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Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls (2014)
Journal Article
Curtis, N., Witzel, U., & Fagan, M. J. (2014). Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls. Folia primatologica, 85(2), 77-87. https://doi.org/10.1159/000357526

Cranial sutures are an essential part of the growing skull, allowing bones to increase in size during growth, with their morphology widely believed to be dictated by the forces and displacements that they experience. The zygomaticotemporal suture in... Read More about Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls.

The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players (2014)
Journal Article
Gosselin, G., & Fagan, M. J. (2014). The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players. Journal of sports science & medicine, 13(2), 329-337

Neck muscle fatigue has been shown to alter an individual’s balance in a similar way to that reported in subjects suffering from neck pain or subjects that have suffered a neck injury. The main purpose of the present study was to quantify the effects... Read More about The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players.

A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors (2014)
Journal Article
Ji, B., Yang, Q., Genever, P. G., Patton, R. J., & Fagan, M. J. (2014). A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 228(10), 1035-1042. https://doi.org/10.1177/0954411914554633

© IMechE 2014. Bone remodelling is a vital process which enables bone to repair, renew and optimize itself. Disorders in the bone remodelling process are inevitably manifested in bone-related diseases, such as hypothyroidism, primary hyperparathyroid... Read More about A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors.

Erratum: Cranial sutures work collectively to distribute strain throughout the reptile skull (Journal of The Royal Society Interface (2013) 10 (2013044) DOI: 10.1098/rsif.2013.0442) (2013)
Journal Article
Curtis, N., Jones, M. E., Evans, S. E., O'Higgins, P., & Fagan, M. J. (2013). Erratum: Cranial sutures work collectively to distribute strain throughout the reptile skull (Journal of The Royal Society Interface (2013) 10 (2013044) DOI: 10.1098/rsif.2013.0442). Journal of the Royal Society interface / the Royal Society, 10(87), Article 2013044. https://doi.org/10.1098/rsif.2013.0584

Figure 4 was presented incorrectly, with (a) and (b) displaying the same bite position. The corrected figure below shows different bite positions for (a) and (b) as was initially intended.

The importance of accurate muscle modelling for biomechanical analyses: A case study with a lizard skull (2013)
Journal Article
Gröning, F., Jones, M. E., Curtis, N., Herrel, A., O'Higgins, P., Evans, S. E., & Fagan, M. J. (2013). The importance of accurate muscle modelling for biomechanical analyses: A case study with a lizard skull. Journal of the Royal Society interface / the Royal Society, 10(84), Article 20130216. https://doi.org/10.1098/rsif.2013.0216

Computer-based simulation techniques such as multi-body dynamics analysis are becoming increasingly popular in the field of skull mechanics. Multi-body models can be used for studying the relationships between skull architecture, muscle morphology an... Read More about The importance of accurate muscle modelling for biomechanical analyses: A case study with a lizard skull.

Cranial sutures work collectively to distribute strain throughout the reptile skull (2013)
Journal Article
Curtis, N., Fagan, M. J., Evans, S. E., Jones, M. E. H., & O'Higgins, P. (2013). Cranial sutures work collectively to distribute strain throughout the reptile skull. Journal of the Royal Society interface / the Royal Society, 10(86), 1-9. https://doi.org/10.1098/rsif.2013.0442

The skull is composed of many bones that come together at sutures. These sutures are important sites of growth, and as growth ceases some become fused while others remain patent. Their mechanical behaviour and how they interact with changing form and... Read More about Cranial sutures work collectively to distribute strain throughout the reptile skull.

Characteristics of atrial fibrillation cycle length predict restoration of sinus rhythm by catheter ablation (2013)
Journal Article
Di Marco, L. Y., Raine, D., Bourke, J. P., & Langley, P. (2013). Characteristics of atrial fibrillation cycle length predict restoration of sinus rhythm by catheter ablation. Heart rhythm : the official journal of the Heart Rhythm Society, 10(9), 1303-1310. https://doi.org/10.1016/j.hrthm.2013.06.007

Background Successful termination of atrial fibrillation (AF) during catheter ablation (CA) is associated with arrhythmia-free follow-up. Preablation factors such as mean atrial fibrillation cycle length (AFCL) predict the likelihood of AF terminatio... Read More about Characteristics of atrial fibrillation cycle length predict restoration of sinus rhythm by catheter ablation.

