All Outputs (12467)

Roux-en-Y gastric bypass, adjustable gastric banding, or sleeve gastrectomy for severe obesity: the By-Band-Sleeve multi-centre, open label, three-group randomised controlled trial (2025)
Journal Article
The By-Band-Sleeve Collaborative Group, Blazeby, J., Rogers, C., Reeves, B., Welbourn, R., Mazza, G., Gidman, E., Kanavou, S., Edwards, D., Maishman, R., Pike, K., Wordsworth, S., Pouwels, K., Doble, B., Fermont, J., Koleva Kolarova, R., Blencowe, N., Byrne, J., Thompson, J., Pouwels, K., …Edmond, J. (2025). Roux-en-Y gastric bypass, adjustable gastric banding, or sleeve gastrectomy for severe obesity: the By-Band-Sleeve multi-centre, open label, three-group randomised controlled trial. Lancet Diabetes and Endocrinology, 13(5), 410-426. https://doi.org/10.1016/S2213-8587%2825%2900025-7+

Background
The health risks of severe obesity can be reduced with metabolic and bariatric surgery (MBS), but it is uncertain which operation is most effective or cost-effective. We compared Roux-en-Y gastric bypass (RYGB), adjustable gastric band (A... Read More about Roux-en-Y gastric bypass, adjustable gastric banding, or sleeve gastrectomy for severe obesity: the By-Band-Sleeve multi-centre, open label, three-group randomised controlled trial.

A pilot three arm randomised controlled trial and qualitative study of extracorporeal shockwave therapy for diabetic foot ulcer healing (SOLEFUL): A study protocol (2025)
Journal Article
Twiddy, M., Hitchman, L., Iglesias, C., Chetter, I. C., Russell, D., & Smith, G. (2025). A pilot three arm randomised controlled trial and qualitative study of extracorporeal shockwave therapy for diabetic foot ulcer healing (SOLEFUL): A study protocol. International wound journal, 22(4), Article e70176. https://doi.org/10.1111/iwj.70176

The development of effective interventions for diabetes-related foot ulcers (DFU) healing is vital. This protocol outlines a pilot trial and qualitative study investigating ESWT in DFU healing. A pilot three arm placebo controlled double-blinded rand... Read More about A pilot three arm randomised controlled trial and qualitative study of extracorporeal shockwave therapy for diabetic foot ulcer healing (SOLEFUL): A study protocol.

Oxygen Concentration Plays a Critical Role in Fibrinogen-Mediated Platelet Activation via Inactivation of αIIbβ3 and Modulation of Fibrinogen (2025)
Journal Article
Leonard, S. V. L., Booth, Z., Naylor-Adamson, L., Bibby, L., Wraith, K. S., Pula, G., Arman, M., & Calaminus, S. D. J. (2025). Oxygen Concentration Plays a Critical Role in Fibrinogen-Mediated Platelet Activation via Inactivation of αIIbβ3 and Modulation of Fibrinogen. Biomolecules, 15(4), Article 501. https://doi.org/10.3390/biom15040501

In the vascular system, pathological conditions that cause hypoxia are associated with increased platelet activity and thrombosis. Using a platelet spreading assay, we show that severe hypoxia (i.e., 1%), venous (i.e., 5%), and, surprisingly, arteria... Read More about Oxygen Concentration Plays a Critical Role in Fibrinogen-Mediated Platelet Activation via Inactivation of αIIbβ3 and Modulation of Fibrinogen.

Defining marine rewilding can help guide theory and practice in marine conservation (2025)
Journal Article
Brooker, E., Midgley, G., Burns, N., Trotman, C. E., Gregory, A., & Hopkins, C. R. (2025). Defining marine rewilding can help guide theory and practice in marine conservation. Communications Earth & Environment, 6(1), Article 241. https://doi.org/10.1038/s43247-025-02155-x

Public concern over global climate change and biodiversity loss has accelerated international efforts to restore natural ecosystems through nature-based solutions. Rewilding is a growing conservation approach encompassing the recovery of ecological a... Read More about Defining marine rewilding can help guide theory and practice in marine conservation.

