Quantitative Proteomics Identifies Reduced NRF2 Activity and Mitochondrial Dysfunction in Atopic Dermatitis
(2022)
Journal Article
Koch, M., Kockmann, T., Rodriguez, E., Wehkamp, U., Hiebert, P., Ben-Yehuda Greenwald, M., Stölzl, D., Beer, H. D., Tschachler, E., Weidinger, S., Werner, S., & auf dem Keller, U. (2023). Quantitative Proteomics Identifies Reduced NRF2 Activity and Mitochondrial Dysfunction in Atopic Dermatitis. Journal of Investigative Dermatology, 143(2), 220-231.e7. https://doi.org/10.1016/j.jid.2022.08.048
Atopic dermatitis is the most common inflammatory skin disease and is characterized by a deficient epidermal barrier and cutaneous inflammation. Genetic studies suggest a key role of keratinocytes in atopic dermatitis pathogenesis, but the alteration... Read More about Quantitative Proteomics Identifies Reduced NRF2 Activity and Mitochondrial Dysfunction in Atopic Dermatitis.