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Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer (2012)
Journal Article
Hodgkinson, V. C., Agarwal, V., ElFadl, D., Fox, J. N., McManus, P. L., Mahapatra, T. K., …Cawkwell, L. (2012). Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer. Journal of Proteomics, 75(9), 2745-2752. https://doi.org/10.1016/j.jprot.2012.03.049

Neoadjuvant chemotherapy is used to treat oestrogen receptor-positive breast cancer however chemo-resistance is a major obstacle in this molecular subtype. The ability to predict tumour response would allow chemotherapy administration to be directed... Read More about Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer.

Synthesis, structure and photophysical properties of 2-benzhydryl-4-methyl- 6-(aryliminomethyl)phenol ligands and the zinc complexes thereof (2012)
Journal Article
Zhou, Z., Li, W., Hou, X., Chen, L., Hao, X., Redshaw, C., & Sun, W. H. (2012). Synthesis, structure and photophysical properties of 2-benzhydryl-4-methyl- 6-(aryliminomethyl)phenol ligands and the zinc complexes thereof. Inorganica Chimica Acta, 392, 292-299. https://doi.org/10.1016/j.ica.2012.03.046

The Schiff-base ligands 2-benzhydryl-4-methyl-6-((phenylimino)methyl)phenol (L1-L5), and their corresponding zinc complexes (C1-C5), were prepared and fully characterized. The UV-Vis absorption and fluorescence spectra of the ligands and their Zn(II)... Read More about Synthesis, structure and photophysical properties of 2-benzhydryl-4-methyl- 6-(aryliminomethyl)phenol ligands and the zinc complexes thereof.

Clinical update - prescribing in ophthalmology (2012)
Journal Article
Lee, A. (2012). Clinical update - prescribing in ophthalmology. International journal of ophthalmic practice, 3(2), 88 - 91. https://doi.org/10.12968/ijop.2012.3.2.88

This is the second in a series of two articles discussing prescribing in advanced ophthalmic nursing practice in the UK. With the support of ophthalmic nurse practitioners this article explores issues relating to medicines management, the patient's e... Read More about Clinical update - prescribing in ophthalmology.

Public procurement in the EU: jurisprudence and conceptual directions (2012)
Journal Article
Bovis, C. H. (2012). Public procurement in the EU: jurisprudence and conceptual directions. Common Market Law Review, 49(1), 247-290

The present article reviews the emerging conceptual themes from the case law of the European Court of Justice which have triggered the revision of the public procurement Directives, and the alignment of the public procurement acquis with the Europe 2... Read More about Public procurement in the EU: jurisprudence and conceptual directions.

Alert rules for remote monitoring of cardiovascular patients (2012)
Journal Article
Bohacik, J., & Davis, D. (2012). Alert rules for remote monitoring of cardiovascular patients. Journal of information technologies, 5(1), 16 - 23

Cardiovascular disease is the leading cause of death in most European countries and its prevention requires major life-style changes using limited health-care resources. Remote cardiovascular decision support seems to allow cardiovascular patients to... Read More about Alert rules for remote monitoring of cardiovascular patients.

Comparative time series analysis of perceptual responses to electroacoustic music (2012)
Journal Article
Bailes, F., & Dean, R. T. (2012). Comparative time series analysis of perceptual responses to electroacoustic music. Music Perception, 29(4), 359-375. https://doi.org/10.1525/mp.2012.29.4.359

This study investigates the relationship between acoustic patterns in contemporary electroacoustic compositions, and listeners’ real-time perceptions of their structure and affective content. Thirty-two participants varying in musical expertise (nonm... Read More about Comparative time series analysis of perceptual responses to electroacoustic music.

Longitudinal trajectories of awareness in early-stage dementia (2012)
Journal Article
Clare, L., Nelis, S. M., Martyr, A., Whitaker, C. J., Marková, I. S., Roth, I., …Morris, R. G. (2012). Longitudinal trajectories of awareness in early-stage dementia. Alzheimer Disease and Associated Disorders, 26(2), 140-147. https://doi.org/10.1097/WAD.0b013e31822c55c4

Although it is often assumed that awareness decreases as dementia severity increases, there is limited evidence regarding changes in awareness over time. We examined awareness in 101 individuals with early-stage dementia (PwD) and their carers; 66 we... Read More about Longitudinal trajectories of awareness in early-stage dementia.

