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The effect of beat interval on ventricular repolarisation in atrial fibrillation

Al-Karadi, Marwa S; Wilkinson, Antony J; Langley, Philip


Marwa S Al-Karadi

Antony J Wilkinson


Atrial fibrillation (AF) is characterised by rapid beat interval changes. The aim of the study was to investigate the effect of such changes on ECG ventricular repolarisation characteristics. In 10 AF recordings beat averaging of lead V4 was used to generate averaged T waves where the preceding beat interval (R-R) was either short (625+/-25 ms) or long (1075+/-25 ms). The amplitudes of T wave (T amp) and T wave end, defined as the TU nadir, (TUn amp), and the intervals for R wave to T wave peak (R-T) and R wave to T wave end (R-TUn) where measured from these average beats. Difference in measured T wave characteristics between short and long beat intervals were quantified. All measurements increased significantly for long preceding beat intervals compared to short: T amp (mean± SD) 0.31±0.17 mV (short) vs 0.35±0.20 mV (long) (p = 0.04); TUn amp 0.00±0.02 mV (short) vs 0.03±0.03 mV (long) (p = 0.009); R-T 251.7±13.5 ms (short) vs 264.2±12 ms (long) (p = 0.002) and R-TUn 376.5±31 ms (short) vs 392±26.5 ms (long) (p=0.027). ECG T wave characteristics are significantly affected by preceding ventricular beat interval in AF.


Al-Karadi, M. S., Wilkinson, A. J., & Langley, P. (2019). The effect of beat interval on ventricular repolarisation in atrial fibrillation.

Conference Name Computing in cardiology
Conference Location Maastricht, The Netherlands
Start Date Sep 16, 2018
End Date Sep 26, 2018
Acceptance Date Feb 1, 2019
Online Publication Date Feb 1, 2019
Publication Date Feb 1, 2019
Deposit Date Mar 1, 2019
Publicly Available Date Mar 1, 2019
Volume 45
Series Title Computing in cardiology papers on-line
Series ISSN 2325-8861
Public URL
Publisher URL


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