All Outputs (170)

Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model
Presentation / Conference Contribution
Ji, B., Yang, Q., Genever, P. G., & Fagan, M. J. Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model

Multiple myeloma (MM)-induced bone disease is mortal for most MM patients. Bisphosphonates are first-line treatment for MM-induced bone disease, since it can inhibit osteoclast activity and the resultant bone resorption by suppressing the differentia... Read More about Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model.

Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation
Presentation / Conference Contribution
Phillips, R., Grunchec, J. A., Ward, J. W., Fagan, M. J., Dobson, C. A., Langton, C. M., & Sisias, G. Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation

Adult human bone is constantly being renewed by a process known as remodelling. For cancellous bone this renewal process occurs at the interface between bone and marrow where bone is depleted by osteoclasts and rebuilt by osteoblasts. This remodellin... Read More about Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation.

The U wave in atrial fibrillation
Presentation / Conference Contribution
Langley, P., Bourke, J. P., & Murray, A. The U wave in atrial fibrillation. Presented at 2015 Computing in Cardiology Conference (CinC)

The U wave in ECGs of patients is difficult to observe because it is hidden under the atrial fibrillatory wave. Measurement and characteristics of the U wave in atrial fibrillation have not previously been described. Beat averaging was used to reveal... Read More about The U wave in atrial fibrillation.

The effect of beat interval on ventricular repolarisation in atrial fibrillation
Presentation / Conference Contribution
Al-Karadi, M. S., Wilkinson, A. J., & Langley, P. (2018, September). The effect of beat interval on ventricular repolarisation in atrial fibrillation. Presented at 2018 Computing in Cardiology Conference (CinC), Maastricht, The Netherlands

© 2018 Creative Commons Attribution. Atrial fibrillation (AF) is characterised by rapid beat interval changes. The aim of the study was to investigate the effect of such changes on ECG ventricular repolarisation characteristics. In 10 AF recordings b... Read More about The effect of beat interval on ventricular repolarisation in atrial fibrillation.

Abnormal heart sounds detected from short duration unsegmented phonocardiograms by wavelet entropy
Presentation / Conference Contribution
Langley, P., & Murray, A. Abnormal heart sounds detected from short duration unsegmented phonocardiograms by wavelet entropy

© 2016 CCAL. Segmentation of the characteristic heart sounds is thought to be an essential requirement for the automatic classification of phonocardiograms. The aim of this work was to test the feasibility of classification using short duration, unse... Read More about Abnormal heart sounds detected from short duration unsegmented phonocardiograms by wavelet entropy.

Comparison of body surface and intracardiac ECG recordings in patients with atrial fibrillation during electrophysiological studies
Presentation / Conference Contribution
Bojarnejad, M., Blake, J., Bourke, J. P., Murray, A., & Langley, P. Comparison of body surface and intracardiac ECG recordings in patients with atrial fibrillation during electrophysiological studies. Presented at World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China

Atrial fibrillation (AF) dominant frequency (DF) is thought to reflect the degree of organisation of underlying atrial activity (AA). Our aim was to evaluate the relationship between the DFs from the body surface electrocardiogram (ECG) and intracard... Read More about Comparison of body surface and intracardiac ECG recordings in patients with atrial fibrillation during electrophysiological studies.

P014 | THE INFLUENCE OF SUBCHONDRAL BONE CYSTS ON TISSUE PRESSURES IN THE TIBIOTALAR JOINT
Presentation / Conference Contribution
Talbott, H., Wilkins, R., Redmond, A., Brockett, C., & Mengoni, M. P014 | THE INFLUENCE OF SUBCHONDRAL BONE CYSTS ON TISSUE PRESSURES IN THE TIBIOTALAR JOINT. Presented at 13th Annual Congress of European Association for Haemophilia and Allied Disorders 2020, 5–7 February 2020, The Hague, The Netherlands

Introduction: Subchondral bone cysts are an indicator of late stage
haemophilic joint disease (HJD); however, the implication of these
cysts on joint health is little understood. The aim of this study was
to assess, computationally, the influence... Read More about P014 | THE INFLUENCE OF SUBCHONDRAL BONE CYSTS ON TISSUE PRESSURES IN THE TIBIOTALAR JOINT.

M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication
Presentation / Conference Contribution
Moetazedian, A., Candeo, A., Bassi, A., Cox, L. R., Grover, L. M., & Poologasundarampillai, G. (2023, June). M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication. Presented at 2nd International Conference on Medical Devices: Materials, Mechanics and Manufacturing (ICMD3M 2023), Corfu, Greece

Microfluidics market is the fastest growing research area in the world, and they have shown much promise in biofabrication and 3D bioprinting of tissues and organs. However, microfluidics is conventionally produced using drawn-out and expensive litho... Read More about M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication.

Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading
Presentation / Conference Contribution
Moetazedian, A., Gleadall, A., Mele, E., & Silberschmidt, V. V. (2020, June). Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading. Presented at 1st Virtual European Conference on Fracture, Online

With a general cautious attitude regarding the anisotropic properties of upright 3D-printed parts, there is a lack of fundamental understanding of behavior of 3D-printed polymers under cyclic loading condition, which is more representative of real-li... Read More about Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading.

Can vibration statistics of an idealised sine wave be used to examine fatigue properties of porcine trabecular bone?
Presentation / Conference Contribution
Shanker, T.-A., & Zioupos, P. (2017, September). Can vibration statistics of an idealised sine wave be used to examine fatigue properties of porcine trabecular bone?. Presented at HRV2017: 52nd Human Response to Vibration Conference & Workshop, Shrivenham, UK

Fatigue testing on trabecular bone has been performed throughout the years, the data contained could be of use to researchers attempting to find a qualitative link between whole-body vibration and spinal damage. 10 porcine trabecular cores were testi... Read More about Can vibration statistics of an idealised sine wave be used to examine fatigue properties of porcine trabecular bone?.