All Outputs (358)

Searching for Programme Theories for a realist evaluation: A case study comparing an academic database search and a simple Google search (2020)
Journal Article
Coleman, S., Wright, J. M., Nixon, J., Schoonhoven, L., Twiddy, M., & Greenhalgh, J. (2020). Searching for Programme Theories for a realist evaluation: A case study comparing an academic database search and a simple Google search. BMC Medical Research Methodology, 20(1), 217. https://doi.org/10.1186/s12874-020-01084-x

BACKGROUND: Realist methodologies are increasingly being used to evaluate complex interventions in health and social care. Programme theory (ideas and assumptions of how a particular intervention works) development is the first step in a realist eval... Read More about Searching for Programme Theories for a realist evaluation: A case study comparing an academic database search and a simple Google search.

Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study (2020)
Journal Article
James, S. L., Bertolacci, G. J., Castle, C. D., Dingels, Z. V., Fox, J. T., Hamilton, E. B., Roberts, N. L., Sylte, D. O., Henry, N. J., LeGrand, K. E., Banerjee, S. K., Abushouk, A. I., Adebayo, O. M., Adsuar, J. C., Advani, S. M., Alghnam, S. A., Almasri, N. A., Badiye, A. D., Bennett, D. A., Yaw Appiah, S. C., …Vos, T. (2020). Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study. Injury Prevention, 26, i125-i153. https://doi.org/10.1136/injuryprev-2019-043531

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. BACKGROUND: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disabili... Read More about Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study.

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17 (2020)
Journal Article
Reiner, R. C., Local Burden of Disease WaSH Collaborators, & Soyiri, I. (2020). Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17. The Lancet global health, 8(9), e1162-e1185. https://doi.org/10.1016/S2214-109X%2820%2930278-3

Background Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolutio... Read More about Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

Activities forgone because of chronic breathlessness: a cross-sectional, population prevalence study (2020)
Journal Article
Kochovska, S., Chang, S., Morgan, D. D., Ferreira, D., Sidhu, M., Saleh Moussa, R., Johnson, M. J., Ekström, M., & Currow, D. C. (2020). Activities forgone because of chronic breathlessness: a cross-sectional, population prevalence study. Palliative Medicine Reports, 1(1), 166-170. https://doi.org/10.1089/pmr.2020.0083

Background Chronic breathlessness is a prevalent, disabling syndrome affecting many people for years. Identifying the impact of chronic breathlessness on people’s activities in the general population is pivotal for designing symptom management strat... Read More about Activities forgone because of chronic breathlessness: a cross-sectional, population prevalence study.

The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis (2020)
Journal Article
Marshall, C., Jomeen, J., Huang, C., & Martin, C. (2020). The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 17(16), 1-19. https://doi.org/10.3390/ijerph17165778

Title: Systematic review and meta-analysis of the relationship between maternal personality disorder and early birth outcomes. Background: Women with personality disorder are at risk of social and emotional problems which impact deleteriously on eve... Read More about The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis.

Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness (2020)
Journal Article
Ekström, M., Johnson, M. J., Huang, C., & Currow, D. C. (2020). Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness. European respiratory journal, 56(2), Article 1902202. https://doi.org/10.1183/13993003.02202-2019

Copyright ©ERS 2020. BACKGROUND: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9 mm on a 100-mm visual analogue scale (VAS). We aimed to determine M... Read More about Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness.

Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study (2020)
Journal Article
Long, J., Meethan, K., Arundel, C., Clarke, E., Firth, A., Sylvester, M., & Chetter, I. (2020). Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study. Journal of tissue viability, 29(4), 342-347. https://doi.org/10.1016/j.jtv.2020.07.007

Background Research nurse involvement in trials is crucial to successful conduct, however their feedback on trial design and conduct is not necessarily always collected and shared. This study was designed to explore research nurse feedback in rela... Read More about Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study.

Microplastic contamination of drinking water: a systematic review. (2020)
Journal Article
Danopoulos, E., Twiddy, M., & Rotchell, J. M. (2020). Microplastic contamination of drinking water: a systematic review. PLoS ONE, 15(7 July), Article e0236838. https://doi.org/10.1371/journal.pone.0236838

Background Microplastics (MPs) are omnipresent in the environment, including the human food chain; a likely important contributor to human exposure is drinking water. Objective To undertake a systematic review of MP contamination of drinking water... Read More about Microplastic contamination of drinking water: a systematic review..

A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease (2020)
Journal Article
Luckett, T., San Martin, A., Currow, D. C., Johnson, M. J., Barnes-Harris, M. M. M., & Phillips, J. L. (2020). A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease. Palliative medicine, 34(10), 1291-1304. https://doi.org/10.1177/0269216320940153

Background: Chronic obstructive pulmonary disease and lung cancer are both life-limiting diseases that confer burden in the form of symptoms and affect functioning and quality of life. Comparing burden between these diseases is of interest to determi... Read More about A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease.

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Local Burden of Disease Diarrhoea Collaborators, & Soyiri, I. (2020). Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*. The Lancet global health, 8(8), e1038-e1060. https://doi.org/10.1016/S2214-109X%2820%2930230-8

Background Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years w... Read More about Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*.

