
Reece, S. (2023). Co-locating universal welfare advice in health settings for mothers and their families. (Thesis). The University of Hull and the University of York. https://hull-repository.worktribe.com/output/4672312

Childhood deprivation is associated with poor health and social outcomes, limiting childhood development with long-lasting effects into adulthood. Welfare advice services improve financial security but access is often unequal for the most vulnerable.... Read More about Co-locating universal welfare advice in health settings for mothers and their families.

Biochemical characterisation of the interaction of the myosin light chain phosphatase with the regulatory subunits of protein kinase A in cells of the circulatory system (2023)
Thesis
Saldanha, P. A. C. B. D. S. Biochemical characterisation of the interaction of the myosin light chain phosphatase with the regulatory subunits of protein kinase A in cells of the circulatory system. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4790706

Regulation of actomyosin-driven contraction is important for numerous cardiovascular cell functions, including smooth muscle tone, endothelial cell permeability and platelet shape change and spreading. These processes are primarily regulated by the p... Read More about Biochemical characterisation of the interaction of the myosin light chain phosphatase with the regulatory subunits of protein kinase A in cells of the circulatory system.

Equipping teachers with the skills to assist students to develop their clinical reasoning and communication skills in patient consultations: an integrated approach (2023)
Presentation / Conference Contribution
Lillicrap, M., & Hammond, A. (2023, June). Equipping teachers with the skills to assist students to develop their clinical reasoning and communication skills in patient consultations: an integrated approach. Presented at Facilitator Development Day - University of Cambridge School of Medicine, Cambridge

Objectives:
* To consider the challenges teachers/tutors (experts) might face in helping medical students (novices) develop their clinical reasoning skills
* To develop awareness of the role of faculty development in helping teachers/tutors deve... Read More about Equipping teachers with the skills to assist students to develop their clinical reasoning and communication skills in patient consultations: an integrated approach.

Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. (2023)
Presentation / Conference Contribution
Nikitenko, L. L., Manolis, D., O'Brien, D. P., Adekeye, A., Kessler, B. M., Collins, C., Kramer, H., Chang, D., & Maraveyas, A. Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. Presented at The London Pancreas Workshop 2023, London, United Kingdom

In our EARLY DIAgnosis of PAncreatic Cancer (EARLY DIAPAC) study, we aim to analyse molecular changes or “signatures” associated with early stages of pancreatic carcinogenesis by using the combination of: (i) Label-Free Quantitative Proteomics (LFQP)... Read More about Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer..

Oral 13. Unconscious Bias Training for our Simulated Patients: Showcasing a new and innovative workshop (2023)
Presentation / Conference Contribution
Hammond, A., Whittaker, J., Frere, T., & Stockbridge, C. (2023, May). Oral 13. Unconscious Bias Training for our Simulated Patients: Showcasing a new and innovative workshop. Presented at 9th International Clinical Skills Conference, Prato, Italy

Oral Presentation objectives
1) To develop awareness of our innovative workshop delivered to our Simulated Patients to increase their understanding of unconscious biases, how these might impact their work as Simulated Patients in our teaching and as... Read More about Oral 13. Unconscious Bias Training for our Simulated Patients: Showcasing a new and innovative workshop.

Workshop 21. Faculty Development - Equipping clinical tutors with the skills to assist students to develop their clinical reasoning in patient consultations (2023)
Presentation / Conference Contribution
Hammond, A., Gay, S., Matthan, J., Cooper, N., & Singh, M. (2023, May). Workshop 21. Faculty Development - Equipping clinical tutors with the skills to assist students to develop their clinical reasoning in patient consultations. Presented at 9th International Clinical Skills Conference, Prato, Italy

Workshop Objectives
To consider the particular challenges for clinical tutors (experts) in helping medical students (novices) develop their clinical reasoning skills.
To develop awareness of innovative approaches to faculty development to help tuto... Read More about Workshop 21. Faculty Development - Equipping clinical tutors with the skills to assist students to develop their clinical reasoning in patient consultations.

