Skip to main content

Research Repository

Advanced Search

All Outputs (82)

Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer (2021)
Thesis
McKenzie, G. A. G. (2021). Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer. (Thesis). The University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4192792

Introduction: Older adults with cancer have worse outcomes than their younger counterparts, including higher postoperative complications, chemotherapy toxicity and treatment allocation to best supportive care. Oncogeriatric assessment (OGA) can provi... Read More about Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer.

Renewing approaches to understanding the minerals and waters at alkaline waste sites (2021)
Thesis
Bastianini, L. (2021). Renewing approaches to understanding the minerals and waters at alkaline waste sites. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224152

Highly alkaline (pH 9-12) waters can arise from a range of natural and anthropogenic processes. The latter include drainage waters from a range of globally significant anthropogenic by-products such as lime, cement and steel wastes, bauxite processin... Read More about Renewing approaches to understanding the minerals and waters at alkaline waste sites.

New routes to chiral-at-metal organometallic complexes and their application in asymmetric synthesis (2021)
Thesis
Shroot, S. (2021). New routes to chiral-at-metal organometallic complexes and their application in asymmetric synthesis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224096

This project develops new organometallic frameworks, to target the asymmetric transfer hydrogenation and hydrosilylation of ketones, aiming for enhanced activity and substrate scope relative to current state-of-the-art. The anticancer activity of som... Read More about New routes to chiral-at-metal organometallic complexes and their application in asymmetric synthesis.

Investigation of graphene oxide-based composite material strategies as possible candidates for leading edge erosion protection of offshore wind turbines (2021)
Thesis
Glanville, L. B. L. (2021). Investigation of graphene oxide-based composite material strategies as possible candidates for leading edge erosion protection of offshore wind turbines. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224240

At present the current climate and energy crisis has highlighted the global need for more renewable energy generation. Offshore wind provides a reliable source of this green energy however the harsh environments these assets operate in result in freq... Read More about Investigation of graphene oxide-based composite material strategies as possible candidates for leading edge erosion protection of offshore wind turbines.

Lab-on-a-chip platforms for pathogen analysis (2021)
Thesis
Rodriguez Mateos, P. (2021). Lab-on-a-chip platforms for pathogen analysis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224144

Infectious diseases caused by pathogenic microorganisms are a big burden in developed and developing countries. The emergence and rapid global spread of virus and antimicrobial resistant bacteria is a significant threat to patients, healthcare system... Read More about Lab-on-a-chip platforms for pathogen analysis.

Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia (2021)
Thesis
Naylor-Adamson, L. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4224129

Ibrutinib is highly effective in the treatment of chronic lymphocytic leukaemia (CLL), disrupting B cell receptor signalling through the inhibition of Bruton’s tyrosine kinase (Btk). However, ibrutinib has off-target effects, inhibiting platelet aggr... Read More about Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia.

Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor (2021)
Thesis
Plater, J. (2021). Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223832

The chemokine receptor CXCR4 has been shown to be over-expressed in multiple cancer types and is often linked to a poor prognosis, making it a significant target of interest for both imaging and therapeutics. Early diagnosis, imaging and identificati... Read More about Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor.

Evidence of herding behaviour in stock markets (2021)
Thesis
Wang, J. (2021). Evidence of herding behaviour in stock markets. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224272

This thesis investigates herding behaviour among major world stock markets from 2002 to 2018. It also studies the herding behaviour at sector level from 2001 to 2020. In the first chapter, we introduce the background and motivation for this study. In... Read More about Evidence of herding behaviour in stock markets.

Yorkshire’s folk culture in digital spaces during the COVID-19 pandemic : cultural practice, digitalisation and localisation (2021)
Thesis
Sewell, C. T. (2021). Yorkshire’s folk culture in digital spaces during the COVID-19 pandemic : cultural practice, digitalisation and localisation. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224009

This thesis critically assesses the digital spaces where Yorkshire’s folk community practiced sonic and material cultures and developed identities of communal belonging during the initial phase of the COVID-19 pandemic. Using data gathered throughout... Read More about Yorkshire’s folk culture in digital spaces during the COVID-19 pandemic : cultural practice, digitalisation and localisation.

Sporopollenin : applications in water purification (2021)
Thesis
Meichanetzoglou, A. (2021). Sporopollenin : applications in water purification. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223849

Water pollution from emerging contaminants is increasingly in the spotlight, as research on the impacts on the environment is revealing more about the dangers to both animals in the aquatic environment and human health. Pharmaceuticals, personal care... Read More about Sporopollenin : applications in water purification.