Accuracy of algorithms for detection of atrial fibrillation from short duration beat interval recordings (2012)
Journal Article
Langley, P., Dewhurst, M., Di Marco, L. Y., Adams, P., Dewhurst, F., Mwita, J. C., Walker, R., & Murray, A. (2012). Accuracy of algorithms for detection of atrial fibrillation from short duration beat interval recordings. Medical engineering & physics, 34(10), 1441-1447. https://doi.org/10.1016/j.medengphy.2012.02.002

Atrial fibrillation (AF) is characterised by highly variable beat intervals. The aims of the study were to assess the accuracy of AF detection algorithms from short analysis durations and to validate prospectively the accuracy on a large community-ba... Read More about Accuracy of algorithms for detection of atrial fibrillation from short duration beat interval recordings.

Comparison of body surface and intracardiac ECG recordings in patients with atrial fibrillation during electrophysiological studies (2012)
Presentation / Conference Contribution
Bojarnejad, M., Blake, J., Bourke, J. P., Murray, A., & Langley, P. Comparison of body surface and intracardiac ECG recordings in patients with atrial fibrillation during electrophysiological studies. Presented at World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China

Atrial fibrillation (AF) dominant frequency (DF) is thought to reflect the degree of organisation of underlying atrial activity (AA). Our aim was to evaluate the relationship between the DFs from the body surface electrocardiogram (ECG) and intracard... Read More about Comparison of body surface and intracardiac ECG recordings in patients with atrial fibrillation during electrophysiological studies.

The Head and Neck Anatomy of Sea Turtles (Cryptodira: Chelonioidea) and Skull Shape in Testudines (2012)
Journal Article
Jones, M. E., Werneburg, I., Curtis, N., Penrose, R., O'Higgins, P., Fagan, M. J., & Evans, S. E. (2012). The Head and Neck Anatomy of Sea Turtles (Cryptodira: Chelonioidea) and Skull Shape in Testudines. PLoS ONE, 7(11), Article e47852. https://doi.org/10.1371/journal.pone.0047852

Background: Sea turtles (Chelonoidea) are a charismatic group of marine reptiles that occupy a range of important ecological roles. However, the diversity and evolution of their feeding anatomy remain incompletely known. Methodology/Principal Finding... Read More about The Head and Neck Anatomy of Sea Turtles (Cryptodira: Chelonioidea) and Skull Shape in Testudines.

The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation (2012)
Journal Article
Jahani, M., Genever, P. G., Patton, R. J., Ahwal, F., & Fagan, M. J. (2012). The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation. Journal of biomechanics, 45(16), 2876-2883. https://doi.org/10.1016/j.jbiomech.2012.08.005

Osteocytes play a critical role in the regulation of bone remodelling by translating strain due to mechanical loading into biochemical signals transmitted through the interconnecting lacuno-canalicular network to bone lining cells (BLCs) on the bone... Read More about The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation.

Comparing the distribution of strains with the distribution of bone tissue in a human mandible: a finite element study (2012)
Journal Article
Gröning, F., Fagan, M., & O'Higgins, P. (2013). Comparing the distribution of strains with the distribution of bone tissue in a human mandible: a finite element study. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 296(1), 9-18. https://doi.org/10.1002/ar.22597

Comparative anatomy and experimental studies suggest that the mass and distribution of tissue within a bone is adapted to the strains the bone experiences during function. Finite element analysis is a powerful tool that can be used to investigate thi... Read More about Comparing the distribution of strains with the distribution of bone tissue in a human mandible: a finite element study.

Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study (2012)
Journal Article
Fitton, L. C., Shi, J. F., Fagan, M. J., & O'Higgins, P. (2012). Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study. Journal of anatomy, 221(1), 55-68. https://doi.org/10.1111/j.1469-7580.2012.01516.x

Biomechanical analyses are commonly conducted to investigate how craniofacial form relates to function, particularly in relation to dietary adaptations. However, in the absence of corresponding muscle activation patterns, incomplete muscle data recor... Read More about Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study.

