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Radical Cystectomy Against Intravesical BCG for High-Risk High-Grade Nonmuscle Invasive Bladder Cancer: Results From the Randomized Controlled BRAVO-Feasibility Study (2021)
Journal Article
Brown, J. M., Croft, J., Poad, H., Bell, R., Collinson, M., Gordon, K., Dooldeniya, M., Conroy, S., Catto, J. W., Noon, A. P., Simms, M., Chahal, R., Jain, S., Koenig, P., Johnson, M., Twiddy, M., & Goodwin, L. (2021). Radical Cystectomy Against Intravesical BCG for High-Risk High-Grade Nonmuscle Invasive Bladder Cancer: Results From the Randomized Controlled BRAVO-Feasibility Study. Journal of Clinical Oncology, 39(3), 202-214. https://doi.org/10.1200/JCO.20.01665

PURPOSE: High-grade nonmuscle invasive bladder cancer (HRNMIBC) is a heterogeneous disease. Treatments include intravesical maintenance Bacillus Calmette-Guerin (mBCG) and radical cystectomy (RC). We wanted to understand whether a randomized trial co... Read More about Radical Cystectomy Against Intravesical BCG for High-Risk High-Grade Nonmuscle Invasive Bladder Cancer: Results From the Randomized Controlled BRAVO-Feasibility Study.

Age dissection of the Milky Way discs: Red giants in the Kepler field (2021)
Journal Article
Miglio, A., Chiappini, C., Mackereth, J. T., Davies, G. R., Brogaard, K., Casagrande, L., …Mandel, I. (2021). Age dissection of the Milky Way discs: Red giants in the Kepler field. Astronomy and Astrophysics, 645, Article A85. https://doi.org/10.1051/0004-6361/202038307

Ensemble studies of red-giant stars with exquisite asteroseismic (Kepler), spectroscopic (APOGEE), and astrometric (Gaia) constraints offer a novel opportunity to recast and address long-standing questions concerning the evolution of stars and of the... Read More about Age dissection of the Milky Way discs: Red giants in the Kepler field.

Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (Protocol) (2021)
Journal Article
Crane, H., Boam, G., Carradice, D., Vanicek, N., Twiddy, M., & Smith, G. E. (2021). Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (Protocol). Cochrane Database of Systematic Reviews, 2021(1), Article CD013839. https://doi.org/10.1002/14651858.CD013839

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of through-knee amputation compared to above-knee amputation on clinical and rehabilitation outcomes and complication rates in... Read More about Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (Protocol).

Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles (2021)
Journal Article
Baghdadi, N. E., Burke, B. P., Alresheedi, T., Nigam, S., Saeed, A., Almutairi, F., Domarkas, J., Khan, A., & Archibald, S. J. (2021). Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles. Dalton Transactions : an international journal of inorganic chemistry, 50(5), 1599-1603. https://doi.org/10.1039/d0dt02626c

The CXCR4 chemokine receptor is an important biomolecular target in cancer diagnostics and therapeutics. In a new multivalent approach, iron oxide nanoparticles were conjugated with multiple binding units of a low affinity azamacrocylic CXCR4 antagon... Read More about Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles.

Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia (2021)
Journal Article
Dodds, R. M., Murray, J. C., Granic, A., Hurst, C., Uwimpuhwe, G., Richardson, S., Brayne, C., Matthews, F. E., Sayer, A. A., Arthur, A., Baldwin, C., Barnes, L. E., Comas-Herrera, A., Dening, T., Forster, G., Harrison, S., Ince, P. G., Jagger, C., McKeith, I. G., Parry, B., …Woods, B. (2021). Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia. Journal of Cachexia, Sarcopenia and Muscle, 12(2), 308-318. https://doi.org/10.1002/jcsm.12660

Background: Poor performance in the 5-chair stand test (5-CST) indicates reduced lower limb muscle strength. The 5-CST has been recommended for use in the initial assessment of sarcopenia, the accelerated loss of muscle strength and mass. In order to... Read More about Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia.

Artificial intelligence-driven music biometrics influencing customers’ retail buying behavior (2021)
Journal Article
Rodgers, W., Yeung, F., Odindo, C., & Degbey, W. Y. (2021). Artificial intelligence-driven music biometrics influencing customers’ retail buying behavior. Journal of business research, 126, 401-414. https://doi.org/10.1016/j.jbusres.2020.12.039

This study examines the digital transformation effects of artificial intelligence (AI)-based facial and music biometrics on customers' cognitive and emotional states and how these effects influence their behavioral responses on value creation. Using... Read More about Artificial intelligence-driven music biometrics influencing customers’ retail buying behavior.