Marital relationship quality in early-stage dementia: Perspectives from people with dementia and their spouses (2012)
Journal Article
Martyr, A., Clare, L., Nelis, S. M., Markova, I. S., Roth, I., Woods, R. T., …Morris, R. G. (2012). Marital relationship quality in early-stage dementia: Perspectives from people with dementia and their spouses. Alzheimer Disease and Associated Disorders, 26(2), 148-158. https://doi.org/10.1097/WAD.0b013e318221ba23

Spouse caregivers of people with dementia (PwD) report relatively poor marital relationship quality (RQ), but few studies have obtained the perspective of the PwD, examined discrepancies between spouses, or considered changes in RQ over time. This st... Read More about Marital relationship quality in early-stage dementia: Perspectives from people with dementia and their spouses.

Verbal fluency and awareness of functional deficits in early-stage dementia (2012)
Journal Article
Marková, I. S., Woods, R. T., Whitaker, C. J., Markova, I., Clare, L., Martyr, A., …Woods, R. (2012). Verbal fluency and awareness of functional deficits in early-stage dementia. Clinical Neuropsychologist, 26(3), 501-519. https://doi.org/10.1080/13854046.2012.665482

Assessment of activities of daily living is an important element in the diagnosis of dementia, with research suggesting a link between functional ability and cognition. We investigated the relationship between self- and informant ratings of instrumen... Read More about Verbal fluency and awareness of functional deficits in early-stage dementia.

Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites (2012)
Journal Article
Ghumra, A., Semblat, J. P., Ataide, R., Kifude, C., Adams, Y., Claessens, A., …Rowe, J. A. (2012). Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites. PLoS Pathogens, 8(4), Article e1002665. https://doi.org/10.1371/journal.ppat.1002665

Sequence diversity in pathogen antigens is an obstacle to the development of interventions against many infectious diseases. In malaria caused by Plasmodium falciparum, the PfEMP1 family of variant surface antigens encoded by var genes are adhesion m... Read More about Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites.

Identifying and acting on early warning signs in complex projects (2012)
Journal Article
Williams, T., Jonny Klakegg, O., Walker, D. H., Andersen, B., & Morten Magnussen, O. (2012). Identifying and acting on early warning signs in complex projects. Project management journal, 43(2), 37-53. https://doi.org/10.1002/pmj.21259

We consider identification of early warning signs (EWS) in projects. Project professionals are not good at detecting or acting on EWS. Barriers that lead to this are identified. The nature of EWS and their detection change with the evolving situation... Read More about Identifying and acting on early warning signs in complex projects.

Queen Caroline’s pains and penalties: Silence and speech in the dramatic art of British women’s suffrage (2012)
Journal Article
Cockin, K. (2012). Queen Caroline’s pains and penalties: Silence and speech in the dramatic art of British women’s suffrage. Law and literature, 24(1), 40-58. https://doi.org/10.1525/lal.2012.24.1.40

In Britain, the act that launched the militant campaign of the suffragettes in 1905 was the interruption of a political meeting in Manchester. The violent silencing and arrest of the women ensued. The women’s suffrage campaigns in Britain became more... Read More about Queen Caroline’s pains and penalties: Silence and speech in the dramatic art of British women’s suffrage.

Two CYP3A-like genes in the marine mussel Mytilus edulis: mRNA expression modulation following short-term exposure to endocrine disruptors (2012)
Journal Article
Cubero-Leon, E., Puinean, A. M., Labadie, P., Ciocan, C., Itoh, N., Kishida, M., …Rotchell, J. M. (2012). Two CYP3A-like genes in the marine mussel Mytilus edulis: mRNA expression modulation following short-term exposure to endocrine disruptors. Marine environmental research, 74, 32-39. https://doi.org/10.1016/j.marenvres.2011.11.012

Members of the vertebrate CYP3A subfamily are involved in the metabolism of steroids and a wide range of xenobiotics. In this study two CYP3A- like mRNAs have been isolated from the mussel (Mytilus edulis), and their seasonal expression profile and m... Read More about Two CYP3A-like genes in the marine mussel Mytilus edulis: mRNA expression modulation following short-term exposure to endocrine disruptors.

Dissociating positive and negative influences of verbal processing on the recognition of pictures of faces and objects (2012)
Journal Article
Nakabayashi, K., Burton, A. M., Brandimonte, M. A., & Lloyd-Jones, T. J. (2012). Dissociating positive and negative influences of verbal processing on the recognition of pictures of faces and objects. Journal of Experimental Psychology: Learning, Memory, and Cognition, 38(2), 376-390. https://doi.org/10.1037/a0025782

Four experiments investigated the role of verbal processing in the recognition of pictures of faces and objects. We used (a) a stimulus-encoding task where participants learned sequentially presented pictures in control, articulatory suppression, and... Read More about Dissociating positive and negative influences of verbal processing on the recognition of pictures of faces and objects.