All Outputs (46)

Ocean acidification affects marine chemical communication by changing structure and function of peptide signalling molecules (2016)
Journal Article
Roggatz, C. C., Lorch, M., Hardege, J. D., & Benoit, D. M. (2016). Ocean acidification affects marine chemical communication by changing structure and function of peptide signalling molecules. Global change biology, 22(12), 3914-3926. https://doi.org/10.1111/gcb.13354

Ocean acidification is a global challenge that faces marine organisms in the near future with a predicted rapid drop in pH of up to 0.4 units by the end of this century. Effects of the change in ocean carbon chemistry and pH on the development, growt... Read More about Ocean acidification affects marine chemical communication by changing structure and function of peptide signalling molecules.

Seizure control by decanoic acid through direct AMPA receptor inhibition (2015)
Journal Article
Chang, P., Augustin, K., Boddum, K., Williams, S., Sun, M., Terschak, J. A., …Williams, R. S. (2016). Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain, 139(2), 431-443. https://doi.org/10.1093/brain/awv325

The medium chain triglyceride ketogenic diet is an established treatment for drug-resistant epilepsy that increases plasma levels of decanoic acid and ketones. Recently, decanoic acid has been shown to provide seizure control in vivo, yet its mechani... Read More about Seizure control by decanoic acid through direct AMPA receptor inhibition.

Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii (2015)
Journal Article
Wäge, J., Lerebours, A., Hardege, J. D., & Rotchell, J. M. (2016). Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii. Ecotoxicology and environmental safety, 124(February), 105-110. https://doi.org/10.1016/j.ecoenv.2015.10.008

© 2015 Elsevier Inc. Fossil fuel emissions and changes in net land use lead to an increase in atmospheric CO 2 concentration and a subsequent decrease of ocean pH. Noticeable effects on organisms' calcification rate, shell structure and energy metabo... Read More about Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii.

Oxidized mild steel S235: an efficient anode for the electrocatalytically initiated water-splitting (2015)
Journal Article
Schäfer, H., Küpper, K., Wollschläger, J., Kashaev, N., Hardege, J., Walder, L., …Dorn, F. (2015). Oxidized mild steel S235: an efficient anode for the electrocatalytically initiated water-splitting. ChemSusChem, 8(18), 3099-3110. https://doi.org/10.1002/cssc.201500666

The surface of steel S235 was oxidized by Cl₂ gas and checked for its electrocatalytic efficiency regarding oxygen formation in aqueous solution. If exposed to humid Cl₂ gas for 110 min, steel S235 became an electrocatalyst that exhibits an overpoten... Read More about Oxidized mild steel S235: an efficient anode for the electrocatalytically initiated water-splitting.

Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics (2015)
Journal Article
Schäfer, H., Sadaf, S., Walder, L., Kuepper, K., Dinklage, S., Wollschläger, J., …Daum, D. (2015). Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics. Energy & environmental science, 8(9), 2685-2697. https://doi.org/10.1039/c5ee01601k

The oxygen evolution reaction (OER) is known as the efficiency-limiting step for the electrochemical cleavage of water mainly due to the large overpotentials commonly used materials on the anode side cause. Since Ni–Fe oxides reduce overpotentials oc... Read More about Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics.

Effects of low seawater pH on the marine polychaete Platynereis dumerilii (2015)
Journal Article
Wäge, J., Hardege, J. D., Larsson, T. A., Simakov, O., Chapman, E. C., Arendt, D., & Rotchell, J. M. (2015). Effects of low seawater pH on the marine polychaete Platynereis dumerilii. Marine pollution bulletin, 95(1), 166-172. https://doi.org/10.1016/j.marpolbul.2015.04.027

An important priority for any organism is to maintain internal cellular homeostasis including acidbase balance. Yet, the molecular level impacts of changing environmental conditions, such as low pH, remain uncharacterised. Herein, we isolate partial... Read More about Effects of low seawater pH on the marine polychaete Platynereis dumerilii.

Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO₂ vent system (2013)
Journal Article
Calosi, P., Rastrick, S. P., Lombardi, C., de Guzman, H. J., Davidson, L., Jahnke, M., …Gambi, M. C. (2013). Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO₂ vent system. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1627), 0-0. https://doi.org/10.1098/rstb.2012.0444

Metabolic rate determines the physiological and life-history performances of ectotherms. Thus, the extent to which such rates are sensitive and plastic to environmental perturbation is central to an organism's ability to function in a changing enviro... Read More about Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO₂ vent system.

