All Outputs (667)

UV-associated decline in systemic folate: implications for human nutrigenetics, health, and evolutionary processes (2016)
Journal Article
Lucock, M., Beckett, E., Martin, C., Jones, P., Furst, J., Yates, Z., Jablonski, N., Chaplin, G., & Veysey, M. (2017). UV-associated decline in systemic folate: implications for human nutrigenetics, health, and evolutionary processes. American Journal of Human Biology, 29(2), Article e22929. https://doi.org/10.1002/ajhb.22929

© 2016 Wiley Periodicals, Inc. Objectives: The purpose of this study was to examine whether UV exposure alters folate status according to C677T-MTHFR genotype, and to consider the relevance of this to human health and the evolutionary model of skin p... Read More about UV-associated decline in systemic folate: implications for human nutrigenetics, health, and evolutionary processes.

The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise (2016)
Journal Article
O’Doherty, A. F., Sathyapalan, T., Rigby, A. S., Ingle, L., & Carroll, S. (2018). The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise. European Journal of Nutrition, 57(1), 309-318. https://doi.org/10.1007/s00394-016-1320-z

© 2016 The Author(s) Purpose: The Oral Fat Tolerance Test (OFTT) is regarded as a repeatable measure used to assess postprandial triglyceride (TAG) levels, with higher levels observed in cardio-metabolic disorders. Acute aerobic exercise intervention... Read More about The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise.

Internet-based training of coronary artery patients: the Heart Cycle Trial (2016)
Journal Article
Skobel, E., Knackstedt, C., Martinez-Romero, A., Salvi, D., Vera-Munoz, C., Napp, A., Luprano, J., Bover, R., Glöggler, S., Bjarnason-Wehrens, B., Marx, N., Rigby, A., & Cleland, J. (2017). Internet-based training of coronary artery patients: the Heart Cycle Trial. Heart and vessels, 32(4), 408-418. https://doi.org/10.1007/s00380-016-0897-8

© 2016, Springer Japan. Low adherence to cardiac rehabilitation (CR) might be improved by remote monitoring systems that can be used to motivate and supervise patients and tailor CR safely and effectively to their needs. The main objective of this st... Read More about Internet-based training of coronary artery patients: the Heart Cycle Trial.

Sexually dimorphic gene expression in bovine conceptuses at the initiation of implantation (2016)
Journal Article
Forde, N., Maillo, V., O'Gaora, P., Simintiras, C. A., Sturmey, R. G., Ealy, A. D., Spencer, T. E., Gutierrez-Adan, A., Rizos, D., & Lonergan, P. (2016). Sexually dimorphic gene expression in bovine conceptuses at the initiation of implantation. Biology of Reproduction, 95(4), Article ARTN 92. https://doi.org/10.1095/biolreprod.116.139857

In cattle, maternal recognition of pregnancy occurs on Day 16 via secretion of interferon tau (IFNT) by the conceptus. The endometrium can distinguish between embryos with different developmental competencies. In eutherian mammals, X-chromosome inact... Read More about Sexually dimorphic gene expression in bovine conceptuses at the initiation of implantation.

Soy reduces bone turnover markers in women during early menopause: a randomized controlled trial (2016)
Journal Article
Sathyapalan, T., Aye, M., Rigby, A. S., Fraser, W. D., Thatcher, N. J., Kilpatrick, E. S., & Atkin, S. L. (2017). Soy reduces bone turnover markers in women during early menopause: a randomized controlled trial. Journal of Bone and Mineral Research, 32(1), 157-164. https://doi.org/10.1002/jbmr.2927

Menopausal estrogen loss leads to an increased bone loss. Soy isoflavones can act as selective estrogen receptor modulators, their role in bone turnover is unclear. The primary outcome was assessing changes in plasma bone turnover markers. The second... Read More about Soy reduces bone turnover markers in women during early menopause: a randomized controlled trial.

Pilot investigation of a virtual gastric band hypnotherapy intervention (2016)
Journal Article
Greetham, S., Goodwin, S., Wells, L., Whitham, C., Jones, H., Rigby, A., Sathyapalan, T., Reid, M., & Atkin, S. (2016). Pilot investigation of a virtual gastric band hypnotherapy intervention. International Journal of Clinical and Experimental Hypnosis, 64(4), 419-433. https://doi.org/10.1080/00207144.2016.1209037

This was a pilot investigation of 30 men and women with a BMI > 27kg/m² over a 24 week period. It aimed to determine whether virtual gastric band (VGB) hypnotherapy has an effect on weight loss in overweight adults, compared to relaxation hypnotherap... Read More about Pilot investigation of a virtual gastric band hypnotherapy intervention.

