Brain haemosiderin in older people: Pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds

Janaway, B. M.; Simpson, J. E.; Hoggard, N.; Highley, J. R.; Forster, G.; Drew, D.; Gebril, O. H.; Matthews, F. E.; Brayne, C.; Wharton, S. B.; Ince, P. G.

doi:10.1111/nan.12062

Hierarchical reinforcement learning for situated natural language generation (2014)
Journal Article
Dethlefs, N., & Cuayáhuitl, H. (2015). Hierarchical reinforcement learning for situated natural language generation. Natural language engineering, 21(3), 391-435. https://doi.org/10.1017/S1351324913000375

Natural Language Generation systems in interactive settings often face a multitude of choices, given that the communicative effect of each utterance they generate depends crucially on the interplay between its physical circumstances, addressee and in... Read More about Hierarchical reinforcement learning for situated natural language generation.

Valley formation by groundwater seepage, pressurized groundwater outbursts and crater-lake overflow in flume experiments with implications for Mars (2014)
Journal Article
Marra, W. A., Braat, L., Baar, A. W., & Kleinhans, M. G. (2014). Valley formation by groundwater seepage, pressurized groundwater outbursts and crater-lake overflow in flume experiments with implications for Mars. Icarus, 232, 97-117. https://doi.org/10.1016/j.icarus.2013.12.026

Remains of fluvial valleys on Mars reveal the former presence of water on the surface. However, the source of water and the hydrological setting is not always clear, especially in types of valleys that are rare on Earth and where we have limited know... Read More about Valley formation by groundwater seepage, pressurized groundwater outbursts and crater-lake overflow in flume experiments with implications for Mars.

Experimental neutron capture data of 58 Ni from the CERN n-TOF facility (2014)
Journal Article
Žugec, P., Barbagallo, M., Colonna, N., Bosnar, D., Altstadt, S., Andrzejewski, J., Audouin, L., Bécares, V., Bečvář, F., Belloni, F., Berthoumieux, E., Billowes, J., Boccone, V., Brugger, M., Calviani, M., Calvino, F., Cano-Ott, D., Carrapiço, C., Cerutti, F., Chiaveri, E., …Wright, T. J. (2014). Experimental neutron capture data of 58 Ni from the CERN n-TOF facility. Physical Review C - Nuclear Physics, 89(1), 014605-1-014605-9. https://doi.org/10.1103/physrevc.89.014605

The ⁵⁸Ni(n,γ) cross section has been measured at the neutron time of flight facility n_TOF at CERN, in the energy range from 27 meV up to 400 keV. In total, 51 resonances have been analyzed up to 122 keV. Maxwellian averaged cross sections (MACS) hav... Read More about Experimental neutron capture data of 58 Ni from the CERN n-TOF facility.

The environmental dependence of neutral hydrogen in the GIMIC simulations (2014)
Journal Article
Cunnama, D., Andrianomena, S., Cress, C. M., Faltenbacher, A., Gibson, B. K., & Theuns, T. (2014). The environmental dependence of neutral hydrogen in the GIMIC simulations. Monthly notices of the Royal Astronomical Society, 438(3), 2530-2537. https://doi.org/10.1093/mnras/stt2380

We use the Galaxies-Intergalactic Medium Interaction Calculation (GIMIC) cosmological hydrodynamic simulation at z = 0 to study the distribution and environmental dependence of neutral hydrogen (H I) gas in the outskirts of simulated galaxies. This g... Read More about The environmental dependence of neutral hydrogen in the GIMIC simulations.

How typical is the Coma cluster? (2014)
Journal Article
Pimbblet, K. A., Penny, S. J., & Davies, R. L. (2014). How typical is the Coma cluster?. Monthly notices of the Royal Astronomical Society, 438(4), 3049-3057. https://doi.org/10.1093/mnras/stt2411

Coma is frequently used as the archetype z ∼ 0 galaxy cluster to compare higher redshift work against. It is not clear, however, how representative the Coma cluster is for galaxy clusters of its mass or X-ray luminosity, and significantly, recent wor... Read More about How typical is the Coma cluster?.

A Spectrum Sensing Test Bed based on Matlab and USRP2 (2014)
Presentation / Conference Contribution
Ammar, M., Mehdawi, M., Riley, N., Fanan, A., Paulson, K., & Zolfaghari, M. (2014, January). A Spectrum Sensing Test Bed based on Matlab and USRP2. Presented at International Conference on Machine Learning, Electrical and Mechanical Engineering

— The spectrum monitoring has gained new aspects with development of the software defined radio SDR as its very important issue in the spectrum management area. In this paper a spectrum monitoring technique with SDR is proposed, the setup of the prot... Read More about A Spectrum Sensing Test Bed based on Matlab and USRP2.

