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All Outputs (645)

How can we optimize antifungal use and stewardship in the treatment of acute leukemia? (2024)
Journal Article
Taynton, T., Allsup, D., & Barlow, G. (2024). How can we optimize antifungal use and stewardship in the treatment of acute leukemia?. Expert Review of Hematology, https://doi.org/10.1080/17474086.2024.2383401

Introduction: The global need for antifungal stewardship is driven by spreading antimicrobial and antifungal resistance. Triazoles are the only oral and relatively well-tolerated class of antifungal medications, and usage is associated with acquired... Read More about How can we optimize antifungal use and stewardship in the treatment of acute leukemia?.

The ten-year anniversary of public procurement reforms: a critical assessment of the European Union public procurement Directives (2024)
Journal Article
Bovis, C. H. (2024). The ten-year anniversary of public procurement reforms: a critical assessment of the European Union public procurement Directives. ERA-Forum, https://doi.org/10.1007/s12027-024-00798-5

This article evaluates the objectives of the legal framework on public procurement in the European Union and assesses its contribution to the internal market. The author provides for a critical analysis of the evolution of the public procurement acqu... Read More about The ten-year anniversary of public procurement reforms: a critical assessment of the European Union public procurement Directives.

Factors influencing European river lamprey passage at a tidal river barrier (2024)
Journal Article
Lothian, A. J., Bolland, J. D., Albright, A. J., Jubb, W. M., Bubb, D. H., Noble, R. A., Nunn, A. D., Dodd, J. R., Tummers, J. S., & Lucas, M. C. (2024). Factors influencing European river lamprey passage at a tidal river barrier. Hydrobiologia, https://doi.org/10.1007/s10750-024-05633-z

Understanding and improving passage by diadromous species at tidal barriers is less well advanced than that for non-tidal anthropogenic river barriers. This study assessed factors affecting upstream passage of anadromous river lamprey (Lampetra fluvi... Read More about Factors influencing European river lamprey passage at a tidal river barrier.

The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies (2024)
Journal Article
Sykes, D. L., Mason, P., Rahunathan, N., Hart, S. P., Morice, A. H., & Crooks, M. G. (2024). The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies. Lung, https://doi.org/10.1007/s00408-024-00729-8

Introduction: Azithromycin is an effective treatment for various respiratory conditions but its effect on cough is poorly understood. We synthesised data from randomised controlled trials (RCTs) and noncomparative studies (NCT) examining its effect o... Read More about The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies.

Selective detection of paraquat by a cucurbit[7]uril-based fluorescent probe (2024)
Journal Article
Shan, P. H., Pan, D. W., Li, C. R., Meng, T. H., Redshaw, C., Tao, Z., & Xiao, X. (2024). Selective detection of paraquat by a cucurbit[7]uril-based fluorescent probe. Journal of Pesticide Science, 49(2), 114-121. https://doi.org/10.1584/JPESTICS.D23-062

A simple fluorescent “on-off” system that can be utilized for the selective identification and determination of paraquat (PQ) is presented herein. 1H NMR spectroscopic data indicated that in aqueous solution the alkaloid palmatine can be partially en... Read More about Selective detection of paraquat by a cucurbit[7]uril-based fluorescent probe.

Damages in Public Procurement: Triple Damages Claims Available for Breaches of Public Procurement Law (2024)
Journal Article
Bovis, C. (2024). Damages in Public Procurement: Triple Damages Claims Available for Breaches of Public Procurement Law. European Procurement and Public Private Partnership Law Review, 19(2), 104-109. https://doi.org/10.21552/epppl/2024/2/5

The Remedies Directives leave Member States with a wide discretion as to the creation of the appropriate forum to receive complaints and legal actions against decisions of contracting authorities and utilities, as well as action for damages in public... Read More about Damages in Public Procurement: Triple Damages Claims Available for Breaches of Public Procurement Law.

Experimental development of lightweight manipulators with improved design cycle time that leverages off-the-shelf robotic arm components (2024)
Journal Article
Abbas, M. R., Ahsan, M., & Iqbal, J. (2024). Experimental development of lightweight manipulators with improved design cycle time that leverages off-the-shelf robotic arm components. PLoS ONE, 19(7), Article e0305379. https://doi.org/10.1371/journal.pone.0305379

The growing market for lightweight robots inspires new use-cases, such as collaborative manipulators for human-centered automation. However, widespread adoption faces obstacles due to high R&D costs and longer design cycles, although rapid advances i... Read More about Experimental development of lightweight manipulators with improved design cycle time that leverages off-the-shelf robotic arm components.

Redefining Digital Twins - A Wind Energy Operations and Maintenance Perspective (2024)
Presentation / Conference Contribution
Tuton, E., Ma, X., & Dethlefs, N. (2024, May). Redefining Digital Twins - A Wind Energy Operations and Maintenance Perspective. Presented at The Science of Making Torque from Wind (TORQUE 2024), Florence, Italy

Digital Twin (DT) technology has seen an explosion in popularity, with wind energy no exception. This is particularly true for Operations & Maintenance (O&M) applications. However, this expanded use has been accompanied by loose, conflicting, definit... Read More about Redefining Digital Twins - A Wind Energy Operations and Maintenance Perspective.