Association of Complement Proteins with C Reactive Protein in Non-Obese Women with and Without Polycystic Ovary Syndrome (2025)
Journal Article
Butler, A. E., Moin, A. S. M., Begam, H. H., Waris, S., Azeez, J. M., Sathyapalan, T., Atkin, S. L., & Brennan, E. (2025). Association of Complement Proteins with C Reactive Protein in Non-Obese Women with and Without Polycystic Ovary Syndrome. International Journal of Molecular Sciences, 26(7), Article 3008. https://doi.org/10.3390/ijms26073008

Complement proteins are increased in polycystic ovary syndrome (PCOS), as are markers of inflammation, such as the C-reactive protein (CRP); however, both may be increased in obesity. We hypothesised that body mass index (BMI)-driven CRP would compar... Read More about Association of Complement Proteins with C Reactive Protein in Non-Obese Women with and Without Polycystic Ovary Syndrome.

Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia (2025)
Journal Article
Tantoush, F., Allsup, D., Naylor-Adamson, L., Voncken, F., & Caserta, S. (2025). Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia. Frontiers in immunology, 16, Article 1531059. https://doi.org/10.3389/fimmu.2025.1531059

Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor... Read More about Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.

Time, Tide, and Tempestuous Flooding: ‘To his Coy Mistress’ in an Age of Storms (2025)
Journal Article
Mottram, S., McDonagh, B., & Worthen, H. (online). Time, Tide, and Tempestuous Flooding: ‘To his Coy Mistress’ in an Age of Storms. Review of English Studies, https://doi.org/10.1093/res/hgaf012

Why might Marvell complain ‘by the tide | Of Humber’ in ‘To his Coy Mistress’? This article reads these lines in light of little-known records of flood risk management, housed at East Riding of Yorkshire Archives, Beverley, to uncover a new approach... Read More about Time, Tide, and Tempestuous Flooding: ‘To his Coy Mistress’ in an Age of Storms.

Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage (2025)
Journal Article
Smallwood, M. J., Alghayth, M. A., Knight, A. R., Tveen-Jensen, K., Pitt, A. R., Spickett, C. M., Llewellyn, D., Pula, G., Wearn, A., Vanhatalo, A., Jones, A. M., Francis, P., Coulthard, E., Kehoe, P. G., & Winyard, P. G. (2025). Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage. Redox Biology, 82, Article 103612. https://doi.org/10.1016/j.redox.2025.103612

Brain inflammation in Alzheimer's disease (AD) involves reactive nitrogen species (RNS) generation. Protein contents of 3-nitrotyrosine, a product of RNS generation, were assessed in frontal lobe brain homogenates from patients with AD, patients with... Read More about Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage.

Coordination chemistry of the calix[6]arene system: application in polymerisation catalysis and beyond (2025)
Journal Article
Redshaw, C. (in press). Coordination chemistry of the calix[6]arene system: application in polymerisation catalysis and beyond. Dalton Transactions : an international journal of inorganic chemistry, https://doi.org/10.1039/d5dt00473j

This perspective looks at structurally characterized examples of metal-based calix[6]arene complexes, focusing on the coordination chemistry adopted and their applications, primarily in polymerisation catalysis. In particular, we look at our attempts... Read More about Coordination chemistry of the calix[6]arene system: application in polymerisation catalysis and beyond.

Stock mispricing, corporate governance and SEOs market timing (2025)
Journal Article
Kumpamool, C., Guney, Y., & Hudson, R. S. (in press). Stock mispricing, corporate governance and SEOs market timing. International Journal of Managerial Finance, https://doi.org/10.1108/IJMF-06-2024-0356

Purpose: This paper examines the presence of stock market timing in Thailand. We explore the potential impact that equity overpricing, stock ownership and corporate board structure have on equity market timing. Design/methodology/approach: We use a c... Read More about Stock mispricing, corporate governance and SEOs market timing.

