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All Outputs (4)

Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients (2018)
Journal Article
Maltby, V. E., Lea, R. A., Graves, M. C., Sanders, K. A., Benton, M. C., Tajouri, L., …Lechner-Scott, J. (2018). Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients. Scientific reports, 8, Article 17418. https://doi.org/10.1038/s41598-018-35603-0

Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system. The inflammatory process in MS is driven by both T and B cells and current therapies are targeted to each of these cell types. Epigenetic mechanis... Read More about Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients.

Ultra-violet body painting: A new tool in the spectrum of anatomy education (2018)
Journal Article
Finn, G. M., Bazira, P. J., Bateman, J., & Sanders, K. A. (2018). Ultra-violet body painting: A new tool in the spectrum of anatomy education. European Journal of Anatomy, 22(6), 521-527

This descriptive article explores the use of ultraviolet (UV) body painting within anatomy education. Whilst the use of body painting is not new, UV paint has not previously been used within medical education. It is well documented that body painting... Read More about Ultra-violet body painting: A new tool in the spectrum of anatomy education.

DNA methylation changes in CD4+ T cells isolated from multiple sclerosis patients on dimethyl fumarate (2018)
Journal Article
Maltby, V. E., Lea, R. A., Ribbons, K. A., Sanders, K. A., Kennedy, D., Min, M., …Lechner-Scott, J. (2018). DNA methylation changes in CD4+ T cells isolated from multiple sclerosis patients on dimethyl fumarate. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 4(3), https://doi.org/10.1177/2055217318787826

Background: Dimethyl fumarate is an oral treatment for multiple sclerosis, whose mechanism of action is not fully understood. Objective: To investigate the effects of dimethyl fumarate on DNA methylation in the CD4+ T cells of multiple sclerosis pati... Read More about DNA methylation changes in CD4+ T cells isolated from multiple sclerosis patients on dimethyl fumarate.

Erythrocyte microRNA sequencing reveals differential expression in relapsing-remitting multiple sclerosis (2018)
Journal Article
Groen, K., Maltby, V. E., Lea, R. A., Sanders, K. A., Fink, J. L., Scott, R. J., …Lechner-Scott, J. (2018). Erythrocyte microRNA sequencing reveals differential expression in relapsing-remitting multiple sclerosis. Journal Title BMC Medical Genomics, 11(1), Article 48. https://doi.org/10.1186/s12920-018-0365-7

Background: There is a paucity of knowledge concerning erythrocytes in the aetiology of Multiple Sclerosis (MS) despite their potential to contribute to disease through impaired antioxidant capacity and altered haemorheological features. Several stud... Read More about Erythrocyte microRNA sequencing reveals differential expression in relapsing-remitting multiple sclerosis.