Divergence of scent pheromones in allopatric populations of Acanthodactylus boskianus (Squamata: Lacertidae) (2013)
Journal Article
Khannoon, E. R., Lunt, D. H., Schulz, S., & Hardege, J. (2013). Divergence of scent pheromones in allopatric populations of Acanthodactylus boskianus (Squamata: Lacertidae). Zoological Science, 30(5), 380-385. https://doi.org/10.2108/zsj.30.380

The evolutionary phenomena associated with divergence in chemical signals between populations of the same species help to understand the process of speciation. Animals detect and react to semiochemicals and pheromones used in communication. Compariso... Read More about Divergence of scent pheromones in allopatric populations of Acanthodactylus boskianus (Squamata: Lacertidae).

Identification of a female sex pheromone in Carcinus maenas (2011)
Journal Article
Hardege, J. D., Bartels-Hardege, H. D., Fletcher, N., Terschak, J. A., Harley, M., Smith, M. A., …Bublitz, R. (2011). Identification of a female sex pheromone in Carcinus maenas. Marine ecology progress series, 436, 177-189. https://doi.org/10.3354/meps09226

Despite major progress in our understanding of animal signaling systems, the identification of chemical signals in aquatic organisms is still in its infancy. Exemplary for this is the lack of structural knowledge of crustacean sex pheromones despite... Read More about Identification of a female sex pheromone in Carcinus maenas.

Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification (2011)
Journal Article
Hardege, J., Rotchell, J., Terschak, J., & Greenway, G. (2011). Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification. Trends in Analytical Chemistry, 30(8), 1320-1326. https://doi.org/10.1016/j.trac.2011.07.004

Changing ocean-carbonate chemistry caused by oceanic uptake of anthropogenic atmospheric carbon dioxide leads to the formation of carbonic acid, thus lowering the pH of the sea with predictions of a decrease from current levels at 8.15 to 7.82 by the... Read More about Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification.

Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones (2011)
Journal Article
Hardege, J. D., Harley, M. A., Lin, J., Terschak, J. A., & Zhang, D. (2011). Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones. PLoS ONE, 6(4), e17720. https://doi.org/10.1371/journal.pone.0017720

Successful mating is essentially a consequence of making the right choices at the correct time. Animals use specific strategies to gain information about a potential mate, which is then applied to decision-making processes. Amongst the many informati... Read More about Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones.

The fecal odor of sick hedgehogs (Erinaceus europaeus) mediates olfactory attraction of the tick Ixodes hexagonus (2011)
Journal Article
Bunnell, T., Hanisch, K., Hardege, J. D., & Breithaupt, T. (2011). The fecal odor of sick hedgehogs (Erinaceus europaeus) mediates olfactory attraction of the tick Ixodes hexagonus. Journal of Chemical Ecology, 37(4), 340-347. https://doi.org/10.1007/s10886-011-9936-1

Parasite loads of animals vary among individuals, but the underlying mechanisms have not been fully identified. Here, we investigated whether health status of hedgehogs (Erinaceus europaeus) is correlated with tick burden, and whether chemical cues l... Read More about The fecal odor of sick hedgehogs (Erinaceus europaeus) mediates olfactory attraction of the tick Ixodes hexagonus.

New compounds, sexual differences, and age-related variations in the femoral gland secretions of the lacertid lizard Acanthodactylus boskianus (2011)
Journal Article
Khannoon, E. R., Flachsbarth, B., El-Gendy, A., Mazik, K., Hardege, J. D., & Schulz, S. (2011). New compounds, sexual differences, and age-related variations in the femoral gland secretions of the lacertid lizard Acanthodactylus boskianus. Biochemical Systematics and Ecology, 39(2), 95-101. https://doi.org/10.1016/j.bse.2011.01.008

Integumental gland secretions in lizards have been postulated to play a role as semiochemicals, but few studies have analysed the chemical nature of the gland secretions used in communication. We analysed the femoral gland secretions of Acanthodactyl... Read More about New compounds, sexual differences, and age-related variations in the femoral gland secretions of the lacertid lizard Acanthodactylus boskianus.