A Performance Modeling Study for Zero Fossil CO2 Stack Operation and Solvent Thermal Reclaiming in Post-Combustion Capture Industrial Applications (2025)
Journal Article
Michailos, S., Lucquiaud, M., Benz, A. D., Mullen, D., Elliott, W., & Gibbins, J. (2025). A Performance Modeling Study for Zero Fossil CO2 Stack Operation and Solvent Thermal Reclaiming in Post-Combustion Capture Industrial Applications. Industrial & engineering chemistry research, 64(13), 7100–7114. https://doi.org/10.1021/acs.iecr.4c04530

Post-combustion capture (PCC) of CO2 is widely recognized as the most mature technology to mitigate CO2 emissions from existing fossil fuel-based power plants and industrial sources, and successful deployment will predominantly rely on the ability of... Read More about A Performance Modeling Study for Zero Fossil CO2 Stack Operation and Solvent Thermal Reclaiming in Post-Combustion Capture Industrial Applications.

Employee ownership and workplace democracy: Antidotes to labour market monopsony? (2025)
Journal Article
FitzRoy, F. R., & Nolan, M. A. (in press). Employee ownership and workplace democracy: Antidotes to labour market monopsony?. Journal of Participation and Employee Ownership, https://doi.org/10.1108/JPEO-10-2022-0021

Purpose: We show that employee ownership is more efficient than control by external capital owners/employers. This complements the empirical evidence for benefits of employee ownership surveyed by Mygind and Poulsen (2021), Kruse (2022) and Dow (2003... Read More about Employee ownership and workplace democracy: Antidotes to labour market monopsony?.

Awareness and Understanding of Climate Change for Environmental Sustainability Using a Mix-Method Approach: A Study in the Kathmandu Valley (2025)
Journal Article
Shrestha, R., Kadel, R., Shakya, S., Nyachhyon, N., & Mishra, B. K. (2025). Awareness and Understanding of Climate Change for Environmental Sustainability Using a Mix-Method Approach: A Study in the Kathmandu Valley. Sustainability, 17(7), Article 2819. https://doi.org/10.3390/su17072819

Climate change is a global phenomenon having wide-ranging social, economic, ecological, and environmental sustainability implications. This study assesses climate change awareness, understanding, causes, mitigation measures, and practices among resid... Read More about Awareness and Understanding of Climate Change for Environmental Sustainability Using a Mix-Method Approach: A Study in the Kathmandu Valley.

A comprehensive process modelling, techno-economic and life cycle assessment of a power to ammonia process (2025)
Journal Article
Cuevas-Castillo, G. A., Michailos, S., Hughes, K., Ingham, D., & Pourkashanian, M. (2025). A comprehensive process modelling, techno-economic and life cycle assessment of a power to ammonia process. Sustainable Energy Technologies and Assessments an international journal, 76, Article 104278. https://doi.org/10.1016/j.seta.2025.104278

Ammonia is currently produced through H2 derived from fossil sources and hereby alternative low carbon ammonia routes are essential for mitigating emissions. The present study for the first time investigates the feasibility of the whole supply chain... Read More about A comprehensive process modelling, techno-economic and life cycle assessment of a power to ammonia process.

Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial (2025)
Journal Article
Crooks, M. G., Wright, C., Hart, S., Allgar, V., English, A., Swan, F., Dyson, J., Richardson, G., Twiddy, M., Cohen, J., Simpson, A., Huang, C., Sykes, D. L., & Johnson, M. (2025). Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial. BMJ Open Respiratory Research, 12(1), Article e002327. https://doi.org/10.1136/bmjresp-2024-002327

Introduction Breathlessness is common and impairs the quality of life of people with idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic interstitial lung diseases (ILD). We report the findings of a multicentre, fast-track (wait-list), mixed-met... Read More about Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial.