Workshop 47. The Future of consulting: Impact of changing practice on our cognitive load as experts and educators & insights into the novice perspective (2023)
Presentation / Conference Contribution
Hammond, A., & Ambrose, L. (2023, May). Workshop 47. The Future of consulting: Impact of changing practice on our cognitive load as experts and educators & insights into the novice perspective. Presented at 9th International Clinical Skills Conference, Prato, Italy

Objectives
1) To consider current & future impact of remote consulting & the covid pandemic on our cognitive load as clinical reasoning ‘experts’
2) To consider & reflect on the insights this has provided us as clinicians & educators into the stud... Read More about Workshop 47. The Future of consulting: Impact of changing practice on our cognitive load as experts and educators & insights into the novice perspective.

Bringing fictional characters to life: reflections on co-creating a comic book with members of the public (2023)
Journal Article
Cairns, J. M., Roberts, H., Al-Khafaji, G., & Kwater, M. (2023). Bringing fictional characters to life: reflections on co-creating a comic book with members of the public. Research Involvement and Engagement, 9(1), Article 28. https://doi.org/10.1186/s40900-023-00437-2

There are growing calls for cancer screening to become more personalised by considering a range of risk factors, rather than a one-size-fits-all, age-based approach. The aim of this public involvement was to co-create a comic book about bowel cancer... Read More about Bringing fictional characters to life: reflections on co-creating a comic book with members of the public.

Improving asthma care through implementation of the SENTINEL programme: findings from the pilot site (2023)
Journal Article
Crooks, M. G., Crowther, L., Cummings, H., Cohen, J., Huang, C., Pitel, L., Pearson, M., Morice, A., Turgoose, J., Faruqi, S., Watt, M., Morris, T., & Xu, Y. (2023). Improving asthma care through implementation of the SENTINEL programme: findings from the pilot site. ERJ Open Research, 9(3), Article 00685-2022. https://doi.org/10.1183/23120541.00685-2022

Aim: Short-acting β2-agonist (SABA) overuse adversely impacts asthma-related outcomes and the environment. The SABA rEductioN Through ImplemeNting Hull asthma guidELines (SENTINEL) programme aims to reduce SABA overuse through supported implementatio... Read More about Improving asthma care through implementation of the SENTINEL programme: findings from the pilot site.

Addressing delays to treatment in patients with chronic limb-threatening ischaemia (2023)
Thesis
Birmpili, P. (2023). Addressing delays to treatment in patients with chronic limb-threatening ischaemia. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4371299

Patients with CLTI often face long delays from referral to the vascular surgery service and hospital admission to revascularisation, and there is limited evidence on the effect of these delays on patient outcomes. This thesis aims to identify factors... Read More about Addressing delays to treatment in patients with chronic limb-threatening ischaemia.

Keynote - Integration of communication and clinical reasoning skills: Evolution of a medical school curriculum and reflections of a GP (2023)
Presentation / Conference Contribution
Hammond, A. (2023, March). Keynote - Integration of communication and clinical reasoning skills: Evolution of a medical school curriculum and reflections of a GP. Presented at UK Conference for Clinical Communication in Undergraduate Medical Education: Developing the clinical communication curriculum, Manchester

Conference programme:
Anna will discuss the evolution of the HYMS curriculum (including the explicit teaching of clinical reasoning, and integration of the communication and clinical reasoning curricula) and reflect on the impact of her own practice... Read More about Keynote - Integration of communication and clinical reasoning skills: Evolution of a medical school curriculum and reflections of a GP.

Faculty Development: Equipping teachers with the skills to assist students to develop their clinical reasoning and communication skills in patient consultations - an integrated approach (2023)
Presentation / Conference Contribution
Hammond, A., & Lillicrap, M. (2023, March). Faculty Development: Equipping teachers with the skills to assist students to develop their clinical reasoning and communication skills in patient consultations - an integrated approach. Presented at UK Council of Clinical Communication National Conference, Manchester

This interactive and multimedia workshop will showcase an approach that integrates the teaching of communication and clinical reasoning skills, through observation and discussion.

· To consider the challenges teachers/tutors (experts) might face i... Read More about Faculty Development: Equipping teachers with the skills to assist students to develop their clinical reasoning and communication skills in patient consultations - an integrated approach.

Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol (2023)
Journal Article
Baldwin, Z.-A., Busby, S., Allsup, D., Cohen, J., & Bamidele, O. (2023). Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol. PLoS ONE, 18(3), Article e0282458. https://doi.org/10.1371/journal.pone.0282458

Introduction Haematological malignancies are a heterogenous group of blood and lymphatic cancers. Survivorship care is a similarly diverse term concerning patients’ health and wellbeing from diagnosis to end of life. Survivorship care for patients wi... Read More about Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol.