Biological responses to contaminants in the Humber Estuary: disentangling complex relationships (2011)
Journal Article
García-Alonso, J., Greenway, G., Munshi, A., Gómez, J., Mazik, K., Knight, A. W., …Elliott, M. (2011). Biological responses to contaminants in the Humber Estuary: disentangling complex relationships. Marine environmental research, 71(4), 295-303. https://doi.org/10.1016/j.marenvres.2011.02.004

Due to the ecological importance of estuaries, it is necessary to understand the biological effects that potentially toxic contaminants induce in bioindicator species. A key aspect is whether effects at lower levels of biological organisation transfe... Read More about Biological responses to contaminants in the Humber Estuary: disentangling complex relationships.

Evidence that 1-methyl-L-tryptophan is a food-related odorant for the Senegalese sole (Solea senegalensis) (2011)
Journal Article
Velez, Z., Hubbard, P. C., Hardege, J. D., Welham, K. J., Barata, E. N., & Canário, A. V. M. (2011). Evidence that 1-methyl-L-tryptophan is a food-related odorant for the Senegalese sole (Solea senegalensis). Aquaculture, 314(1-4), 153-158. https://doi.org/10.1016/j.aquaculture.2011.01.025

Nocturnal animals often rely heavily on olfactory cues to locate their food. This is especially true for fish whose prey live buried in the substrate. The aim of the current study was to identify non-polar odorants released by the ragworm (Hediste di... Read More about Evidence that 1-methyl-L-tryptophan is a food-related odorant for the Senegalese sole (Solea senegalensis).

Microscreening toxicity system based on living magnetic yeast and gradient chips (2010)
Journal Article
García-Alonso, J., Fakhrullin, R. F., Paunov, V. N., Shen, Z., Hardege, J. D., Pamme, N., …Greenway, G. M. (2011). Microscreening toxicity system based on living magnetic yeast and gradient chips. Analytical and Bioanalytical Chemistry, 400(4), 1009-1013. https://doi.org/10.1007/s00216-010-4241-3

There is an increasing demand for easy and cost-effective methods to screen the toxicological impact of the growing number of chemical mixtures being generated by industry. Such a screening method has been developed using viable, genetically modified... Read More about Microscreening toxicity system based on living magnetic yeast and gradient chips.

Experience matters: Females use smell to select experienced males for paternal care (2009)
Journal Article
Fletcher, N., Storey, E. J., Johnson, M., Reish, D. J., & Hardege, J. D. (2009). Experience matters: Females use smell to select experienced males for paternal care. PLoS ONE, 4(11), e7672. https://doi.org/10.1371/journal.pone.0007672

Mate choice and mating preferences often rely on the information content of signals exchanged between potential partners. In species where a female's reproduction is the terminal event in life it is to be expected that females choose high quality mal... Read More about Experience matters: Females use smell to select experienced males for paternal care.

Characterization of a sex pheromone in a simultaneous hermaphroditic shrimp, Lysmata wurdemanni (2009)
Journal Article
Zhang, D., Lin, J., Harley, M., & Hardege, J. D. (2010). Characterization of a sex pheromone in a simultaneous hermaphroditic shrimp, Lysmata wurdemanni. Marine Biology, 157(1), 1-6. https://doi.org/10.1007/s00227-009-1290-2

Olfactory chemical cues have been described to play important roles in the control of mate recognition in many decapod crustaceans. However, we still know very little about the chemical characteristics of the cues that coordinate pre-copulative behav... Read More about Characterization of a sex pheromone in a simultaneous hermaphroditic shrimp, Lysmata wurdemanni.

Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis) (2009)
Journal Article
Velez, Z., Hubbard, P. C., Welham, K., Hardege, J., Barata, E. N., & Canário, A. V. M. (2009). Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis). Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 195(7), 691-698. https://doi.org/10.1007/s00359-009-0444-5

Olfactory sensitivity to bile salts is wide-spread in teleosts; however, which bile salts are released in sufficient quantities to be detected is unclear. The current study identified bile salts in the intestinal and bile fluids of Solea senegalensis... Read More about Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis).

The cost of conflict: agonistic encounters influence responses to chemical signals in the European shore crab (2008)
Journal Article
Fletcher, N., & Hardege, J. D. (2009). The cost of conflict: agonistic encounters influence responses to chemical signals in the European shore crab. Animal behaviour, 77(2), 357-361. https://doi.org/10.1016/j.anbehav.2008.10.007

The determination of an individual's behaviour often relies upon complex signals that convey messages about the environment it inhabits. In aquatic environments such signals take varied and conflicting forms including chemical cues indicating food or... Read More about The cost of conflict: agonistic encounters influence responses to chemical signals in the European shore crab.