Evaluating regional spatial imaginaries: the Oxford–Cambridge Arc (2021)
Journal Article
Valler, D., Jonas, A. E., & Robinson, L. (in press). Evaluating regional spatial imaginaries: the Oxford–Cambridge Arc. Territory, Politics, Governance, https://doi.org/10.1080/21622671.2020.1851751

© 2020 Regional Studies Association. The process of imagination is central to region formation, underpinning the spatial definition and territorial bounding of areas, the development of spatial identity and institutional capacity, and the cultivation... Read More about Evaluating regional spatial imaginaries: the Oxford–Cambridge Arc.

Studying animal innovation at the individual level: A ratings-based assessment in capuchin monkeys (Sapajus [Cebus] sp.). (2021)
Journal Article
Morton, F. B., Buchanan-Smith, H. M., Brosnan, S. F., Thierry, B., Paukner, A., Essler, J. L., Marcum, C. S., & Lee, P. C. (2021). Studying animal innovation at the individual level: A ratings-based assessment in capuchin monkeys (Sapajus [Cebus] sp.). Journal of Comparative Psychology, 135(2), 258-265. https://doi.org/10.1037/com0000264

Large-scale studies of individual differences in innovative behavior among nonhuman animals are rare because of logistical difficulties associated with obtaining observational data on a large number of innovative individuals across multiple locations... Read More about Studying animal innovation at the individual level: A ratings-based assessment in capuchin monkeys (Sapajus [Cebus] sp.)..

Personality structure in bottlenose dolphins (Tursiops truncatus). (2021)
Journal Article
Morton, F. B., Robinson, L. M., Brando, S., & Weiss, A. (2021). Personality structure in bottlenose dolphins (Tursiops truncatus). Journal of Comparative Psychology, 135(2), 219-231. https://doi.org/10.1037/com0000259

Comparative studies can help identify selective pressures that contributed to species differences in the number and composition of personality domains. Despite being adapted to an aquatic lifestyle and last sharing a common ancestor with primates som... Read More about Personality structure in bottlenose dolphins (Tursiops truncatus)..

Stock market volatility and jumps in times of uncertainty (2021)
Journal Article
Megaritis, A., Vlastakis, N., & Triantafyllou, A. (2021). Stock market volatility and jumps in times of uncertainty. Journal of International Money and Finance, 113, Article 102355. https://doi.org/10.1016/j.jimonfin.2021.102355

In this paper we examine the predictive power of latent macroeconomic uncertainty on US stock market volatility and jump tail risk. We find that increasing macroeconomic uncertainty predicts a subsequent rise in volatility and price jumps in the US e... Read More about Stock market volatility and jumps in times of uncertainty.

An Ambitious Primary School Curriculum (2021)
Book
Glazzard, J., & Stones, S. (2021). An Ambitious Primary School Curriculum. Critical Publishing

This book offers comprehensive guidance to support those involved in primary education in developing the curriculum to meet the requirements of the new Ofsted (2019) framework.

Radiological anatomy of the abdomen (2021)
Journal Article
Fang, C., Kane, P., Bazira, P. J., & Ben Cresswell, A. (2021). Radiological anatomy of the abdomen. Surgery (Oxford), 39(2), 61-74. https://doi.org/10.1016/j.mpsur.2020.12.001

Advances in technology have led to significant developments in techniques for imaging the abdominal and pelvic organs, in both the elective and emergency surgical settings. Improvements in the quality and availability of imaging has had a profound ef... Read More about Radiological anatomy of the abdomen.

Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia (2021)
Journal Article
Barlow, J., Sfyri, P. P., Mitchell, R., Verpoorten, S., Scully, D., Andreou, C., Papadopoulos, P., Patel, K., & Matsakas, A. (2021). Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia. Experimental Physiology, 106(3), 700-713. https://doi.org/10.1113/ep088937

Muscle satellite cells are important stem cells for skeletal muscle regeneration and repair after injury. ApoE‐deficient mice, an established mouse model of hyperlipidaemia and atherosclerosis, show evidence of oxidative stress‐induced lesions and fa... Read More about Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia.