Phase-Based Adaptive Fractional LQR for Inverted-Pendulum-Type Robots: Formulation and Verification (2024)
Journal Article
Saleem, O., & Iqbal, J. (2024). Phase-Based Adaptive Fractional LQR for Inverted-Pendulum-Type Robots: Formulation and Verification. IEEE Access, 12, 93185-93196. https://doi.org/10.1109/ACCESS.2024.3415494

The underlying principles of inverted pendulums are widely applied to develop stabilization control strategies for under-actuated robotic systems in various applications. This article methodically designs an adaptive fractional-order linear quadratic... Read More about Phase-Based Adaptive Fractional LQR for Inverted-Pendulum-Type Robots: Formulation and Verification.

Operationalising the Recovery College model with people living with dementia: a realist review (2024)
Journal Article
Handley, M., Wheeler, C., Duddy, C., Wong, G., Birt, L., Fox, C., Moniz-Cook, E., Hackmann, C., Teague, B., & West, J. (2024). Operationalising the Recovery College model with people living with dementia: a realist review. Aging and Mental Health, 28(8), 1078-1089. https://doi.org/10.1080/13607863.2024.2356878

Objectives: Post-diagnostic support is a significant factor in facilitating personal recovery following a diagnosis of dementia, but access is often inconsistent and insufficient. Recovery Colleges offer peer-led, co-produced courses that can support... Read More about Operationalising the Recovery College model with people living with dementia: a realist review.

Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men (2024)
Journal Article
Friedrich, C., Singh, D., Francke, K., Klein, S., Hetzel, T., Zolk, O., Gashaw, I., Scheerans, C., & Morice, A. (2024). Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men. British Journal of Clinical Pharmacology, https://doi.org/10.1111/bcp.16091

Aims: We report on investigations exploring the P2X3-receptor antagonist filapixant's effect on taste perception and cough-reflex sensitivity and describe its pharmacokinetics, including its CYP3A4-interaction potential. Methods: In a randomized, pla... Read More about Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men.

Environmental behaviour of iron and steel slags in coastal settings (2024)
Journal Article
Riley, A. L., Cameron, J., Burke, I. T., Onnis, P., Macdonald, J. M., Gandy, C. J., Crane, R. A., Byrne, P., Comber, S., Jarvis, A. P., Hudson-Edwards, K. A., & Mayes, W. M. (2024). Environmental behaviour of iron and steel slags in coastal settings. Environmental science and pollution research, https://doi.org/10.1007/s11356-024-33897-4

Iron and steel slags have a long history of both disposal and beneficial use in the coastal zone. Despite the large volumes of slag deposited, comprehensive assessments of potential risks associated with metal(loid) leaching from iron and steel by-pr... Read More about Environmental behaviour of iron and steel slags in coastal settings.

Morphometric fingerprints and downslope evolution in bathymetric surveys: insights into morphodynamics of the Congo canyon-channel (2024)
Journal Article
Hasenhündl, M., Talling, P. J., Pope, E. L., Baker, M. L., Heijnen, M. S., Ruffell, S. C., da Silva Jacinto, R., Jacinto, S., Gaillot, A., Hage, S., Simmons, S. M., Heerema, C. J., McGhee, C., Clare, M. A., & Cartigny, M. J. (2024). Morphometric fingerprints and downslope evolution in bathymetric surveys: insights into morphodynamics of the Congo canyon-channel. Frontiers in Earth Science, 12, Article 1381019. https://doi.org/10.3389/feart.2024.1381019

Submarine canyons and channels are globally important pathways for sediment, organic carbon, nutrients and pollutants to the deep sea, and they form the largest sediment accumulations on Earth. However, studying these remote submarine systems compreh... Read More about Morphometric fingerprints and downslope evolution in bathymetric surveys: insights into morphodynamics of the Congo canyon-channel.

The symptom to assessment pathway for suspected chronic limb-threatening ischaemia (CLTI) affects quality of care: a process mapping exercise (2024)
Journal Article
Atkins, E., Kellar, I., Birmpili, P., Waton, S., Li, Q., Johal, A. S., …Cromwell, D. A. (2024). The symptom to assessment pathway for suspected chronic limb-threatening ischaemia (CLTI) affects quality of care: a process mapping exercise. BMJ Open Quality, 13(1), Article e002605. https://doi.org/10.1136/bmjoq-2023-002605

Background Delays in the pathway from first symptom to treatment of chronic limb-threatening ischaemia (CLTI) are associated with worse mortality and limb loss outcomes. This study examined the processes used by vascular services to provide urgent ca... Read More about The symptom to assessment pathway for suspected chronic limb-threatening ischaemia (CLTI) affects quality of care: a process mapping exercise.

Advancements in the management of obesity: a review of current evidence and emerging therapies (2024)
Journal Article
Abdalla Ahmed, M. A., Ssemmondo, E., Mark-Wagstaff, C., & Sathyapalan, T. (2024). Advancements in the management of obesity: a review of current evidence and emerging therapies. Expert Review of Endocrinology and Metabolism, 19(3), 257-268. https://doi.org/10.1080/17446651.2024.2347258

Introduction: Obesity is the modern world’s current epidemic, with substantial health and economic impact. This study aimed to provide a narrative overview of the past, currently available, and future treatment options that offer therapeutic and prev... Read More about Advancements in the management of obesity: a review of current evidence and emerging therapies.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. (2024). The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

Views of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: a qualitative study (2024)
Journal Article
Birtwistle, J., Allsop, M. J., Bradshaw, A., Millares Martin, P., Sleeman, K. E., Twiddy, M., & Evans, C. J. (2024). Views of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: a qualitative study. Palliative medicine, 38(7), 711-724. https://doi.org/10.1177/02692163241255511

Background: Digital approaches are being explored internationally to support the elicitation, documentation and sharing of advance care planning information. However, the views and experiences of patients and carers are little understood, impeding th... Read More about Views of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: a qualitative study.