Bubbles, shocks and elementary technical trading strategies (2014)
Journal Article
Fry, J. (2014). Bubbles, shocks and elementary technical trading strategies. European Physical Journal B : Condensed Matter and Complex Systems, 87, Article 1. https://doi.org/10.1140/epjb/e2013-40587-y

In this paper we provide a unifying framework for a set of seemingly disparate models for bubbles, shocks and elementary technical trading strategies in financial markets. Markets operate by balancing intrinsic levels of risk and return. This seeming... Read More about Bubbles, shocks and elementary technical trading strategies.

Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis. (2014)
Journal Article
Fahim, A., Crooks, M. G., Morice, A. H., & Hart, S. P. (2014). Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis. Lung, 192(2), 277-284. https://doi.org/10.1007/s00408-013-9546-5

Purpose Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia and its prognosis is poor. Epidemiological evidence suggests an association of IPF with vascular disease and thrombotic tendency, which may be related to... Read More about Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis..

Psychological and educational interventions for atopic eczema in children (2014)
Journal Article
Flohr, C., Thompson, A. R., Drury, A., Cowdell, F., Ware, F., Farasat, H., Jackson, K., Thomas, P., Ersser, S. J., Latter, S., & Gardiner, E. (2014). Psychological and educational interventions for atopic eczema in children. Cochrane Database of Systematic Reviews, 2017(5), 0 - 0. https://doi.org/10.1002/14651858.CD004054.pub3

© 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Psychological and educational interventions have been used as an adjunct to conventional therapy for children with atopic eczema to enhance the effectiveness of top... Read More about Psychological and educational interventions for atopic eczema in children.

Teacher and student perceptions of the development of learner autonomy : a case study in the biological sciences (2014)
Journal Article
Scott, G. W., Furnell, J., Murphy, C. M., & Goulder, R. (2015). Teacher and student perceptions of the development of learner autonomy : a case study in the biological sciences. Studies in higher education, 40(6), 945-956. https://doi.org/10.1080/03075079.2013.842216

Biology teachers in a UK university expressed a majority view that student learning autonomy increases with progression through university. A minority suggested that pre-existing diversity in learning autonomy was more important and that individuals... Read More about Teacher and student perceptions of the development of learner autonomy : a case study in the biological sciences.

Greater than the sum of the parts? Unpacking ethics of care within a community supported agriculture scheme (2014)
Book Chapter
Cox, R., Kneafsey, M., Holloway, L., Dowler, E., & Venn, L. (2014). Greater than the sum of the parts? Unpacking ethics of care within a community supported agriculture scheme. In M. K. Goodman, & C. Sage (Eds.), Food Transgressions: Making Sense of Contemporary Food Politics (61-81). Ashgate. https://doi.org/10.4324/9781315582702

The concept of the moral economy directs attention to the moral and ethical frameworks through which everyday decisions are framed and enacted. This chapter shows that by exposing the very real differences in the priorities and actions of EarthShare... Read More about Greater than the sum of the parts? Unpacking ethics of care within a community supported agriculture scheme.

A new stellar chemo-kinematic relation reveals the merger history of the milky way disk (2014)
Journal Article
Minchev, I., Chiappini, C., Martig, M., Steinmetz, M., De Jong, R. S., Boeche, C., Scannapieco, C., Zwitter, T., Wyse, R. F. G., Binney, J. J., Bland-Hawthorn, J., Bienaymé, O., Famaey, B., Freeman, K. C., Gibson, B. K., Grebel, E. K., Gilmore, G., Helmi, A., Kordopatis, G., Lee, Y. S., …Williams, M. (2014). A new stellar chemo-kinematic relation reveals the merger history of the milky way disk. Astrophysical journal. Letters, 781(1), L20. https://doi.org/10.1088/2041-8205/781/1/l20

The velocity dispersions of stars near the Sun are known to increase with stellar age, but age can be difficult to determine, so a proxy like the abundance of α elements (e.g., Mg) with respect to iron, [α/Fe], is used. Here we report an unexpected b... Read More about A new stellar chemo-kinematic relation reveals the merger history of the milky way disk.

'Picturesque and dramatic' or 'dull recitals of threadbare fare': good practice in history teaching in elementary schools in England, 1872-1905 (2014)
Journal Article
Smith, J. T. (2014). 'Picturesque and dramatic' or 'dull recitals of threadbare fare': good practice in history teaching in elementary schools in England, 1872-1905. Journal of Educational Administration and History, 46(1), 93-107. https://doi.org/10.1080/00220620.2014.856873

This article draws on late nineteenth- and early twentieth-century teaching manuals, reports of Her Majesty's Inspectors, history textbooks ('readers'), other administrators' and teachers' accounts, policy documents and pupils' reminiscences to refut... Read More about 'Picturesque and dramatic' or 'dull recitals of threadbare fare': good practice in history teaching in elementary schools in England, 1872-1905.