Chemotherapy treatment of multiple myeloma patients increases circulating levels of endothelial microvesicles (2016)
Journal Article
Gardiner, E., Madden, L., Maraveyas, A., Adesanya, M. A., Hall, J., & Sayala, H. (2016). Chemotherapy treatment of multiple myeloma patients increases circulating levels of endothelial microvesicles. Thrombosis Research, 146, 20-22. https://doi.org/10.1016/j.thromres.2016.08.017

Correspondence

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells (2016)
Journal Article
Sinclair, A., Park, L., Shah, M., Drotar, M., Calaminus, S., Hopcroft, L. E., Kinstrie, R., Guitart, A. V., Dunn, K., Abraham, S. A., Sansom, O., Michie, A. M., Machesky, L., Kranc, K. R., Graham, G. J., Pellicano, F., & Holyoake, T. L. (2016). CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells. Blood, 128(3), 371-383. https://doi.org/10.1182/blood-2015-08-661785

The regulation of hematopoietic stem cell (HSC) survival and self-renewal within the bone marrow (BM) niche is not well understood. We therefore investigated global transcriptomic profiling of normal human HSC/hematopoietic progenitor cells [HPCs], r... Read More about CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells.

Cerebral Regulation in Different Maximal Aerobic Exercise Modes (2016)
Journal Article
Pires, F. O., dos Anjos, C. A. S., Covolan, R. J. M., Pinheiro, F. A., St Clair Gibson, A., Noakes, T. D., Magalhães, F. H., & Ugrinowitsch, C. (in press). Cerebral Regulation in Different Maximal Aerobic Exercise Modes. Frontiers in Physiology, 7, Article 253. https://doi.org/10.3389/fphys.2016.00253

We investigated cerebral responses, simultaneously with peripheral and ratings of perceived exertion (RPE) responses, during different VO2MAX-matched aerobic exercise modes. Nine cyclists (VO2MAX of 57.5 ± 6.2 ml·kg−1·min−1) performed a maximal, cont... Read More about Cerebral Regulation in Different Maximal Aerobic Exercise Modes.

Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure (2016)
Journal Article
Cleland, J. G., Zhang, J., Pellicori, P., Dicken, B., Dierckx, R., Shoaib, A., Wong, K., Rigby, A., Goode, K., & Clark, A. L. (2016). Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure. JAMA Cardiology, 1(5), 539-547. https://doi.org/10.1001/jamacardio.2016.1161

Copyright © 2016 American Medical Association. All rights reserved. Importance: Detailed information on the prevalence, associations, and consequences of anemia and iron deficiency in epidemiologically representative outpatients with chronic heart fa... Read More about Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure.

A thematic synthesis of the experiences of adults living with hemodialysis (2016)
Journal Article
Reid, C., Seymour, J., & Jones, C. (2016). A thematic synthesis of the experiences of adults living with hemodialysis. Clinical journal of the American Society of Nephrology, 11(7), 1206-1218. https://doi.org/10.2215/CJN.10561015

Background and objectives In-center dialysis patients spend significant amounts of time on the dialysis unit; additionally managing ESKD affects many aspects of life outside the dialysis unit. To improve the care provided to patients requiring hemodi... Read More about A thematic synthesis of the experiences of adults living with hemodialysis.

Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry (2016)
Journal Article
Beckett, E., Duesing, K., Martin, C., Jones, P., Furst, J., King, K., Niblett, S., Yates, Z., Veysey, M., & Lucock, M. (2016). Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry. Journal of Nutrition and Intermediary Metabolism, 6, 8-15. https://doi.org/10.1016/j.jnim.2016.04.010

© 2016 The Authors. Published by Elsevier Inc. Vitamin D is known for its role in the regulation of gene expression via the Vitamin D receptor, a nuclear transcription factor. More recently, a role for Vitamin D in regulating DNA methylation has been... Read More about Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry.

A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication (2016)
Journal Article
Harwood, A., Smith, G. E., Cayton, T., Broadbent, E., & Chetter, I. C. (2016). A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication. Annals of vascular surgery, 34, 280-289. https://doi.org/10.1016/j.avsg.2016.02.009

Background Intermittent claudication (IC) is a common and debilitating symptom of peripheral arterial disease and is associated with a significant reduction in a sufferer's quality of life. Guidelines recommend a supervised exercise program (SEP) as... Read More about A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication.

Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis (2016)
Journal Article
Kotecha, D., Manzano, L., Krum, H., Rosano, G., Holmes, J., Altman, D. G., Collins, P. D., Packer, M., Wikstrand, J., Coats, A. J. S., Cleland, J. G. F., Kirchhof, P., von Lueder, T. G., Rigby, A. S., Andersson, B., Lip, G. Y., van Veldhuisen, D. J., Shibata, M. C., Wedel, H., Böhm, M., & Flather, M. D. (2016). Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis. BMJ, 353, i1855. https://doi.org/10.1136/bmj.i1855

© BMJ Publishing Group Ltd 2016. OBJECTIVES: To determine the efficacy and tolerability of β blockers in a broad age range of women and men with heart failure with reduced ejection fraction (HFrEF) by pooling individual patient data from placebo cont... Read More about Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis.

Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1 (2016)
Journal Article
Shoaib, A., Farag, M., Nasir, M., John, J., Gupta, S., Pellicori, P., Antony, R., Perveen, R., Rigby, A., Goode, K. M., Yassin, A., Clark, A. L., & Cleland, J. G. (2016). Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1. European journal of heart failure, 18(5), 556-563. https://doi.org/10.1002/ejhf.505

© 2016 The Authors. European Journal of Heart Failure. Aims Most studies on acute heart failure (HF) exploring the relationship between admissions to hospital for HF and subsequent outcomes have focused only on HF coded as the primary diagnosis, but... Read More about Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1.

A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study (2016)
Journal Article
Clewett, C. J., Langley, P., Bateson, A. D., Asghar, A., & Wilkinson, A. J. (2016). A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study. Health Technology Letters, 3(1), 2-5. https://doi.org/10.1049/htl.2015.0037

Hypoglycaemia unawareness is a common condition associated with increased risk of severe hypoglycaemia. The purpose of the authors' study was to develop a simple to use, home-based and non-invasive hypoglycaemia warning system based on electroencepha... Read More about A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study.

The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression (2016)
Journal Article
Jones, H. S., Gordon, A., Magwenzi, S. G., Naseem, K., Atkin, S. L., & Courts, F. L. (2016). The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression. Molecular Nutrition and Food Research, 60(4), 787-797. https://doi.org/10.1002/mnfr.201500751

Scope: Quercetin is reported to reduce blood pressure in hypertensive but not normotensive humans, but the role of endothelial redox signaling in this phenomenon has not been assessed. This study investigated the effects of physiologically obtainable... Read More about The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression.

Motivation for different types and doses of exercise during breast cancer chemotherapy: a Randomized Controlled Trial (2016)
Journal Article
Courneya, K. S., Segal, R. J., Vallerand, J. R., Forbes, C. C., Crawford, J. J., Dolan, L. B., Friedenreich, C. M., Reid, R. D., Gelmon, K., Mackey, J. R., & McKenzie, D. C. (2016). Motivation for different types and doses of exercise during breast cancer chemotherapy: a Randomized Controlled Trial. Annals of Behavioral Medicine, 50(4), 554-563. https://doi.org/10.1007/s12160-016-9782-z

Background
Exercise is beneficial for breast cancer patients during chemotherapy, but their motivation to perform different types and doses of exercise is unknown.

Purpose
The purpose of this study was to examine the anticipated and experienced... Read More about Motivation for different types and doses of exercise during breast cancer chemotherapy: a Randomized Controlled Trial.

Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people (2016)
Journal Article
Abbott, K. A., Veysey, M., Lucock, M., Niblett, S., King, K., Burrows, T., & Garg, M. L. (2016). Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people. British Journal of Nutrition, 115(8), 1379-1386. https://doi.org/10.1017/s0007114516000258

Copyright © The Authors 2016. The association between n-3 PUFA intake and type 2 diabetes (T2D) is unclear, and studies relating objective biomarkers of n-3 PUFA consumption to diabetic status remain limited. The aim of this study was to determine w... Read More about Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people.

The International Pulsar Timing Array: First data release (2016)
Journal Article
Verbiest, J. P., Lentati, L., Hobbs, G., Van Haasteren, R., Demorest, P. B., Janssen, G. H., …Zhu, X. J. (2016). The International Pulsar Timing Array: First data release. Monthly notices of the Royal Astronomical Society, 458(2), 1267-1288. https://doi.org/10.1093/mnras/stw347

The highly stable spin of neutron stars can be exploited for a variety of (astro)physical investigations. In particular, arrays of pulsars with rotational periods of the order of milliseconds can be used to detect correlated signals such as those cau... Read More about The International Pulsar Timing Array: First data release.