All Outputs (16)

The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation (2020)
Thesis
Stinson, R. J. (2020). The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222863

Human Rhinovirus (hRV) is a major cause of upper respiratory tract infections (URTIs) and is linked to lower respiratory tract infections (LRTIs) and airway diseases exacerbations. Cough, airway inflammation and hypersensation are common symptoms of... Read More about The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation.

Positron emision [i.e. emission] tomography (PET) in non-malignant chest diseases (2019)
Thesis
Aliyu, S. A. (2019). Positron emision [i.e. emission] tomography (PET) in non-malignant chest diseases. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222034

Molecular imaging is a functional imaging that identify disease in its earliest stages and determine the exact location of metabolically active tissue such as tumours. Often before symptoms occur or abnormalities can be detected with other diagnostic... Read More about Positron emision [i.e. emission] tomography (PET) in non-malignant chest diseases.

The effect of human rhinovirus-16 on thermo-TRP channels, hypotonic activation and ATP release (2019)
Thesis
Atkinson, S. K. (2019). The effect of human rhinovirus-16 on thermo-TRP channels, hypotonic activation and ATP release. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4221658

Human rhinovirus (RV-16) infections are major cause of upper respiratory tract infections (URTI) and are associated with acute exacerbations of asthma and COPD. URTIs are associated with excessive production of mucus within the airway, particularly i... Read More about The effect of human rhinovirus-16 on thermo-TRP channels, hypotonic activation and ATP release.

Diagnostic confusion through the ages (2018)
Book Chapter
Morice, A. H. (2018). Diagnostic confusion through the ages. In A. H. Morice, & P. W. Dettmar (Eds.), Reflux Aspiration and Lung Disease (3-8). Springer. https://doi.org/10.1007/978-3-319-90525-9_1

Reflux aspiration and lung disease (2018)
Book
Morice, A. H., & Dettmar, P. W. (Eds.). (2018). Reflux aspiration and lung disease. Cham: Springer. https://doi.org/10.1007/978-3-319-90525-9

© Springer International Publishing AG, part of Springer Nature 2018. This book is about the interface between reflux and the respiratory tract. Reflux is an important factor in many different lung diseases. The pathological basis of reflux has recen... Read More about Reflux aspiration and lung disease.

An investigation into the mechanism of inhalational cough challenge (2018)
Thesis
Fowles, H. E. (2018). An investigation into the mechanism of inhalational cough challenge. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4220805

Chronic cough is a common problem. Historically treatments have focussed on treating underlying physiological causes. More recently an overarching theory of cough hypersensitivity syndrome has developed. In-vitro models of cough have not successfully... Read More about An investigation into the mechanism of inhalational cough challenge.

The emerging role of the eosinophil and its measurement in chronic cough : airway inflammation in chronic cough (2017)
Thesis
Haji Sadeghi, M. (2017). The emerging role of the eosinophil and its measurement in chronic cough : airway inflammation in chronic cough. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4220810

Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastro-oesophageal reflux disease, and upper airways disease, the inflammatory mechanisms underlying these conditions differ. Recent studies on a... Read More about The emerging role of the eosinophil and its measurement in chronic cough : airway inflammation in chronic cough.

The differential in vitro effects of clinically used vasoactive drugs on small human pulmonary vessels (2017)
Thesis
Hussain, A. (2017). The differential in vitro effects of clinically used vasoactive drugs on small human pulmonary vessels. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219718

Introduction:
Pulmonary hypertension (PH) is an important prognostic factor in cardiac surgery and is associated with increased morbidity and mortality. The mechanism of the underlying pathophysiology is complex and PH may exist prior to surgery or... Read More about The differential in vitro effects of clinically used vasoactive drugs on small human pulmonary vessels.

The effects of hydrogen sulfide on HEK-293 cells and human primary bronchial fibroblasts (2015)
Thesis
Kaura, V. (2015). The effects of hydrogen sulfide on HEK-293 cells and human primary bronchial fibroblasts. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218567

Hydrogen sulfide (H2S) is a key biologically relevant signalling molecule and has been recognised as the third endogenous gasotransmitter. H2S modulates various biological functions through complex mechanisms which may involve Transient Receptor Pote... Read More about The effects of hydrogen sulfide on HEK-293 cells and human primary bronchial fibroblasts.

The effect of oxygen, temperature and hydrogen sulphide on the human pulmonary circulation (2014)
Thesis
Ariyaratnam, P. (2014). The effect of oxygen, temperature and hydrogen sulphide on the human pulmonary circulation. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4215996

Introduction: The human pulmonary circulation is poorly understood at a physiological level which is a shame given that the pathology affecting it, particularly pulmonary artery hypertension, can have detrimental effects not only in the lungs but on... Read More about The effect of oxygen, temperature and hydrogen sulphide on the human pulmonary circulation.

The role of lipid laden macrophages in airways disease (2012)
Thesis
Hayman, Y. A. (2012). The role of lipid laden macrophages in airways disease. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214940

Asthma is a chronic inflammatory disease of the airway and is often associated with Gastro-Oesophageal Reflux (GOR). Lipid laden macrophages (LLM) in the airway have previously been reported indicative of aspiration secondary to GOR. We hypothesised... Read More about The role of lipid laden macrophages in airways disease.

The pathogenesis of idiopathic pulmonary fibrosis (2011)
Thesis
Fahim, A. (2011). The pathogenesis of idiopathic pulmonary fibrosis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4211904

Idiopathic pulmonary fibrosis (IPF) is a restrictive pulmonary disorder of unknown aetiology with a relentless disease course and a median survival of 3 years after the diagnosis. It is the most common idiopathic interstitial lung disease (ILD) with... Read More about The pathogenesis of idiopathic pulmonary fibrosis.

The role of n-linked glycosylation and sialylation in regulating human proteinase-activated receptor 1 and 4 expression and signalling (2008)
Thesis
Xiao, Y. P. (2008). The role of n-linked glycosylation and sialylation in regulating human proteinase-activated receptor 1 and 4 expression and signalling. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4208901

Proteinase-activated receptors (PARs) are a novel family of G-protein coupled receptors (GPCRs) that mediate many of the diverse biological effects of proteinases on target cells. N-linked glycosylation is a common post-translational modification in... Read More about The role of n-linked glycosylation and sialylation in regulating human proteinase-activated receptor 1 and 4 expression and signalling.

Diagnosis and treatment in airway inflammation (2007)
Thesis
Mulrennan, S. A. (2007). Diagnosis and treatment in airway inflammation. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223392

The design and development of a system for automatic sound analysis (2006)
Thesis
Barry, S. J. (2006). The design and development of a system for automatic sound analysis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224621

Cough monitoring has been undertaken for many years but the subsequent analysis of cough frequency and the temporal relation to trigger factors have proven problematic. Since cough is episodic, data collection over many hours is required; real-time a... Read More about The design and development of a system for automatic sound analysis.

Acute and chronic cough (2005)
Book
(2005). A. E. Redington, & A. H. Morice (Eds.), Acute and chronic cough. Boca Raton, Fla.: CRC Press. https://doi.org/10.1201/b14188

© 2005 by Taylor & Francis Group, LLC. A comprehensive review of the scientific and clinical aspects of acute and chronic cough, this reference focuses on recent developments in our understanding of the molecular biology of putative cough receptors... Read More about Acute and chronic cough.