All Outputs (7)

Area-level socioeconomic inequalities in activities of daily living disability-free life expectancy in England: a modelling study (2025)
Journal Article
Davies, L. E., Sinclair, D. R., Todd, C., Hanratty, B., Matthews, F. E., & Kingston, A. (in press). Area-level socioeconomic inequalities in activities of daily living disability-free life expectancy in England: a modelling study. The Lancet Healthy Longevity, 6(4), Article 100700. https://doi.org/10.1016/j.lanhl.2025.100700

Background: More evidence of socioeconomic inequalities in disability-free life expectancy (DFLE) is needed to help develop approaches to narrow the gap between the most and least socioeconomically deprived people. Activities of daily living (ADL) di... Read More about Area-level socioeconomic inequalities in activities of daily living disability-free life expectancy in England: a modelling study.

Organising general practice for care homes: a multi-method study (2025)
Journal Article
Hanratty, B., Stocker, R., Sinclair, D., Brittain, K., Spilsbury, K., Stow, D., Robinson, L., & Matthews, F. E. (2025). Organising general practice for care homes: a multi-method study. Health and Social Care Delivery Research, 13(11), https://doi.org/10.3310/YNDV6358

Background: General practice provides first-line National Health Service care for around 400,000 care home residents. Good primary care can enhance residents' health and well-being and optimise use of hospital services.
Objectives: This study aimed... Read More about Organising general practice for care homes: a multi-method study.

Brain network connectivity underlying neuropsychiatric symptoms in prodromal Lewy body dementia (2025)
Journal Article
Wright, L. M., Donaghy, P. C., Burn, D. J., Taylor, J.-P., O'OBrien, J. T., Yarnall, A. J., Matthews, F. E., Firbank, M. J., Sigurdsson, H. P., Schumacher, J., Thomas, A. J., & Lawson, R. A. (in press). Brain network connectivity underlying neuropsychiatric symptoms in prodromal Lewy body dementia. Neurobiology of Aging, https://doi.org/10.1016/j.neurobiolaging.2025.04.007

Neuropsychiatric symptoms (NPS) are prevalent, emerge early, and are associated with poorer outcomes in Lewy body dementia (LBD). Research suggests NPS may reflect LBD-related dysfunction in distributed neuronal networks. This study investigated NPS... Read More about Brain network connectivity underlying neuropsychiatric symptoms in prodromal Lewy body dementia.

Differences in the risk of frailty based on care receipt, unmet care needs and socio-economic inequalities: A longitudinal analysis of the English Longitudinal Study of Ageing (2025)
Journal Article
Sinclair, D. R., Maharani, A., Clegg, A., Hanratty, B., Tampubolon, G., Todd, C., Wittenberg, R., O’Neill, T. W., & Matthews, F. E. (2025). Differences in the risk of frailty based on care receipt, unmet care needs and socio-economic inequalities: A longitudinal analysis of the English Longitudinal Study of Ageing. The Journal of Frailty & Aging, 14(2), Article 100012. https://doi.org/10.1016/j.tjfa.2025.100012

Background: The older population is increasingly reliant on social care, especially those who are frail. However, an estimated 1.5 million people over 65 in England have unmet care needs. The relationship between receiving care, or receiving insuffic... Read More about Differences in the risk of frailty based on care receipt, unmet care needs and socio-economic inequalities: A longitudinal analysis of the English Longitudinal Study of Ageing.

Building ADMISSION – A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital (2025)
Journal Article
Witham, M. D., Bartle, V., Bellass, S., Bunn, J. G., Cartner, D., Cordell, H. J., Doal, R., Evison, F., Gallier, S., Harris, S., Hillman, S. J., Holding, R., Leroux, P., Marshall, T., Matthews, F. E., Missier, P., Nair, A., Osman, M., Pearson, E. R., Plummer, C., …Sayer, A. A. (2025). Building ADMISSION – A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital. Journal of Multimorbidity and Comorbidity, 15, https://doi.org/10.1177/26335565251317940

Background
Multiple long-term conditions (MLTCs; commonly referred to as multimorbidity) are highly prevalent among people admitted to hospital and are therefore of critical importance to hospital-based healthcare systems. To date, most research on... Read More about Building ADMISSION – A research collaborative to transform understanding of multiple long-term conditions for people admitted to hospital.

Cognitive reserve and its impact on cognitive and functional abilities, physical activity and quality of life following a diagnosis of dementia: longitudinal findings from the Improving the experience of Dementia and Enhancing Active Life (IDEAL) study (2025)
Journal Article
Gamble, L. D., Clare, L., Opdebeeck, C., Martyr, A., Jones, R. W., Rusted, J. M., Pentecost, C., Thom, J. M., & Matthews, F. E. (2025). Cognitive reserve and its impact on cognitive and functional abilities, physical activity and quality of life following a diagnosis of dementia: longitudinal findings from the Improving the experience of Dementia and Enhancing Active Life (IDEAL) study. Age and ageing, 54(1), Article afae284. https://doi.org/10.1093/ageing/afae284

Background: The concept of cognitive reserve may explain inter-individual differences in susceptibility to neuropathological changes. Studies suggest that experiences over a lifetime impact on cognitive reserve, and it is hypothesised that following... Read More about Cognitive reserve and its impact on cognitive and functional abilities, physical activity and quality of life following a diagnosis of dementia: longitudinal findings from the Improving the experience of Dementia and Enhancing Active Life (IDEAL) study.

Ecological study of the association between the English national vaccination programme and area deprivation inequalities in COVID-19 mortality (2025)
Journal Article
Bennett, N., Bambra, C., Sinclair, D., Todd, A., & Matthews, F. (2025). Ecological study of the association between the English national vaccination programme and area deprivation inequalities in COVID-19 mortality. BMJ open, 15(1), Article e085195. https://doi.org/10.1136/bmjopen-2024-085195

Objective To understand how area deprivation inequalities in COVID-19 mortality changed during the national vaccination programme in England and to identify the extent to which these inequalities might be explained by unequal vaccination uptake. Desi... Read More about Ecological study of the association between the English national vaccination programme and area deprivation inequalities in COVID-19 mortality.