Making meat collectivities : entanglements of geneticisation, integration and contestation in livestock breeding (2014)
Book Chapter
Gibbs, D., Holloway, L., Gilna, B., & Morris, C. (2014). Making meat collectivities : entanglements of geneticisation, integration and contestation in livestock breeding. In M. K. Goodman, & C. Sage (Eds.), Food Transgressions : Making Sense of Contemporary Food Politics (155-180). Routledge. https://doi.org/10.4324/9781315582702

To explore some of the contours of this meat ‘supply chain integration’ - ‘the phrase of the moment’ according to Farmers Weekly - this chapter draws on research conducted as part of a project exploring the effects of the emergence of particular type... Read More about Making meat collectivities : entanglements of geneticisation, integration and contestation in livestock breeding.

Efficient compact micro DBD plasma reactor for ozone generation for industrial application in liquid and gas phase systems (2014)
Journal Article
Kuvshinov, D., Lozano-Parada, J., Siswanto, A., & Zimmerman, W. (2014). Efficient compact micro DBD plasma reactor for ozone generation for industrial application in liquid and gas phase systems. International journal of chemical, molecular, nuclear, materials and metallurgical engineering, 8(1), 80-83. https://doi.org/10.5281/zenodo.1090542

Ozone is well known as a powerful, fast reacting oxidant. Ozone based processes produce no by-product residual as non-reacted ozone decomposes to molecular oxygen. Therefore an application of ozone is widely accepted as one of the main approaches for... Read More about Efficient compact micro DBD plasma reactor for ozone generation for industrial application in liquid and gas phase systems.

The Aden pivot? British counter-insurgency after Aden (2014)
Journal Article
Dingli, S., & Kennedy, C. (2014). The Aden pivot? British counter-insurgency after Aden. Civil Wars, 16(1), 86-104. https://doi.org/10.1080/13698249.2014.904987

This article argues that the Aden Insurgency was a pivotal moment in the history of British counter-insurgency. We argue that it was in Aden where the newfound strength of human rights discourse, embodied in Amnesty International, and of anti-colonia... Read More about The Aden pivot? British counter-insurgency after Aden.

Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans (2014)
Journal Article
Giuntini, F., Bryden, F., Daly, R., Scanlan, E. M., & Boyle, R. W. (2014). Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans. Organic & biomolecular chemistry, 12(8), 1203-1206. https://doi.org/10.1039/c3ob42306a

Fully deprotected alkynyl-functionalised mono- and oligosaccharides undergo CuAAC-based conjugation with water-soluble porphyrin azides in aqueous environments. The mild reaction conditions are fully compatible with the presence of labile glycosidic... Read More about Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans.

Users Guide to Ecohydraulic Modelling and Experimentation: Experience of the Ecohydraulic Research Team (PISCES) of the HYDRALAB Network (2014)
Book
Frostick, L., Thomas, R., Johnson, M., Rice, S., & McLelland, S. (Eds.). (2014). Users Guide to Ecohydraulic Modelling and Experimentation: Experience of the Ecohydraulic Research Team (PISCES) of the HYDRALAB Network. CRC Press. https://doi.org/10.1201/b16630

Users Guide to Ecohydraulic Modelling and Experimentation has been compiled by the interdisciplinary team of expert ecologists, geomorphologists, sedimentologists, hydraulicists and engineers involved in HYDRALAB IV, the European Integrated Infrastru... Read More about Users Guide to Ecohydraulic Modelling and Experimentation: Experience of the Ecohydraulic Research Team (PISCES) of the HYDRALAB Network.

Education associated with a delayed onset of terminal decline (2014)
Journal Article
Terrera, G. M., Minett, T., Brayne, C., & Matthews, F. E. (2014). Education associated with a delayed onset of terminal decline. Age and ageing, 43(1), 26-31. https://doi.org/10.1093/ageing/aft150

Background: the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. Objective: to investiga... Read More about Education associated with a delayed onset of terminal decline.

Brain haemosiderin in older people: Pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds (2014)
Journal Article
Janaway, B. M., Simpson, J. E., Hoggard, N., Highley, J. R., Forster, G., Drew, D., Gebril, O. H., Matthews, F. E., Brayne, C., Wharton, S. B., & Ince, P. G. (2014). Brain haemosiderin in older people: Pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds. Neuropathology and Applied Neurobiology, 40(3), 258-269. https://doi.org/10.1111/nan.12062

Introduction: Magnetic resonance imaging (MRI) cerebral microbleeds (CMB) arise from ferromagnetic haemosiderin iron assumed to derive from extravasation of erythrocytes. Light microscopy of ageing brain frequently reveals foci of haemosiderin from s... Read More about Brain haemosiderin in older people: Pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds.

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