The effect of platelet releasate on oocytes has a detrimental impact on early mammalian embryos (2023)
Thesis
Martin, F. (2023). The effect of platelet releasate on oocytes has a detrimental impact on early mammalian embryos. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4430667

Background: Blood-derived products are a growing area of therapeutic treatments for a diverse range of conditions, including hair loss, scarring, muscle injury, wounds, arthritis, and symptoms related to the menopause. Platelet-rich plasma (PRP) is o... Read More about The effect of platelet releasate on oocytes has a detrimental impact on early mammalian embryos.

Authentic alignment : toward an Interpretative Phenomenological Analysis (IPA) informed model of the learning environment in health professions education (2023)
Thesis
Kirkness, K. (2023). Authentic alignment : toward an Interpretative Phenomenological Analysis (IPA) informed model of the learning environment in health professions education. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4407885

It is well established that the goals of education can only be achieved through the constructive alignment of instruction, learning and assessment. There is a gap in research interpreting the lived experiences of stakeholders within the UK learning e... Read More about Authentic alignment : toward an Interpretative Phenomenological Analysis (IPA) informed model of the learning environment in health professions education.

Competition Between Desired Competitive Result, Tolerable Homeostatic Disturbance, and Psychophysiological Interpretation Determines Pacing Strategy (2023)
Journal Article
Foster, C., de Koning, J. J., Hettinga, F. J., Barroso, R., Boullosa, D., Casado, A., Cortis, C., Fusco, A., Gregorich, H., Jaime, S., Jones, A. M., Malterer, K. R., Pettitt, R., Porcari, J. P., Pratt, C., Reinschmidt, P., Skiba, P., Splinter, A., St Clair Gibson, A., St Mary, J., …van Tunen, J. (2023). Competition Between Desired Competitive Result, Tolerable Homeostatic Disturbance, and Psychophysiological Interpretation Determines Pacing Strategy. International journal of sports physiology and performance : IJSPP, https://doi.org/10.1123/ijspp.2022-0171

Scientific interest in pacing goes back >100 years. Contemporary interest, both as a feature of athletic competition and as a window into understanding fatigue, goes back >30 years. Pacing represents the pattern of energy use designed to produce a co... Read More about Competition Between Desired Competitive Result, Tolerable Homeostatic Disturbance, and Psychophysiological Interpretation Determines Pacing Strategy.

The long-term impact of glucose monitoring with the FreeStyle Libre on glycaemic control and hypoglycaemia awareness in people with type1 diabetes: Insights from the Association of British Clinical Diabetologists national audit (2023)
Journal Article
Shah, N., Deshmukh, H., Wilmot, E. G., Patmore, J., Christian, P., Barnes, D. J., Walton, C., Ryder, R. E. J., & Sathyapalan, T. (2023). The long-term impact of glucose monitoring with the FreeStyle Libre on glycaemic control and hypoglycaemia awareness in people with type1 diabetes: Insights from the Association of British Clinical Diabetologists national audit. Diabetic medicine, 40(6), Article e15070. https://doi.org/10.1111/dme.15070

Aims: To investigate the change in glycated haemoglobin (HbA1c), hypoglycaemia awareness and diabetes-related distress in people with type 1 diabetes (T1D) using FreeStyle Libre (FSL) over a 2-year follow-up period. Methods: FSL user data from U.K wi... Read More about The long-term impact of glucose monitoring with the FreeStyle Libre on glycaemic control and hypoglycaemia awareness in people with type1 diabetes: Insights from the Association of British Clinical Diabetologists national audit.

Clinical and confidence outcomes following through-knee versus above-knee amputation : a quantitative study (2023)
Thesis
Boam, G. L. (2023). Clinical and confidence outcomes following through-knee versus above-knee amputation : a quantitative study. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4567461

Following surgery, patients with a major lower limb amputation face physical and mental health challenges. For clinicians and physiotherapists to reach a consensus and provide a suitable level of amputation for each patient, the understanding of post... Read More about Clinical and confidence outcomes following through-knee versus above-knee amputation : a quantitative study.