Subcutaneous furosemide in advanced heart failure: service improvement project (2021)
Journal Article
Birch, F., Boam, E., Parsons, S., Ghosh, J., & Johnson, M. J. (in press). Subcutaneous furosemide in advanced heart failure: service improvement project. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2020-002803

Objectives: In severe heart disease, parenteral administration of loop diuretic is often needed. We present clinical outcomes from episodes of care using subcutaneous continuous infusion of furosemide (CSCI-furosemide).

Methods: Retrospective revi... Read More about Subcutaneous furosemide in advanced heart failure: service improvement project.

Improving the Reporting of Primary Care Research: An International Survey of Researchers (2021)
Journal Article
Phillips, W. R., Sturgiss, E., Hunik, L., Glasziou, P. P., olde Hartman, T., Orkin, A., Reeve, J., Russell, G. M., & van Weel, C. (2021). Improving the Reporting of Primary Care Research: An International Survey of Researchers. Journal of the American Board of Family Medicine, 34(1), 12-21. https://doi.org/10.3122/jabfm.2021.01.200266

PURPOSE: To assess opportunities to improve reporting of primary care (PC) research to better meet the needs of its varied users. METHODS: International, interprofessional online survey of PC researchers and users, 2018 to 2019. Respondents used Like... Read More about Improving the Reporting of Primary Care Research: An International Survey of Researchers.

Fetal alcohol spectrum disorders: An overview of current evidence and activities in the UK (2021)
Journal Article
Schölin, L., Mukherjee, R. A., Aiton, N., Blackburn, C., Brown, S., Flemming, K. M., …Cook, P. A. (2021). Fetal alcohol spectrum disorders: An overview of current evidence and activities in the UK. Archives of Disease in Childhood, 106(7), 636-640. https://doi.org/10.1136/archdischild-2020-320435

Estimates for the UK suggest that alcohol consumption during pregnancy and prevalence of fetal alcohol spectrum disorder (FASD) - the most common neurodevelopmental condition - are high. Considering the significant health and social impacts of FASD,... Read More about Fetal alcohol spectrum disorders: An overview of current evidence and activities in the UK.

Neurokinin-1 receptor (NK-1R) antagonists: potential targets in the treatment of glioblastoma multiforme (2021)
Journal Article
Afshari, A. R., Motamed-Sanaye, A., Sabri, H., Soltani, A., Karkon-Shayan, S., Radvar, S., Javid, H., Mollazadeh, H., Sathyapalan, T., & Sahebkar, A. (2021). Neurokinin-1 receptor (NK-1R) antagonists: potential targets in the treatment of glioblastoma multiforme. Current medicinal chemistry, 28(24), 4877-4892. https://doi.org/10.2174/0929867328666210113165805

The current standard of care in glioblastoma multiforme (GBM), as the most morbid brain tumor, is not adequate, despite substantial progress in cancer therapy. Among patients receiving current standard treatments, including surgery, irradiation, and... Read More about Neurokinin-1 receptor (NK-1R) antagonists: potential targets in the treatment of glioblastoma multiforme.

Bayesian Value-at-Risk backtesting: The case of annuity pricing (2021)
Journal Article
Leung, M., Li, Y., Pantelous, A. A., & Vigne, S. A. (in press). Bayesian Value-at-Risk backtesting: The case of annuity pricing. European journal of operational research, https://doi.org/10.1016/j.ejor.2020.12.051

We propose new Unconditional, Independence and Conditional Coverage VaR-forecast backtests for the case of annuity pricing under a Bayesian framework that significantly minimise the direct and indirect effects of p-hacking or other biased outcomes in... Read More about Bayesian Value-at-Risk backtesting: The case of annuity pricing.

The role of intermolecular interactions in stabilizing the structure of the nematic twist-bend phase (2021)
Journal Article
Merkel, K., Loska, B., Welch, C., Mehl, G. H., & Kocot, A. (2021). The role of intermolecular interactions in stabilizing the structure of the nematic twist-bend phase. RSC advances, 11(5), 2917-2925. https://doi.org/10.1039/d0ra10481g

The understanding of the relationship between molecular structure and the formation of the nematic twist-bend phase is still at an early stage of development. This is mainly related to molecular geometry, while the correlation between the nematic twi... Read More about The role of intermolecular interactions in stabilizing the structure of the nematic twist-bend phase.