COVID-19: guidance on palliative care from a European Respiratory Society international task force (2020)
Journal Article
Janssen, D. J., Maddocks, M., Janssen, D. J. A., Ekström, M., Currow, D. C., Johnson, M. J., Maddocks, M., Simonds, A. K., Tonia, T., & Marsaa, K. (2020). COVID-19: guidance on palliative care from a European Respiratory Society international task force. European respiratory journal, 56(3), 2002583. https://doi.org/10.1183/13993003.02583-2020

Copyright ©ERS 2020. BACKGROUND: Many people are dying from coronavirus disease 2019 (COVID-19), but consensus guidance on palliative care in COVID-19 is lacking. This new life-threatening disease has put healthcare systems under pressure, with the i... Read More about COVID-19: guidance on palliative care from a European Respiratory Society international task force.

Letter in Response to Grobler AC, Lee K. Intention-To-Treat Analyses for Randomized Controlled Trials in Hospice/Palliative Care Enhanced by Principled Methods to Handle Missing Data (2020)
Journal Article
Huang, C., Kochovska, S., & Currow, D. C. (2020). Letter in Response to Grobler AC, Lee K. Intention-To-Treat Analyses for Randomized Controlled Trials in Hospice/Palliative Care Enhanced by Principled Methods to Handle Missing Data. Journal of pain and symptom management, 60(4), e30-e31. https://doi.org/10.1016/j.jpainsymman.2020.07.004

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., Long, J., Rooms, M., & Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Opioids for breathlessness: a narrative review (2020)
Journal Article
Currow, D. C., Johnson, M. J., Pollack, A., Ferreira, D. H., Kochovska, S., Ekström, M., & Harrison, C. (2020). Opioids for breathlessness: a narrative review. BMJ Supportive & Palliative Care, 10(3), 287-295. https://doi.org/10.1136/bmjspcare-2020-002314

ABSTRACT Chronic breathlessness is a disabling and distressing condition for which there is a growing evidence base for a range of interventions. Non-pharmacological interventions are the mainstay of management and should be optimised prior to use... Read More about Opioids for breathlessness: a narrative review.

A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors (2020)
Journal Article
Salawu, A., Green, A., Crooks, M. G., Brixey, N., Ross, D. H., & Sivan, M. (2020). A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors. International Journal of Environmental Research and Public Health, 17(13), 1-13. https://doi.org/10.3390/ijerph17134890

A global pandemic of a new highly contagious disease called COVID-19 resulting from coronavirus (severe acute respiratory syndrome (SARS)-Cov-2) infection was declared in February 2020. Though primarily transmitted through the respiratory system, oth... Read More about A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors.

Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study (2020)
Journal Article
Baddeley, E., Bravington, A., Johnson, M., Currow, D., Murtagh, F. E., Boland, E., Obita, G., Nelson, A., Seddon, K., Oliver, A., Noble, S., & Boland, J. (2020). Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study. BMJ open, 10(6), Article 039154. https://doi.org/10.1136/bmjopen-2020-039154

INTRODUCTION: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.

Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial (2020)
Journal Article
Cardozo, W., Baker, R., Berger, C., Chapman, S., Codd, R., Coyne, P., Evans, M., Davies, J., Harries, D., Hicks, L., Harries, R., Jayamanne, H., Lockwood, S., Kelly, S., Madhavan, A., Plusa, S., McCallum, I., Moriarty, C., Nassa, H., Priestley, M., …Brown, J. (in press). Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial. British journal of surgery, https://doi.org/10.1002/bjs.11703

Abstract Background Approximately 30,000 people per annum undergo major, emergency abdominal, gastrointestinal surgery, of which 36% (~10,800) are carried out for emergency colorectal pathology. Approximately 14% of all patients requiring emergency... Read More about Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial.

The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial (2020)
Journal Article
Nicholls, A. R., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., Cope, E., & Ntoumanis, N. (2020). The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial. International Journal of Drug Policy, 82, Article 102820. https://doi.org/10.1016/j.drugpo.2020.102820

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial.

Patients’ and caregivers’ experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study (2020)
Journal Article
Ferreira, D. H., Boland, J. W., Kochovska, S., Honson, A., Phillips, J. L., & Currow, D. C. (2020). Patients’ and caregivers’ experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study. Palliative medicine, 34(8), 1078-1087. https://doi.org/10.1177/0269216320929549

Background: Chronic breathlessness is a disabling syndrome that profoundly impacts patients’ and caregivers’ lives. Driving is important for most people, including those with advanced disease. Regular, low-dose, sustained-release morphine safely red... Read More about Patients’ and caregivers’ experiences of driving with chronic breathlessness before and after regular low-dose sustained-release morphine: A qualitative study.

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Soyiri, I., & Local Burden of Disease Diarrhoea Collaborators. (2020). Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*. Lancet, 395(10239), 1779-1801. https://doi.org/10.1016/S0140-6736%2820%2930114-8

Background Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable t... Read More about Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*.