Developing a musculoskeletal model of the primate skull: Predicting muscle activations, bite force, and joint reaction forces using multibody dynamics analysis and advanced optimisation methods (2012)
Journal Article
Shi, J., Curtis, N., Fitton, L. C., O'Higgins, P., & Fagan, M. J. (2012). Developing a musculoskeletal model of the primate skull: Predicting muscle activations, bite force, and joint reaction forces using multibody dynamics analysis and advanced optimisation methods. Journal of Theoretical Biology, 310, 21-30. https://doi.org/10.1016/j.jtbi.2012.06.006

An accurate, dynamic, functional model of the skull that can be used to predict muscle forces, bite forces, and joint reaction forces would have many uses across a broad range of disciplines. One major issue however with musculoskeletal analyses is t... Read More about Developing a musculoskeletal model of the primate skull: Predicting muscle activations, bite force, and joint reaction forces using multibody dynamics analysis and advanced optimisation methods.

Shearing Mechanics and the Influence of a Flexible Symphysis During Oral Food Processing in Sphenodon (Lepidosauria: Rhynchocephalia) (2012)
Journal Article
Jones, M. E. H., Evans, S. E., Curtis, N., O'Higgins, P., & Fagan, M. J. (2012). Shearing Mechanics and the Influence of a Flexible Symphysis During Oral Food Processing in Sphenodon (Lepidosauria: Rhynchocephalia). Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 295(7), 1075-1091. https://doi.org/10.1002/ar.22487

Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms (2012)
Journal Article
Abdul Rahman, M., Mazari, F., Khan, J. A., Madden, L., McCollum, P., Shahin, Y., Chetter, I., Greenman, J., Fagan, M., & Smith, G. (2012). Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms. Annals of vascular surgery, 26(3), 322-329. https://doi.org/10.1016/j.avsg.2011.08.015

BACKGROUND The influence of intraluminal thrombus (ILT) on the proteolytic environment within the wall of an abdominal aortic aneurysm (AAA) is unknown. This is the first study to examine the correlation between ILT thickness and the levels of matrix... Read More about Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms.

Functional evolution of the feeding system in rodents (2012)
Journal Article
Cox, P. G., Rayfield, E. J., Fagan, M. J., Herrel, A., Pataky, T. C., & Jeffery, N. (2012). Functional evolution of the feeding system in rodents. PLoS ONE, 7(4), e36299. https://doi.org/10.1371/journal.pone.0036299

The masticatory musculature of rodents has evolved to enable both gnawing at the incisors and chewing at the molars. In particular, the masseter muscle is highly specialised, having extended anteriorly to originate from the rostrum. All living rodent... Read More about Functional evolution of the feeding system in rodents.

Modeling the human mandible under masticatory loads: which input variables are important? (2012)
Journal Article
Gröning, F., Fagan, M., & O'higgins, P. (2012). Modeling the human mandible under masticatory loads: which input variables are important?. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 295(5), 853-863. https://doi.org/10.1002/ar.22455

Finite element analyses (FEA) that have simulated masticatory loadings of the human mandible differ significantly with regard to their basic input variables such as material properties, constraints, and applied forces. With sensitivity analyses it is... Read More about Modeling the human mandible under masticatory loads: which input variables are important?.

Improving the validation of finite element models with quantitative full-field strain comparisons (2012)
Journal Article
Gröning, F., Bright, J. A., Fagan, M. J., & O'Higgins, P. (2012). Improving the validation of finite element models with quantitative full-field strain comparisons. Journal of biomechanics, 45(8), 1498-1506. https://doi.org/10.1016/j.jbiomech.2012.02.009

The techniques used to validate finite element (FE) models against experimental results have changed little during the last decades, even though the traditional approach of using single point measurements from strain gauges has major limitations: the... Read More about Improving the validation of finite element models with quantitative full-field strain comparisons.