Social determinants of where people die: A study of moderators and mediators using linked UK Census and mortality data (2025)
Journal Article
Davies, J. M., Chua, K. C., Maddocks, M., Murtagh, F. E., & Sleeman, K. E. (2025). Social determinants of where people die: A study of moderators and mediators using linked UK Census and mortality data. SSM - Population Health, 30, Article 101784. https://doi.org/10.1016/j.ssmph.2025.101784

Background: Where people die depends on many factors and is important to the quality of end-of-life care. Many people prefer to avoid end-of-life hospital admissions and yet hospital remains the most common place of death across high-income countries... Read More about Social determinants of where people die: A study of moderators and mediators using linked UK Census and mortality data.

Spatial and temporal heterogeneity of the marine nitrogen cycle during the end-Triassic mass extinction (2025)
Journal Article
Li, J., Song, H., Du, Y., Wignall, P. B., Bond, D. P., Grasby, S. E., Song, H., Dal Corso, J., Tian, L., & Chu, D. (2025). Spatial and temporal heterogeneity of the marine nitrogen cycle during the end-Triassic mass extinction. Chemical Geology, 682, Article 122752. https://doi.org/10.1016/j.chemgeo.2025.122752

The end-Triassic mass extinction (ETME) marks a pivotal event in Earth's history, characterized by major environmental changes in both marine and terrestrial settings and significant perturbations in the carbon and nitrogen biogeochemical cycles alon... Read More about Spatial and temporal heterogeneity of the marine nitrogen cycle during the end-Triassic mass extinction.

Adaptive reconfigurable learning algorithm for robust optimal longitudinal motion control of UAVs (2025)
Journal Article
Saleem, O., Tanveer, A., & Iqbal, J. (2025). Adaptive reconfigurable learning algorithm for robust optimal longitudinal motion control of UAVs. Algorithms, 18(4), Article 180. https://doi.org/10.3390/a18040180

This study presents the formulation and verification of a novel online adaptive reconfigu-rable learning control algorithm (RLCA) for improved longitudinal motion control and disturbance compensation in unmanned aerial vehicles (UAVs). The proposed a... Read More about Adaptive reconfigurable learning algorithm for robust optimal longitudinal motion control of UAVs.

A qualitative study to understand the challenges of conducting randomised controlled trials of complex interventions in metastatic colorectal cancer (2025)
Journal Article
McKigney, N., Seligmann, J., Twiddy, M., Bach, S., Mohamed, F., Fearnhead, N., Brown, J., & Harji, D. (2025). A qualitative study to understand the challenges of conducting randomised controlled trials of complex interventions in metastatic colorectal cancer. Trials, 26(1), Article 98. https://doi.org/10.1186/s13063-025-08811-z

Background: The use of interventions such as major liver and lung resection, radiofrequency ablation and transarterial chemoembolization in the management of metastatic colorectal cancer (mCRC) is now relatively commonplace in clinical practice. Howe... Read More about A qualitative study to understand the challenges of conducting randomised controlled trials of complex interventions in metastatic colorectal cancer.

Spatial-spectral morphological mamba for hyperspectral image classification (2025)
Journal Article
Ahmad, M., Butt, M. H. F., Khan, A. M., Mazzara, M., Distefano, S., Usama, M., Roy, S. K., Chanussot, J., & Hong, D. (online). Spatial-spectral morphological mamba for hyperspectral image classification. Neurocomputing, Article 129995. https://doi.org/10.1016/j.neucom.2025.129995

Recent advancements in transformers, specifically self-attention mechanisms, have significantly improved hyperspectral image (HSI) classification. However, these models often have inefficiencies, as their computational complexity scales quadratically... Read More about Spatial-spectral morphological mamba for hyperspectral image classification.