Mechanochemical ablation in the treatment of superficial venous incompetence (2021)
Thesis
Mohamed, A. (2021). Mechanochemical ablation in the treatment of superficial venous incompetence. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4223528

Background The routine management of venous incompetence has undergone considerable changes in the last two decades led by the introduction of minimally invasive endovenous techniques. At the heart of these changes has been a drive to offer patients... Read More about Mechanochemical ablation in the treatment of superficial venous incompetence.

Iron sulfide as a sustainable catalyst for the selective hydrogen transfer reduction for the synthesis of fine chemicals (2021)
Thesis
Southouse, J. P. (2021). Iron sulfide as a sustainable catalyst for the selective hydrogen transfer reduction for the synthesis of fine chemicals. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224438

Platinum group metals have been the most widely applied metals for hydrogenation catalysts used in the synthesis of fine chemicals; this has been due to their high catalytic activity and ease of preparation. However, platinum group metal-based cataly... Read More about Iron sulfide as a sustainable catalyst for the selective hydrogen transfer reduction for the synthesis of fine chemicals.

Investigation of the regulatory role of CBX2 in breast cancer via in silico transcriptomic analysis and in vitro cistromic analysis (2021)
Thesis
Kalsi, S. C. (2021). Investigation of the regulatory role of CBX2 in breast cancer via in silico transcriptomic analysis and in vitro cistromic analysis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224331

Chromobox 2 (CBX2) is a component of Polycomb repressive protein complex 1 (PRC1), which is an epigenetic regulatory complex that downregulates the expression of target genes. CBX2 has been linked to cancer progression and development in several canc... Read More about Investigation of the regulatory role of CBX2 in breast cancer via in silico transcriptomic analysis and in vitro cistromic analysis.

Quantitative morphology of galaxy clusters at X-ray wavelengths (2021)
Thesis
Hunt, L. (2021). Quantitative morphology of galaxy clusters at X-ray wavelengths. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224267

We apply quantitative morphology techniques to X-ray imaging of clusters of galaxies to determine correlation between calculated parameters (CAS, Gini and M20) and features such as bow shocks, cold fronts, gas sloshing, Kelvin-Helmholtz instabilities... Read More about Quantitative morphology of galaxy clusters at X-ray wavelengths.

Signatures of i-process nucleosynthesis (2021)
Thesis
Womack, K. A. (2021). Signatures of i-process nucleosynthesis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224179

Neutron capture nucleosynthesis is responsible for the production of heavy elements. Three neutron capture processes are currently known, each occurring at their own characteristic neutron density and operating in different ways. The slow neutron cap... Read More about Signatures of i-process nucleosynthesis.

Behaviour and spatial ecology of resident brown trout in Langsett reservoir and its tributaries with impassable weirs (2021)
Thesis
Owen, H. (2021). Behaviour and spatial ecology of resident brown trout in Langsett reservoir and its tributaries with impassable weirs. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224147

Anthropogenic alterations to river systems, such as the construction of dams and weirs, have significantly impacted fish populations globally by reducing connectivity to key life stage habitats. Langsett Reservoir, situated in south Yorkshire, holds... Read More about Behaviour and spatial ecology of resident brown trout in Langsett reservoir and its tributaries with impassable weirs.

The need for epistemic reciprocity in person-centred care : a multi-method qualitative study (2021)
Thesis
Dell’Olio, M. (2021). The need for epistemic reciprocity in person-centred care : a multi-method qualitative study. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4224117

Background – Person-centred care is a policy priority in the United Kingdom, yet people with long-term conditions report a deficiency in person-centred healthcare relative to their wishes and expectations. Whilst several factors contribute to this pr... Read More about The need for epistemic reciprocity in person-centred care : a multi-method qualitative study.

The blessings of explainable AI in operations & maintenance of wind turbines (2021)
Thesis
Chatterjee, J. (2021). The blessings of explainable AI in operations & maintenance of wind turbines. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223982

Wind turbines play an integral role in generating clean energy, but regularly suffer from operational inconsistencies and failures leading to unexpected downtimes and significant Operations & Maintenance (O&M) costs. Condition-Based Monitoring (CBM)... Read More about The blessings of explainable AI in operations & maintenance of wind turbines.